CHEK2 and BRCA2

  • Number of citations of the paper that reports this interaction (PMID 14623252)
  • 0
  • Data Source:
  • BioGRID (unspecified method)

CHEK2

BRCA2

Gene Name checkpoint kinase 2 breast cancer 2, early onset
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 47 interactors: AATF APP ARHGAP1 ASF1A ATM ATR BRCA1 BRCA2 CDC25A CDC25C DAPK3 DBF4 E2F1 ELAVL1 ERCC6 FOXM1 KPNA2 LATS2 MDC1 MDM2 MDM4 MRC1 MSH2 MUS81 NBN NR4A1 PLK1 PLK3 POLR2L PPP2CA PPP2R2A PPP2R2B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RAD9A RCHY1 REV3L RNF8 SRPK1 STRAP TP53 TSSK1B VHL 34 interactors: ATM ATR BCCIP BRCA1 BUB1B C11orf30 CCNA2 CCNE1 CDK1 CDK2 CFAP52 CHEK2 DMC1 FANCD2 FANCE FANCG FLNA H2AFX HMG20B HNRNPC KAT2B MAGED1 NEDD4 PALB2 PLK1 RAD51 RPA1 SERPINH1 SHFM1 SMAD3 STAT5A TP53 UQCC1 USP11
Entrez ID 11200 675
HPRD ID 05084 02554
Ensembl ID ENSG00000183765 ENSG00000139618
Uniprot IDs O96017 P51587
PDB IDs 1GXC 2CN5 2CN8 2W0J 2W7X 2WTC 2WTD 2WTI 2WTJ 2XBJ 2XK9 2XM8 2XM9 2YCF 2YCQ 2YCR 2YCS 2YIQ 2YIR 2YIT 3I6U 3I6W 3VA4 4A9R 4A9S 4A9T 4A9U 4BDA 4BDB 4BDC 4BDD 4BDE 4BDF 4BDG 4BDH 4BDI 4BDJ 4BDK 1N0W 3EU7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alleles  atm  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
185delag  5677insa  adriamycin  brca1  breaks  camptothecin  cip1  clones  confer  doubling  du  germ  insbrca1  mdm  obvious  parental  probands  prostate  slightly  stably  strand  susceptibility  taxol  transfected  transgenes  vector  virtue  waf1  wtbrca1 
Tagcloud (Difference) ?
alleles  atm  brip1  cdh1  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
185delag  5677insa  adriamycin  breaks  camptothecin  cip1  clones  doubling  du  germ  insbrca1  mdm  obvious  parental  probands  prostate  slightly  stably  strand  susceptibility  taxol  transfected  transgenes  vector  virtue  waf1  wtbrca1 
Tagcloud (Intersection) ?
brca1  brca2  confer