LRIF1 and ATF3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LRIF1	ATF3
Gene Name		ligand dependent nuclear receptor interacting factor 1	activating transcription factor 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Microtubule Organizing Center Actin Cytoskeleton Nuclear Matrix	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Protein Binding Retinoic Acid Receptor Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Identical Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Gluconeogenesis Transcription, DNA-templated Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Cell Proliferation Endoplasmic Reticulum Unfolded Protein Response Skeletal Muscle Cell Differentiation Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			ATF4 activates genes PERK regulates gene expression Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		129 interactors: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRADD CRCT1 DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 HAP1 HIST3H3 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NHP2L1 NOC2L NR3C1 NRBP1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR2C POLR3F PPARG PQBP1 PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TDGF1 TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSPAN6 UBE2V2 VIM WDR62 WWC1 ZNF24	41 interactors: ATF2 ATF4 BATF BATF3 CEBPA CEBPE CEBPG CREB3 CREBBP DBP DDIT3 FGFR3 FOS FOSL1 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 ID3 IGSF21 JUN JUNB JUND LRIF1 MAFF MAFG MDM2 NFKB1 NUF2 PDX1 POLR3D SMAD3 SRA1 SS18L1 STAT1 SUMO1 SUMO3 SUV39H1 TP53 ZNF212
Entrez ID		55791	467
HPRD ID		17975	04395
Ensembl ID		ENSG00000121931	ENSG00000162772
Uniprot IDs		Q5T3J3	P18847
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Death Regulation Of Apoptotic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Gene Expression Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Protein Metabolic Process System Development Regulation Of Gene Expression Developmental Process Regulation Of Cellular Protein Metabolic Process RNA Metabolic Process Multicellular Organismal Development Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Anatomical Structure Development Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cell Death Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Response To Stimulus Nervous System Development Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Programmed Cell Death Macromolecule Biosynthetic Process Response To Organic Substance Cellular Metabolic Process Response To Stress Positive Regulation Of Apoptotic Process Response To Steroid Hormone Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus DNA-templated Transcription, Initiation Regulation Of Cell Cycle Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Organic Substance Regulation Of Cell Cycle	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Stress Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Cellular Metabolic Process Response To Organic Substance Regulation Of Cell Differentiation Response To External Stimulus Negative Regulation Of Cellular Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Defense Response Cellular Response To Organic Substance Cell Differentiation Immune System Process Histone H3-K9 Modification Developmental Process Rhythmic Process Regulation Of Cell Death Response To Biotic Stimulus
Tagcloud ?		aging apply characterizing composition dysfunctional enrich immunopurified involves isolation isotope labelling polypeptides pot1 qtip shelterin shelterins silac smchd1 states syndromes telomere telomeres telomeric tho tin2 tpp1 trf1 tumourigenesis validate	activating attenuation beneficial caat chop combating contributes diabetogenic dietary elevation elicited endoplasmic enhancer evoked fatty hdac1 hdac3 homologous islets lipotoxicity mimicked min6 ms palmitate preserving prevents reticulum saturated silencing
Tagcloud (Difference) ?		aging apply characterizing composition dysfunctional enrich immunopurified involves isolation isotope labelling polypeptides pot1 qtip shelterin shelterins silac smchd1 states syndromes telomere telomeres telomeric tho tin2 tpp1 trf1 tumourigenesis validate	activating attenuation beneficial caat chop combating contributes diabetogenic dietary elevation elicited endoplasmic enhancer evoked fatty hdac1 hdac3 homologous islets lipotoxicity mimicked min6 ms palmitate preserving prevents reticulum saturated silencing
Tagcloud (Intersection) ?