LRIF1 and APLP1

Number of citations of the paper that reports this interaction (PMID 15383276)
99

Data Source:
BioGRID (two hybrid)

		LRIF1	APLP1
Gene Name		ligand dependent nuclear receptor interacting factor 1	amyloid beta (A4) precursor-like protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Microtubule Organizing Center Actin Cytoskeleton Nuclear Matrix	Basement Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Retinoic Acid Receptor Binding	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	MRNA Polyadenylation Regulation Of Translation Endocytosis Apoptotic Process Cell Adhesion Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Nervous System Development Organ Morphogenesis Extracellular Matrix Organization Negative Regulation Of CAMP Biosynthetic Process Forebrain Development Cellular Response To Norepinephrine Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		129 interactors: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRADD CRCT1 DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 HAP1 HIST3H3 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NHP2L1 NOC2L NR3C1 NRBP1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR2C POLR3F PPARG PQBP1 PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TDGF1 TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSPAN6 UBE2V2 VIM WDR62 WWC1 ZNF24	43 interactors: ANXA7 APBB1 APBB3 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24
Entrez ID		55791	333
HPRD ID		17975	00102
Ensembl ID		ENSG00000121931	ENSG00000105290
Uniprot IDs		Q5T3J3	F5GZ08 P51693
PDB IDs			3PMR 3Q7G 3Q7L 3QMK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Death Regulation Of Apoptotic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Gene Expression Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Protein Metabolic Process System Development Regulation Of Gene Expression Developmental Process Regulation Of Cellular Protein Metabolic Process RNA Metabolic Process Multicellular Organismal Development Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Anatomical Structure Development Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cell Death Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Response To Stimulus Nervous System Development Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Programmed Cell Death Macromolecule Biosynthetic Process Response To Organic Substance Cellular Metabolic Process Response To Stress Positive Regulation Of Apoptotic Process Response To Steroid Hormone Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus DNA-templated Transcription, Initiation Regulation Of Cell Cycle Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Organic Substance Regulation Of Cell Cycle	Developmental Process Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Anatomical Structure Development Positive Regulation Of Protein Metabolic Process System Development Positive Regulation Of Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Multicellular Organismal Development Regulation Of Phosphorylation Response To Organic Substance Regulation Of Gene Expression Response To Copper Ion Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Process Regulation Of Cell Proliferation Positive Regulation Of Protein Phosphorylation Cellular Aromatic Compound Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Cell Death Regulation Of Kinase Activity Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Copper Ion Cellular Response To Growth Factor Stimulus Positive Regulation Of Programmed Cell Death Negative Regulation Of Growth Response To Growth Factor Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Growth Positive Regulation Of Cell Death Positive Regulation Of Phosphorylation Heterocycle Metabolic Process Response To Organic Cyclic Compound Digestive Tract Development Negative Regulation Of Cellular Metabolic Process Cell Cycle Arrest RNA Metabolic Process Response To Inorganic Substance Regulation Of Cell Cycle Digestive System Development Negative Regulation Of Cell Growth G1/S Transition Of Mitotic Cell Cycle
Tagcloud ?		aging apply characterizing composition dysfunctional enrich immunopurified involves isolation isotope labelling polypeptides pot1 qtip shelterin shelterins silac smchd1 states syndromes telomere telomeres telomeric tho tin2 tpp1 trf1 tumourigenesis validate	abundance allocated analyzing aplp2 app apparatus appsalpha attached compartments corresponds endosomal golgi homozygous immunopurification impacts knockout ko organellar pool presynaptic residing sv2 sv2a synaptic synaptogamin synaptophysin synaptotagmin vesicle zone
Tagcloud (Difference) ?		aging apply characterizing composition dysfunctional enrich immunopurified involves isolation isotope labelling polypeptides pot1 qtip shelterin shelterins silac smchd1 states syndromes telomere telomeres telomeric tho tin2 tpp1 trf1 tumourigenesis validate	abundance allocated analyzing aplp2 app apparatus appsalpha attached compartments corresponds endosomal golgi homozygous immunopurification impacts knockout ko organellar pool presynaptic residing sv2 sv2a synaptic synaptogamin synaptophysin synaptotagmin vesicle zone
Tagcloud (Intersection) ?