GADD45G and TRMT2A

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GADD45G	TRMT2A
Gene Name		growth arrest and DNA-damage-inducible, gamma	tRNA methyltransferase 2 homolog A (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Nucleotide Binding RNA Methyltransferase Activity Poly(A) RNA Binding
	Biological Process	Activation Of MAPKKK Activity Activation Of MAPKK Activity Negative Regulation Of Protein Kinase Activity Apoptotic Process Response To Stress Multicellular Organismal Development Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of P38MAPK Cascade	RNA Methylation RNA Processing
Pathways
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		55 interactors: AFAP1L1 APP ARPC5L CCNB1 CDK1 CDKN1A CEP57L1 CRIP2 DDAH2 EEF1A1 EEF1G EIF3G ESR1 EZH2 GADD45B GADD45GIP1 GDF9 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN PCNA PDE4DIP PDIA4 PHAX PIAS4 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RBM48 RDH13 REL RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579	14 interactors: AIMP2 ANXA7 APP ATP1B1 CDK4 CDKN1A GADD45G PIK3R3 PIN1 RASA1 RCC1 SMN1 TK1 TNFSF11
Entrez ID		10912	27037
HPRD ID		05383	13719
Ensembl ID		ENSG00000130222	ENSG00000099899
Uniprot IDs		O95257 Q5VZ87	Q8IZ69
PDB IDs		2WAL 3FFM
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Steroid Hormone Mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Cellular Response To Steroid Hormone Stimulus Cellular Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Ventricular Cardiac Muscle Cell Differentiation Hormone-mediated Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Death DNA-templated Transcription, Initiation Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Fibroblast Proliferation Response To Organic Cyclic Compound Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Response To Stress Cellular Response To Lipid Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Transcription, DNA-templated Cellular Response To Hormone Stimulus Positive Regulation Of Cellular Biosynthetic Process Regulation Of Catalytic Activity RNA Biosynthetic Process Regulation Of Kinase Activity Regulation Of Growth Response To Steroid Hormone Cellular Metabolic Process Positive Regulation Of Intracellular Signal Transduction	Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Cell Cycle Process Regulation Of Cell Cycle Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Calcium Ion Homeostasis Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Response To Hyperoxia Positive Regulation Of Protein Modification Process Metal Ion Homeostasis Response To Toxic Substance Developmental Process Positive Regulation Of Hydrolase Activity Response To Stress Positive Regulation Of Transferase Activity Ion Homeostasis Response To Organic Substance Regulation Of Mitotic Cell Cycle Phase Transition Response To Abiotic Stimulus Positive Regulation Of Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Multicellular Organismal Development Phosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Anatomical Structure Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Process Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Cellular Calcium Ion Homeostasis Positive Regulation Of Corticotropin-releasing Hormone Secretion Fetal Process Involved In Parturition Positive Regulation Of Protein Phosphorylation Positive Regulation Of Fibroblast Proliferation
Tagcloud ?		arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo
Tagcloud (Difference) ?		arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo
Tagcloud (Intersection) ?