SF3B3 and TOE1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		SF3B3	TOE1
Gene Name		splicing factor 3b, subunit 3, 130kDa	target of EGR1, member 1 (nuclear)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nucleolus Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	Nucleic Acid Binding Protein Binding Metal Ion Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing Protein Complex Assembly RNA Splicing Gene Expression
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579	25 interactors: ABCF3 AGGF1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83
Entrez ID		23450	114034
HPRD ID		12027	18212
Ensembl ID			ENSG00000132773
Uniprot IDs		A8K6V3 Q15393	B4DEM6 Q96GM8
PDB IDs			2FC6
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Shape Regulation Of Cell Death Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Process Response To Transforming Growth Factor Beta Positive Regulation Of Apoptotic Signaling Pathway Respiratory Burst After Phagocytosis Negative Regulation Of Thymidylate Synthase Biosynthetic Process Negative Regulation Of Potassium Ion Export Cardiac Muscle Contraction Regulation Of Transcription From RNA Polymerase II Promoter Metabolic Process Heart Contraction Positive Regulation Of Response To DNA Damage Stimulus Peptidyl-amino Acid Modification Threonylcarbamoyladenosine Biosynthetic Process Leukocyte Migration Involved In Immune Response Regulation Of Heart Rate By Hormone N-acetylmannosamine Metabolic Process Response To Organic Substance Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Ossification Response To Growth Factor Positive Regulation Of Cell Death Actin Polymerization-dependent Cell Motility Striated Muscle Contraction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Peptide Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway N-acetylneuraminate Catabolic Process	MRNA Metabolic Process RNA Processing MRNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA 3'-end Processing RNA 3'-end Processing RNA Metabolic Process Termination Of RNA Polymerase II Transcription Gene Expression Nucleobase-containing Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Nuclear Export MRNA Transport Nitrogen Compound Metabolic Process RNA Transport Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Localization Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process Cytoplasmic Transport Establishment Of Localization In Cell Intracellular Transport RNA Catabolic Process Positive Regulation Of Synaptic Vesicle Priming Positive Regulation Of Synaptic Vesicle Exocytosis Interleukin-7-mediated Signaling Pathway Regulation Of MRNA Splicing, Via Spliceosome Nucleocytoplasmic Transport Cellular Metabolic Process Nuclear Transport Negative Regulation Of Hyaluronan Biosynthetic Process Cellular Response To Norepinephrine Stimulus Regulation Of Epithelial Cell Proliferation Regulation Of MRNA Processing PML Body Organization Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Negative Regulation Of T Cell Mediated Cytotoxicity Cellular Process
Tagcloud ?		advance albeit ascertain atlas cohorts document doi dx endocrine fulvestrant lcc2 lcc9 mcf modern modpathol november oncotype online paraffin parts publication publicly qrt sets sf3b1 splicing tamoxifen
Tagcloud (Difference) ?		advance albeit ascertain atlas cohorts document doi dx endocrine fulvestrant lcc2 lcc9 mcf modern modpathol november oncotype online paraffin parts publication publicly qrt sets sf3b1 splicing tamoxifen
Tagcloud (Intersection) ?