CCDC106 and NAA10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC106	NAA10
Description		coiled-coil domain containing 106	N-alpha-acetyltransferase 10, NatA catalytic subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nucleolus Cytoplasm Cytosol Membrane NatA Complex
	Molecular Function	Protein Binding	Protein-N-terminal Amino-acid Acetyltransferase Activity Protein Binding N-acetyltransferase Activity Protein-N-terminal-alanine Acetyltransferase Activity Acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Ribosome Binding Protein N-terminal-serine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity
	Biological Process		Protein Acetylation N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation Chromosome Organization Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric
Pathways
Drugs
Diseases
GWAS			Systemic lupus erythematosus ( 26502338)
Interacting Genes		26 interacting genes: APP ATF4 CACNA1S CEP19 COPS6 CRMP1 EEF1G EIF1AD ERG28 FAM9B KAT5 KBTBD7 L3MBTL2 LRIF1 MAGEA11 MAGOHB NAA10 NKAPD1 NUTF2 PRPF31 RBM48 RCOR3 SDCBP SETDB1 TP53 UTP14A	59 interacting genes: ACOT12 BAALC BCOR CALCOCO2 CASP8AP2 CCDC106 CCDC174 CDC25A CEBPA CEP44 CFTR CREB3 CREBRF CTNNB1 DDIT4L DHX57 EHMT2 FIP1L1 GPATCH2L H4C1 HIF1A HIF1AN HSPA4 HYPK KIFAP3 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 MCRS1 MDM4 MEOX2 MKRN1 MRPS11 NAA15 NAA16 NAA50 NAT1 NAT2 NOXA1 PDE4DIP PGK1 PLSCR3 PPP2R3B PSME2 RAB3IP RBCK1 RCN3 RIMBP2 RPL26 SEMA3B SNX33 SSX2IP TAF7L TSEN54 UBC ZBTB14 ZNF202 ZNF655
Entrez ID		29903	8260
HPRD ID		09995	02056
Ensembl ID		ENSG00000173581	ENSG00000102030
Uniprot IDs		K7EMI9 Q9BWC9	B7Z9N2 P41227
PDB IDs			6C95 6C9M 6PPL 6PW9 9F1B 9F1C 9F1D 9FPZ 9FQ0
Enriched GO Terms of Interacting Partners?		Nucleoplasm Promoter-specific Chromatin Binding Molecular Function Activator Activity Nucleus Cellular Response To Glucose Starvation Cellular Response To Manganese Ion Negative Regulation Of Gene Expression Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Macromolecule Biosynthetic Process Response To Manganese Ion General Transcription Initiation Factor Binding Negative Regulation Of Biosynthetic Process Cytosol Acetyltransferase Activity Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Transcription Regulator Complex	Acetyltransferase Activity NatA Complex Cytosol N-terminal Protein Amino Acid Acetylation Protein Binding Arylamine N-acetyltransferase Activity Nucleus Protein Acetylation
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