CCDC106 and EIF1AD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC106	EIF1AD
Description		coiled-coil domain containing 106	eukaryotic translation initiation factor 1A domain containing
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding
	Biological Process		Translational Initiation
Pathways
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Serum uric acid levels ( 32271837)
Interacting Genes		26 interacting genes: APP ATF4 CACNA1S CEP19 COPS6 CRMP1 EEF1G EIF1AD ERG28 FAM9B KAT5 KBTBD7 L3MBTL2 LRIF1 MAGEA11 MAGOHB NAA10 NKAPD1 NUTF2 PRPF31 RBM48 RCOR3 SDCBP SETDB1 TP53 UTP14A	34 interacting genes: AP2M1 BEND7 CCDC106 CEP55 CEP76 DPPA2 DRC4 GCSAML GLYR1 GTF2H4 LNX1 MEOX2 MID2 MREG PAX6 PBX4 PICK1 PINX1 RASSF10 RBAK RBM48 SDCBP SDCBP2 STAT1 STX11 TBC1D5 TEPSIN TLE5 TNNI1 ZBTB14 ZBTB8A ZNF280A ZNF521 ZNF558
Entrez ID		29903	84285
HPRD ID		09995	14411
Ensembl ID		ENSG00000173581	ENSG00000175376
Uniprot IDs		K7EMI9 Q9BWC9	Q8N9N8
PDB IDs			2DGY 6ZXF 6ZXG 6ZXH
Enriched GO Terms of Interacting Partners?		Nucleoplasm Promoter-specific Chromatin Binding Molecular Function Activator Activity Nucleus Cellular Response To Glucose Starvation Cellular Response To Manganese Ion Negative Regulation Of Gene Expression Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Macromolecule Biosynthetic Process Response To Manganese Ion General Transcription Initiation Factor Binding Negative Regulation Of Biosynthetic Process Cytosol Acetyltransferase Activity Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Transcription Regulator Complex	Regulation Of Receptor Internalization Positive Regulation Of Receptor Internalization Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor-mediated Endocytosis AP-2 Adaptor Complex Protein Binding
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