LRIF1 and GSTM4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LRIF1	GSTM4
Description		ligand dependent nuclear receptor interacting factor 1	glutathione S-transferase mu 4
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Barr Body Nucleus Nucleoplasm Chromosome Nuclear Matrix Centriolar Satellite	Cytoplasm Cytosol
	Molecular Function	Protein Binding Nuclear Retinoic Acid Receptor Binding	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Protein Binding Transferase Activity Lyase Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Glutathione Binding
	Biological Process	Regulation Of DNA-templated Transcription Dosage Compensation By Inactivation Of X Chromosome	Lipid Metabolic Process Glutathione Metabolic Process Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Long-chain Fatty Acid Biosynthetic Process
Pathways			Glutathione conjugation Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
Drugs			Glutathione Glutathione sulfonic acid S-octylglutathione Glutathione disulfide gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine Deoxycholic acid 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane S-Hexylglutathione
Diseases
GWAS		Bone mineral content ( 31790847) Intraocular pressure ( 30591961)	Alcohol dependence ( 33290381) Seasonality and depression ( 30217971)
Interacting Genes		143 interacting genes: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BANP BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRACR2A CRADD CRCP CRCT1 CRIPTO DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FHL2 FOSL2 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 H3-4 HAP1 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NOC2L NR3C1 NRBP1 NTAQ1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR1C POLR2C POLR3F PPARG PQBP1 PRKAB2 PRKAR2A PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SNU13 SPATA18 SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSEN15 TSPAN6 UBE2V2 UNC119 VIM VPS26C WDR62 WWC1 ZNF24 ZNF410	10 interacting genes: APLP1 GSTM3 IGSF21 LRIF1 MED31 NELFCD TLE1 TP53 UNC119 ZBTB16
Entrez ID		55791	2948
HPRD ID		17975	00706
Ensembl ID		ENSG00000121931	ENSG00000168765
Uniprot IDs		Q5T3J3	A0A140VKE3 A6NNT0 Q03013
PDB IDs			4GTU
Enriched GO Terms of Interacting Partners?		Nucleus Nucleoplasm Protein Binding Cytoplasm Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Apoptotic Process Chromatin Binding Positive Regulation Of Programmed Cell Death Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Nuclear Receptor Activity Regulation Of Intracellular Signal Transduction Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Population Proliferation Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Cytosol Positive Regulation Of Apoptotic Process Nucleolus Negative Regulation Of Transcription By RNA Polymerase II Biological_process Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Development Negative Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Hemopoiesis Chromatin Organization Regulation Of Cell Differentiation Mononuclear Cell Differentiation Regulation Of Lymphocyte Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Signal Transduction Positive Regulation Of Fibroblast Proliferation DNA-directed RNA Polymerase Activity Positive Regulation Of Biosynthetic Process Chromatin Remodeling Regulation Of Cell Cycle Process Regulation Of DNA Repair Regulation Of Cell Cycle G1/S Phase Transition	Cellular Response To Norepinephrine Stimulus Alpha-2B Adrenergic Receptor Binding Regulation Of Primary Metabolic Process Cytosolic MRNA Polyadenylation Alpha-2C Adrenergic Receptor Binding Response To Norepinephrine System Development Central Nervous System Development Identical Protein Binding Developmental Process Nitrobenzene Metabolic Process Detoxification Of Nitrogen Compound Cellular Detoxification Of Nitrogen Compound Establishment Of Blood-nerve Barrier Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Pentose-phosphate Shunt Positive Regulation Of Thymocyte Apoptotic Process Response To Actinomycin D T Cell Proliferation Involved In Immune Response Negative Regulation Of Helicase Activity Transcription Repressor Complex Oxidative Stress-induced Premature Senescence Positive Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of G1 To G0 Transition PML Body Glucose Catabolic Process To Lactate Via Pyruvate Positive Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Fibroblast Proliferation Germ Cell Nucleus Cellular Response To Actinomycin D Negative Regulation Of Fibroblast Proliferation Regulation Of Transcription Initiation By RNA Polymerase II Germ-line Stem Cell Division Positive Regulation Of NK T Cell Differentiation Type 2 Angiotensin Receptor Binding Male Germ-line Stem Cell Asymmetric Division Negative Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation NELF Complex Regulation Of Macromolecule Metabolic Process Nuclear Matrix Alpha-2A Adrenergic Receptor Binding Histone Deacetylase Regulator Activity Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly
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