LRIF1 and NACA

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LRIF1	NACA
Description		ligand dependent nuclear receptor interacting factor 1	nascent polypeptide associated complex subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Barr Body Nucleus Nucleoplasm Chromosome Nuclear Matrix Centriolar Satellite	Nucleus Cytoplasm Nascent Polypeptide-associated Complex Extracellular Exosome
	Molecular Function	Protein Binding Nuclear Retinoic Acid Receptor Binding	DNA Binding Transcription Coactivator Activity Protein Binding Unfolded Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Dosage Compensation By Inactivation Of X Chromosome	Negative Regulation Of Transcription By RNA Polymerase II Cardiac Ventricle Development Translation Protein Targeting To Membrane Negative Regulation Of Striated Muscle Cell Apoptotic Process Protein Transport Wound Healing Skeletal Muscle Tissue Regeneration Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Skeletal Muscle Tissue Growth Regulation Of Skeletal Muscle Fiber Development Heart Trabecula Morphogenesis Negative Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways
Drugs
Diseases
GWAS		Bone mineral content ( 31790847) Intraocular pressure ( 30591961)	Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Asthma ( 31619474) Atrial fibrillation ( 29892015 30061737) Diastolic blood pressure ( 30224653) JT interval ( 29874175) QRS duration ( 30012220)
Interacting Genes		143 interacting genes: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BANP BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRACR2A CRADD CRCP CRCT1 CRIPTO DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FHL2 FOSL2 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 H3-4 HAP1 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NOC2L NR3C1 NRBP1 NTAQ1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR1C POLR2C POLR3F PPARG PQBP1 PRKAB2 PRKAR2A PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SNU13 SPATA18 SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSEN15 TSPAN6 UBE2V2 UNC119 VIM VPS26C WDR62 WWC1 ZNF24 ZNF410	17 interacting genes: APLP1 CCDC90B FADD FOS FUNDC2 IGSF21 JUN LRIF1 MDM2 PPP1R18 PTEN SMYD1 SPP1 TBP TXLNA UCHL5 ZHX1
Entrez ID		55791	4666
HPRD ID		17975	03137
Ensembl ID		ENSG00000121931	ENSG00000196531
Uniprot IDs		Q5T3J3	E9PAV3 Q13765
PDB IDs			3LKX 3MCB 3MCE 7QWQ 7QWR 7QWS 8P2K 9F1B 9F1C 9F1D 9FQ0
Enriched GO Terms of Interacting Partners?		Nucleus Nucleoplasm Protein Binding Cytoplasm Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Apoptotic Process Chromatin Binding Positive Regulation Of Programmed Cell Death Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Nuclear Receptor Activity Regulation Of Intracellular Signal Transduction Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Population Proliferation Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Cytosol Positive Regulation Of Apoptotic Process Nucleolus Negative Regulation Of Transcription By RNA Polymerase II Biological_process Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Development Negative Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Hemopoiesis Chromatin Organization Regulation Of Cell Differentiation Mononuclear Cell Differentiation Regulation Of Lymphocyte Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Signal Transduction Positive Regulation Of Fibroblast Proliferation DNA-directed RNA Polymerase Activity Positive Regulation Of Biosynthetic Process Chromatin Remodeling Regulation Of Cell Cycle Process Regulation Of DNA Repair Regulation Of Cell Cycle G1/S Phase Transition	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Factor AP-1 Complex Receptor Serine/threonine Kinase Binding Forebrain Morphogenesis Response To Steroid Hormone Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Regulation Of RNA Metabolic Process Synapse Maturation Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Response To Immobilization Stress Response To Muscle Stretch SMAD Protein Signal Transduction R-SMAD Binding Negative Regulation Of Neuron Projection Development Regulation Of Primary Metabolic Process Regulation Of Smooth Muscle Cell Proliferation Regulation Of Proteolysis Alpha-2B Adrenergic Receptor Binding Developmental Process Response To Mechanical Stimulus Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Medium-term Memory Integrated Stress Response Signaling Cellular Response To Prolactin RNA Polymerase II-specific DNA-binding Transcription Factor Binding Enzyme Binding Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Regulation Of Ubiquitin-dependent Protein Catabolic Process Response To Formaldehyde Cellular Response To Vitamin B1 Response To Cocaine Negative Regulation Of Cell Projection Organization Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of Proteolysis Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Axonogenesis Cell Death Apoptotic Process Cytosolic MRNA Polyadenylation Alpha-2C Adrenergic Receptor Binding Animal Organ Development Programmed Cell Death
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