GADD45G and RWDD2B

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		GADD45G	RWDD2B
Gene Name		growth arrest and DNA-damage-inducible, gamma	RWD domain containing 2B
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cellular_component
	Molecular Function	Protein Binding	Molecular_function
	Biological Process	Activation Of MAPKKK Activity Activation Of MAPKK Activity Negative Regulation Of Protein Kinase Activity Apoptotic Process Response To Stress Multicellular Organismal Development Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of P38MAPK Cascade	Biological_process
Pathways
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		55 interactors: AFAP1L1 APP ARPC5L CCNB1 CDK1 CDKN1A CEP57L1 CRIP2 DDAH2 EEF1A1 EEF1G EIF3G ESR1 EZH2 GADD45B GADD45GIP1 GDF9 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN PCNA PDE4DIP PDIA4 PHAX PIAS4 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RBM48 RDH13 REL RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579	13 interactors: APP BRCA1 DDX19B DNM2 DVL3 EPB41 GADD45G IKZF1 KIAA1958 KRT40 KRTAP10-7 PHC2 SRPK2
Entrez ID		10912	10069
HPRD ID		05383	10757
Ensembl ID		ENSG00000130222
Uniprot IDs		O95257 Q5VZ87	P57060
PDB IDs		2WAL 3FFM	2DAX
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Steroid Hormone Mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Cellular Response To Steroid Hormone Stimulus Cellular Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Ventricular Cardiac Muscle Cell Differentiation Hormone-mediated Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Death DNA-templated Transcription, Initiation Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Fibroblast Proliferation Response To Organic Cyclic Compound Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Response To Stress Cellular Response To Lipid Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Transcription, DNA-templated Cellular Response To Hormone Stimulus Positive Regulation Of Cellular Biosynthetic Process Regulation Of Catalytic Activity RNA Biosynthetic Process Regulation Of Kinase Activity Regulation Of Growth Response To Steroid Hormone Cellular Metabolic Process Positive Regulation Of Intracellular Signal Transduction	Positive Regulation Of Gene Expression Multicellular Organismal Development Positive Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Developmental Growth Positive Regulation Of Cellular Metabolic Process Developmental Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cell Cycle Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation Nuclear Speck Organization Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Multicellular Organism Growth Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Membrane Tubulation Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Collateral Sprouting In Absence Of Injury Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Protein Binding Regulation Of Growth Positive Regulation Of Cell Death Cellular Response To Indole-3-methanol Collateral Sprouting Axon Midline Choice Point Recognition Non-canonical Wnt Signaling Pathway Via JNK Cascade Regulation Of JNK Cascade Regulation Of Apoptotic Process Negative Regulation Of Centriole Replication Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Non-canonical Wnt Signaling Pathway Via MAPK Cascade Regulation Of Stress-activated MAPK Cascade Regulation Of Cell Death Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of NK T Cell Differentiation Axon Choice Point Recognition Regulation Of Protein Kinase Activity Intracellular Receptor Signaling Pathway Protein K6-linked Ubiquitination Activation Of MAPKKK Activity
Tagcloud ?		arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo
Tagcloud (Difference) ?		arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo
Tagcloud (Intersection) ?