GADD45G and FAM156B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GADD45G	FAM156B
Description		growth arrest and DNA damage inducible gamma	family with sequence similarity 156 member B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nuclear Envelope Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of P38MAPK Cascade
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Apolipoprotein A1 levels ( 32203549) Automobile speeding propensity ( 30643258) Brain morphology (MOSTest) ( 32665545) Fibrinogen levels ( 26561523 28107422) General cognitive ability ( 29844566) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Metabolic syndrome ( 31589552) Nonsyndromic cleft lip with cleft palate ( 28232668) Protein quantitative trait loci ( 18464913) Thyroglobulin plasma levels ( 30929638) Triglyceride levels ( 32154731 32203549)
Interacting Genes		74 interacting genes: ACTN1 AFAP1L1 APP ARPC5L BEND7 BLOC1S2 CCNB1 CDK1 CDK11A CDKN1A CEP57L1 CFAP44 CNOT9 CRIP2 DCTN2 DDAH2 DDIT4L EEF1A1 EEF1G EIF3G ENKD1 ESR1 EZH2 FAM156A FAM156B GADD45B GADD45GIP1 GDF9 GRAMD4 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN NMB PCNA PDE4DIP PDIA4 PHAX PIAS4 PLAGL2 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RASSF10 RBM48 RCN1 RDH13 REL RRP7A RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579 ZNF664 ZNF763	2 interacting genes: CRACR2A GADD45G
Entrez ID		10912	727866
HPRD ID		05383
Ensembl ID		ENSG00000130222	ENSG00000179304
Uniprot IDs		O95257	Q8NDB6
PDB IDs		2WAL 3FFM
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MiRNA Transcription Nuclear Receptor Activity Regulation Of MiRNA Transcription Protein Binding Regulation Of MiRNA Metabolic Process Nuclear Steroid Receptor Activity Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Cholesterol Storage Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin B1-CDK1 Complex PCNA-p21 Complex Peroxisome Proliferator Activated Receptor Signaling Pathway Microtubule Cytoskeleton Organization Involved In Mitosis RNA Polymerase II Transcription Regulator Complex Negative Regulation Of Gene Expression Sequence-specific DNA Binding Cyclin-dependent Protein Kinase Holoenzyme Complex Hormone-mediated Signaling Pathway Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Programmed Cell Death Intracellular Receptor Signaling Pathway Regulation Of RNA Metabolic Process Transcription Coactivator Binding Regulation Of Cell Population Proliferation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen-containing Compound Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport DNA Binding Domain Binding Negative Regulation Of Lipid Storage Regulation Of Apoptotic Process Regulation Of Attachment Of Spindle Microtubules To Kinetochore Centrosome Rhythmic Process Response To Estradiol Retinoic Acid Receptor Signaling Pathway Regulation Of Circadian Rhythm Microtubule Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Molecular Function Activator Activity Positive Regulation Of Lipoprotein Transport Establishment Of Organelle Localization Organelle Localization Chromatin Negative Regulation Of Metabolic Process Positive Regulation Of DNA Metabolic Process Chromatin Binding Positive Regulation Of RNA Metabolic Process Regeneration Positive Regulation Of Chromosome Segregation	Positive Regulation Of JNK Cascade Regulation Of JNK Cascade Positive Regulation Of MAPK Cascade Activation Of Store-operated Calcium Channel Activity Positive Regulation Of Store-operated Calcium Channel Activity Weibel-Palade Body Store-operated Calcium Entry Response To Histamine Regulation Of MAPK Cascade Specific Granule T-helper 1 Cell Differentiation Positive Regulation Of Cation Channel Activity Positive Regulation Of P38MAPK Cascade Positive Regulation Of Intracellular Signal Transduction Regulation Of P38MAPK Cascade T Cell Differentiation Involved In Immune Response Positive Regulation Of Ion Transmembrane Transporter Activity T-helper Cell Differentiation Immunological Synapse Positive Regulation Of Transporter Activity CD4-positive, Alpha-beta T Cell Differentiation Specific Granule Lumen CD4-positive, Alpha-beta T Cell Activation Positive Regulation Of Signal Transduction T Cell Activation Involved In Immune Response Alpha-beta T Cell Differentiation G Protein Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Cold-induced Thermogenesis Microtubule Organizing Center Regulation Of Transmembrane Transporter Activity Alpha-beta T Cell Activation Positive Regulation Of Calcium Ion Transport Regulation Of Monoatomic Ion Transmembrane Transporter Activity Trans-Golgi Network Membrane Regulation Of Intracellular Signal Transduction Positive Regulation Of Cation Transmembrane Transport Lymphocyte Activation Involved In Immune Response Positive Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Cold-induced Thermogenesis Leukocyte Activation Involved In Immune Response T Cell Differentiation Cell Activation Involved In Immune Response Cell Differentiation
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