SF3B3 and KIF13B

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		SF3B3	KIF13B
Description		splicing factor 3b subunit 3	kinesin family member 13B
Image
GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Cytoplasm Cytoskeleton Kinesin Complex Microtubule Axon Cell Projection
	Molecular Function	Nucleic Acid Binding Protein Binding U2 SnRNA Binding Protein-containing Complex Binding	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity Protein Kinase Binding 14-3-3 Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Regulation Of DNA Repair MRNA Processing RNA Splicing Negative Regulation Of Protein Catabolic Process Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription U2-type Prespliceosome Assembly	Protein Targeting Microtubule-based Movement Signal Transduction T Cell Activation Establishment Of Protein Localization Regulation Of Axonogenesis
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs		Quercetin
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061)	Apolipoprotein B levels ( 32203549) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Metabolite levels (X-11787) ( 23934736) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) PR interval in Tripanosoma cruzi seropositivity ( 24324551) Prostate cancer ( 33293427) Response to statin therapy ( 20339536)
Interacting Genes		108 interacting genes: APBB1 EFTUD2 EIF4ENIF1 EPS8 ERCC6 ERG HCK HGS HSPB1 KIF13B KLF10 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MPP3 NAGK NOL12 OSGEP PPIL1 PRKN PRPF40A RAD9A RBFOX2 RBM6 RNF10 RUFY2 SF3B1 SMAD5 SNRNP200 SREK1 TAF9 TCERG1 TOE1 U2AF2 USP7 WBP4 WWOX YWHAG ZNF579	4 interacting genes: DLG1 DLG4 MARK2 SF3B3
Entrez ID		23450	23303
HPRD ID		12027	09556
Ensembl ID		ENSG00000189091	ENSG00000197892
Uniprot IDs		A8K6V3 Q15393	Q9NQT8
PDB IDs		5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6AHD 6EN4 6FF4 6FF7 6QX9 6Y50 6Y5Q 7ABG 7ABH 7ABI 7B0I 7B91 7B92 7B9C 7DVQ 7EVN 7EVO 7KTS 7OMF 7ONB 7OPI 7Q3L 7Q4O 7Q4P 7QTT 7VPX 8CH6 8H6E 8H6J 8H6K 8H6L 8H7G 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y7E	2COW 3FM8 3GBJ 3MDB
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Metabolic Process Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Positive Regulation Of MRNA Catabolic Process RNA Destabilization Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Angiogenesis Positive Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cytokine Production Regulation Of Translation Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of MRNA Stability Negative Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Regulation Of RNA Stability Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Signal Transduction Negative Regulation Of Developmental Process Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Multicellular Organismal Process Regulation Of Endothelial Cell Migration Regulation Of MRNA Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway	Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Cell Polarity Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Cell Morphogenesis Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Ionotropic Glutamate Receptor Binding Receptor Localization To Synapse Receptor Clustering Protein Localization To Synapse Synaptic Membrane Lateral Plasma Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Protein-containing Complex Localization Neuromuscular Junction Protein Localization To Cell Junction Kinase Binding Postsynaptic Density Membrane P2Y1 Nucleotide Receptor Binding Regulation Of Cell Shape Regulation Of Anatomical Structure Morphogenesis Structural Constituent Of Postsynaptic Density Adherens Junction L27 Domain Binding Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Cell Junction Positive Regulation Of Cellular Component Organization MPP7-DLG1-LIN7 Complex Protein Localization To Cell Periphery Maintenance Of Postsynaptic Density Structure Lateral Loop Myelin Sheath Abaxonal Region AMPA Glutamate Receptor Clustering Neuroligin Family Protein Binding Microtubule Bundle Establishment Or Maintenance Of Cell Polarity Regulating Cell Shape Postsynaptic Density Regulation Of Potassium Ion Import NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Neurofibrillary Tangle Assembly U2 SnRNA Binding Protein-containing Complex Assembly D1 Dopamine Receptor Binding Negative Regulation Of P38MAPK Cascade Cortical Microtubule Organization Protein-containing Complex Organization Chemical Synaptic Transmission Hard Palate Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?