TOPBP1 and ATM

  • Number of citations of the paper that reports this interaction (PMID 11756551)
  • 48
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, in vivo)

TOPBP1

ATM

Gene Name topoisomerase (DNA) II binding protein 1 ATM serine/threonine kinase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 19 interactors: ABL1 AKT1 ATM BLM BMPR2 BRIP1 CHEK1 CLSTN1 E2F1 PML POLE PPP1CC RAD9A TBC1D4 TCFL5 TICRR TOP2B UBR5 ZBTB17 76 interactors: AATF ABL1 AP1B1 AP2A2 AP2B1 AP3B2 ATR BCL10 BLM BRCA1 BRCA2 CDC6 CDKN2C CHD4 CHEK1 CHEK2 CREB1 CSNK1D CXXC5 DAXX DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 EXO1 FANCD2 FOXO3 H2AFX HIF1A KAT5 KAT8 LIG4 MCM2 MDC1 MDM2 MDM4 MRE11A NBN PARP1 PEX5 POLR2A PRKDC PTS RAD17 RAD51 RAD9A RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SOCS1 SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 VPRBP WRN XPA XRCC5 ZEB1
Entrez ID 11073 472
HPRD ID 09678 06347
Ensembl ID ENSG00000163781 ENSG00000149311
Uniprot IDs A0AV47 A7E2X7 Q05BV8 Q92547 Q13315
PDB IDs 1WF6 2XNH 2XNK 3AL2 3AL3 3JVE 3OLC 3PD7 3UEN 3UEO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abrogates  atr  bona  checkpoint  chk1  clamp  claspin  damaging  extensively  fide  heterotetrameric  hus1  impacting  irradiation  lac  laco  lacr  lastly  localizes  onto  orphan  portion  rad1  rad9  repeats  repressor  rhino  tethering  uv 
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
Tagcloud (Difference) ?
abrogates  atr  bona  checkpoint  chk1  clamp  claspin  damaging  extensively  fide  heterotetrameric  hus1  impacting  irradiation  lac  laco  lacr  lastly  localizes  onto  orphan  portion  rad1  rad9  repeats  repressor  rhino  tethering  uv 
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
Tagcloud (Intersection) ?