GADD45G and LRIF1

Number of citations of the paper that reports this interaction (PubMedID 15383276)
0

Data Source:
HPRD (two hybrid)

		GADD45G	LRIF1
Description		growth arrest and DNA damage inducible gamma	ligand dependent nuclear receptor interacting factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromosome, Telomeric Region Barr Body Nucleus Nucleoplasm Chromosome Nuclear Matrix Centriolar Satellite
	Molecular Function	Protein Binding	Protein Binding Nuclear Retinoic Acid Receptor Binding
	Biological Process	Apoptotic Process Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of P38MAPK Cascade	Regulation Of DNA-templated Transcription Dosage Compensation By Inactivation Of X Chromosome
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Apolipoprotein A1 levels ( 32203549) Automobile speeding propensity ( 30643258) Brain morphology (MOSTest) ( 32665545) Fibrinogen levels ( 26561523 28107422) General cognitive ability ( 29844566) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Metabolic syndrome ( 31589552) Nonsyndromic cleft lip with cleft palate ( 28232668) Protein quantitative trait loci ( 18464913) Thyroglobulin plasma levels ( 30929638) Triglyceride levels ( 32154731 32203549)	Bone mineral content ( 31790847) Intraocular pressure ( 30591961)
Interacting Genes		74 interacting genes: ACTN1 AFAP1L1 APP ARPC5L BEND7 BLOC1S2 CCNB1 CDK1 CDK11A CDKN1A CEP57L1 CFAP44 CNOT9 CRIP2 DCTN2 DDAH2 DDIT4L EEF1A1 EEF1G EIF3G ENKD1 ESR1 EZH2 FAM156A FAM156B GADD45B GADD45GIP1 GDF9 GRAMD4 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN NMB PCNA PDE4DIP PDIA4 PHAX PIAS4 PLAGL2 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RASSF10 RBM48 RCN1 RDH13 REL RRP7A RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579 ZNF664 ZNF763	143 interacting genes: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BANP BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRACR2A CRADD CRCP CRCT1 CRIPTO DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FHL2 FOSL2 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 H3-4 HAP1 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NOC2L NR3C1 NRBP1 NTAQ1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR1C POLR2C POLR3F PPARG PQBP1 PRKAB2 PRKAR2A PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SNU13 SPATA18 SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSEN15 TSPAN6 UBE2V2 UNC119 VIM VPS26C WDR62 WWC1 ZNF24 ZNF410
Entrez ID		10912	55791
HPRD ID		05383	17975
Ensembl ID		ENSG00000130222	ENSG00000121931
Uniprot IDs		O95257	Q5T3J3
PDB IDs		2WAL 3FFM
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MiRNA Transcription Nuclear Receptor Activity Regulation Of MiRNA Transcription Protein Binding Regulation Of MiRNA Metabolic Process Nuclear Steroid Receptor Activity Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Cholesterol Storage Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin B1-CDK1 Complex PCNA-p21 Complex Peroxisome Proliferator Activated Receptor Signaling Pathway Microtubule Cytoskeleton Organization Involved In Mitosis RNA Polymerase II Transcription Regulator Complex Negative Regulation Of Gene Expression Sequence-specific DNA Binding Cyclin-dependent Protein Kinase Holoenzyme Complex Hormone-mediated Signaling Pathway Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Programmed Cell Death Intracellular Receptor Signaling Pathway Regulation Of RNA Metabolic Process Transcription Coactivator Binding Regulation Of Cell Population Proliferation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen-containing Compound Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport DNA Binding Domain Binding Negative Regulation Of Lipid Storage Regulation Of Apoptotic Process Regulation Of Attachment Of Spindle Microtubules To Kinetochore Centrosome Rhythmic Process Response To Estradiol Retinoic Acid Receptor Signaling Pathway Regulation Of Circadian Rhythm Microtubule Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Molecular Function Activator Activity Positive Regulation Of Lipoprotein Transport Establishment Of Organelle Localization Organelle Localization Chromatin Negative Regulation Of Metabolic Process Positive Regulation Of DNA Metabolic Process Chromatin Binding Positive Regulation Of RNA Metabolic Process Regeneration Positive Regulation Of Chromosome Segregation	Nucleus Nucleoplasm Protein Binding Cytoplasm Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Apoptotic Process Chromatin Binding Positive Regulation Of Programmed Cell Death Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Nuclear Receptor Activity Regulation Of Intracellular Signal Transduction Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Population Proliferation Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Cytosol Positive Regulation Of Apoptotic Process Nucleolus Negative Regulation Of Transcription By RNA Polymerase II Biological_process Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Development Negative Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Hemopoiesis Chromatin Organization Regulation Of Cell Differentiation Mononuclear Cell Differentiation Regulation Of Lymphocyte Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Signal Transduction Positive Regulation Of Fibroblast Proliferation DNA-directed RNA Polymerase Activity Positive Regulation Of Biosynthetic Process Chromatin Remodeling Regulation Of Cell Cycle Process Regulation Of DNA Repair Regulation Of Cell Cycle G1/S Phase Transition
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