CHEK2 and CDC25C

  • Number of citations of the paper that reports this interaction (PMID 9278512)
  • 268
  • Data Source:
  • HPRD (in vitro)

CHEK2

CDC25C

Gene Name checkpoint kinase 2 cell division cycle 25C
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 47 interactors: AATF APP ARHGAP1 ASF1A ATM ATR BRCA1 BRCA2 CDC25A CDC25C DAPK3 DBF4 E2F1 ELAVL1 ERCC6 FOXM1 KPNA2 LATS2 MDC1 MDM2 MDM4 MRC1 MSH2 MUS81 NBN NR4A1 PLK1 PLK3 POLR2L PPP2CA PPP2R2A PPP2R2B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RAD9A RCHY1 REV3L RNF8 SRPK1 STRAP TP53 TSSK1B VHL 29 interactors: BRSK1 BRSK2 CCNA2 CCNB1 CDK1 CDK2 CDS1 CHEK1 CHEK2 HRAS LCK LZTS1 MAPK1 MAPK14 MAPK3 MAPK9 MARK3 NEDD4 PCNA PIN1 PKN1 PLK1 PLK3 SRC TP53 YWHAB YWHAH YWHAQ YWHAZ
Entrez ID 11200 995
HPRD ID 05084 01146
Ensembl ID ENSG00000183765 ENSG00000158402
Uniprot IDs O96017 P30307
PDB IDs 1GXC 2CN5 2CN8 2W0J 2W7X 2WTC 2WTD 2WTI 2WTJ 2XBJ 2XK9 2XM8 2XM9 2YCF 2YCQ 2YCR 2YCS 2YIQ 2YIR 2YIT 3I6U 3I6W 3VA4 4A9R 4A9S 4A9T 4A9U 4BDA 4BDB 4BDC 4BDD 4BDE 4BDF 4BDG 4BDH 4BDI 4BDJ 4BDK 3BZI 3OP3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alleles  atm  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
acetyltransferase  acetyltransferases  aiding  ancient  assembled  box  caf  ccaat  collagen  disrupted  facilitating  gcn5  heterodimers  histocompatibility  lipase  nf  pivotal  possess  r2  reductase  ribonucleotide  transactivation  transfections  ubiquitous  y  ya  yb  yc 
Tagcloud (Difference) ?
alleles  atm  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
acetyltransferase  acetyltransferases  aiding  ancient  assembled  box  caf  ccaat  collagen  disrupted  facilitating  gcn5  heterodimers  histocompatibility  lipase  nf  pivotal  possess  r2  reductase  ribonucleotide  transactivation  transfections  ubiquitous  y  ya  yb  yc 
Tagcloud (Intersection) ?