CHEK2 and E2F1

  • Number of citations of the paper that reports this interaction (PMID 12717439)
  • 101
  • Data Source:
  • HPRD (in vivo, in vitro)

CHEK2

E2F1

Gene Name checkpoint kinase 2 E2F transcription factor 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 47 interactors: AATF APP ARHGAP1 ASF1A ATM ATR BRCA1 BRCA2 CDC25A CDC25C DAPK3 DBF4 E2F1 ELAVL1 ERCC6 FOXM1 KPNA2 LATS2 MDC1 MDM2 MDM4 MRC1 MSH2 MUS81 NBN NR4A1 PLK1 PLK3 POLR2L PPP2CA PPP2R2A PPP2R2B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RAD9A RCHY1 REV3L RNF8 SRPK1 STRAP TP53 TSSK1B VHL 70 interactors: ARID3A ATAD2 ATM ATR BRCA1 BRD2 BTRC CCNA1 CCNA2 CDK1 CDK2 CDK3 CDK7 CDKN2A CEBPE CHEK2 CREBBP CTDP1 CUL1 DDB2 E2F6 ERCC3 FHL2 GSK3B GTF2H1 HCFC1 IGF1 KAT5 KDM1A MDM2 MDM4 MGA MNAT1 MYBL2 NCOA3 NCOA6 NCOR2 NDN NDNL2 NFKB1 NPDC1 NRIP1 PARP1 PHB PKIB PRDM2 PURA RARA RB1 RNF144A SERTAD2 SETD7 SKP2 SP1 SP2 SP3 SP4 SPIB STAT1 STOML1 TBP TEAD3 TFDP1 TFDP2 TOPBP1 TP53 TP53BP1 TRRAP VHL YWHAQ
Entrez ID 11200 1869
HPRD ID 05084 01806
Ensembl ID ENSG00000183765 ENSG00000101412
Uniprot IDs O96017 Q01094 Q9BSD8
PDB IDs 1GXC 2CN5 2CN8 2W0J 2W7X 2WTC 2WTD 2WTI 2WTJ 2XBJ 2XK9 2XM8 2XM9 2YCF 2YCQ 2YCR 2YCS 2YIQ 2YIR 2YIT 3I6U 3I6W 3VA4 4A9R 4A9S 4A9T 4A9U 4BDA 4BDB 4BDC 4BDD 4BDE 4BDF 4BDG 4BDH 4BDI 4BDJ 4BDK 1H24 1O9K 2AZE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alleles  atm  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
box  coexpression  consensus  delays  displaying  dp  dps  e2fs  ectopic  emphasizes  exit  heterodimerization  heterodimers  lacks  members  namely  pocket  possesses  possessing  preference  quiescent  refer  shares  suppresses  transactivational  tttcccgc  tttcgcgc  unlike 
Tagcloud (Difference) ?
alleles  atm  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
box  coexpression  consensus  delays  displaying  dp  dps  e2fs  ectopic  emphasizes  exit  heterodimerization  heterodimers  lacks  members  namely  pocket  possesses  possessing  preference  quiescent  refer  shares  suppresses  transactivational  tttcccgc  tttcgcgc  unlike 
Tagcloud (Intersection) ?