GADD45G and TSNAX

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GADD45G	TSNAX
Gene Name		growth arrest and DNA-damage-inducible, gamma	translin-associated factor X
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	DNA Binding Single-stranded DNA Binding Endoribonuclease Activity Protein Transporter Activity Sequence-specific DNA Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Activation Of MAPKKK Activity Activation Of MAPKK Activity Negative Regulation Of Protein Kinase Activity Apoptotic Process Response To Stress Multicellular Organismal Development Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of P38MAPK Cascade	Multicellular Organismal Development Spermatogenesis Gene Expression Protein Transport Cell Differentiation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			Regulatory RNA pathways Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		55 interactors: AFAP1L1 APP ARPC5L CCNB1 CDK1 CDKN1A CEP57L1 CRIP2 DDAH2 EEF1A1 EEF1G EIF3G ESR1 EZH2 GADD45B GADD45GIP1 GDF9 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN PCNA PDE4DIP PDIA4 PHAX PIAS4 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RBM48 RDH13 REL RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579	22 interactors: AIMP1 AKAP9 BLOC1S5 C1D CARD9 CDK5RAP2 CKAP4 GADD45G GOLGA3 KCNE4 KLC3 LDB2 LZTS2 MRFAP1L1 NSMCE2 PBXIP1 RALYL SUMO1 SUN1 TCF12 TSN TSNAXIP1
Entrez ID		10912	7257
HPRD ID		05383	04270
Ensembl ID		ENSG00000130222	ENSG00000116918
Uniprot IDs		O95257 Q5VZ87	Q99598
PDB IDs		2WAL 3FFM	3PJA 3QB5
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Steroid Hormone Mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Cellular Response To Steroid Hormone Stimulus Cellular Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Ventricular Cardiac Muscle Cell Differentiation Hormone-mediated Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Death DNA-templated Transcription, Initiation Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Fibroblast Proliferation Response To Organic Cyclic Compound Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Response To Stress Cellular Response To Lipid Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Transcription, DNA-templated Cellular Response To Hormone Stimulus Positive Regulation Of Cellular Biosynthetic Process Regulation Of Catalytic Activity RNA Biosynthetic Process Regulation Of Kinase Activity Regulation Of Growth Response To Steroid Hormone Cellular Metabolic Process Positive Regulation Of Intracellular Signal Transduction	Protein Sumoylation Developmental Process Positive Regulation Of Cellular Metabolic Process Axon Cargo Transport Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Multicellular Organismal Development Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Cellular Localization Mitotic Cell Cycle Process
Tagcloud ?		arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo	bdi beadstation bipolar chinese disorder edition fourth genotyped genotyping goldengate guangzhou han haplotype haplotypes illumina lis1 lis1and machine manual meeting plink polymorphisms psychotic snp snps software statistic subgroups ten
Tagcloud (Difference) ?		arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo	bdi beadstation bipolar chinese disorder edition fourth genotyped genotyping goldengate guangzhou han haplotype haplotypes illumina lis1 lis1and machine manual meeting plink polymorphisms psychotic snp snps software statistic subgroups ten
Tagcloud (Intersection) ?