CHEK2 and PPP2R2B

  • Number of citations of the paper that reports this interaction (PMID 16596250)
  • 9
  • Data Source:
  • HPRD (in vitro, in vivo)

CHEK2

PPP2R2B

Gene Name checkpoint kinase 2 protein phosphatase 2, regulatory subunit B, beta
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol dependence ( 19581569)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
Protein-Protein Interactions 47 interactors: AATF APP ARHGAP1 ASF1A ATM ATR BRCA1 BRCA2 CDC25A CDC25C DAPK3 DBF4 E2F1 ELAVL1 ERCC6 FOXM1 KPNA2 LATS2 MDC1 MDM2 MDM4 MRC1 MSH2 MUS81 NBN NR4A1 PLK1 PLK3 POLR2L PPP2CA PPP2R2A PPP2R2B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RAD9A RCHY1 REV3L RNF8 SRPK1 STRAP TP53 TSSK1B VHL 5 interactors: CHEK2 KLHL15 RAC1 TOP1 TP53
Entrez ID 11200 5521
HPRD ID 05084 05059
Ensembl ID ENSG00000183765 ENSG00000156475
Uniprot IDs O96017 Q00005
PDB IDs 1GXC 2CN5 2CN8 2W0J 2W7X 2WTC 2WTD 2WTI 2WTJ 2XBJ 2XK9 2XM8 2XM9 2YCF 2YCQ 2YCR 2YCS 2YIQ 2YIR 2YIT 3I6U 3I6W 3VA4 4A9R 4A9S 4A9T 4A9U 4BDA 4BDB 4BDC 4BDD 4BDE 4BDF 4BDG 4BDH 4BDI 4BDJ 4BDK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alleles  atm  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
allele  arg72pro  associates  curves  died  ethnically  gender  genotyped  genotypes  interested  kaplan  lifespan  lived  llis  log  longevity  mdm4  meier  rank  respective  rs1042522  rs1563828  rs2279744  rs319217  rs4245739  snp309  snp31826  snp34091  snps 
Tagcloud (Difference) ?
alleles  atm  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
allele  arg72pro  associates  curves  died  ethnically  gender  genotyped  genotypes  interested  kaplan  lifespan  lived  llis  log  longevity  mdm4  meier  rank  respective  rs1042522  rs1563828  rs2279744  rs319217  rs4245739  snp309  snp31826  snp34091  snps 
Tagcloud (Intersection) ?