LRIF1 and HSPBP1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LRIF1	HSPBP1
Gene Name		ligand dependent nuclear receptor interacting factor 1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Microtubule Organizing Center Actin Cytoskeleton Nuclear Matrix
	Molecular Function	Protein Binding Retinoic Acid Receptor Binding	Enzyme Inhibitor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Protein Folding Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		129 interactors: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRADD CRCT1 DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 HAP1 HIST3H3 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NHP2L1 NOC2L NR3C1 NRBP1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR2C POLR3F PPARG PQBP1 PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TDGF1 TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSPAN6 UBE2V2 VIM WDR62 WWC1 ZNF24	10 interactors: APP HSPA1A HSPA1B HSPA2 HSPA4 HSPA5 HSPA8 HSPA9 LRIF1 NOTCH2NL
Entrez ID		55791	23640
HPRD ID		17975	09991
Ensembl ID		ENSG00000121931	ENSG00000133265
Uniprot IDs		Q5T3J3	Q9NZL4
PDB IDs			1XQR 1XQS
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Death Regulation Of Apoptotic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Gene Expression Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Protein Metabolic Process System Development Regulation Of Gene Expression Developmental Process Regulation Of Cellular Protein Metabolic Process RNA Metabolic Process Multicellular Organismal Development Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Anatomical Structure Development Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cell Death Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Response To Stimulus Nervous System Development Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Programmed Cell Death Macromolecule Biosynthetic Process Response To Organic Substance Cellular Metabolic Process Response To Stress Positive Regulation Of Apoptotic Process Response To Steroid Hormone Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus DNA-templated Transcription, Initiation Regulation Of Cell Cycle Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Organic Substance Regulation Of Cell Cycle	Response To Unfolded Protein Protein Refolding Negative Regulation Of Inclusion Body Assembly Regulation Of Inclusion Body Assembly Protein Folding Regulation Of Cellular Response To Heat Cellular Heat Acclimation Cellular Response To Heat Response To Heat Positive Regulation Of Erythrocyte Differentiation MRNA Metabolic Process Response To Temperature Stimulus Regulation Of Protein Ubiquitination Regulation Of Erythrocyte Differentiation Response To Stress Viral Entry Into Host Cell Entry Into Host Cell Response To Organic Substance Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Protein Targeting To Mitochondrion Negative Regulation Of Apoptotic Process Platelet Degranulation Negative Regulation Of Programmed Cell Death Protein Localization To Mitochondrion Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G2/M Transition Of Mitotic Cell Cycle Synaptonemal Complex Disassembly Negative Regulation Of Fibril Organization Regulation Of Protein Folding In Endoplasmic Reticulum Positive Regulation Of Myeloid Cell Differentiation Response To External Stimulus Cellular Protein Metabolic Process Negative Regulation Of Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Oxidative Stress Protein Stabilization Regulation Of Cellular Protein Metabolic Process Response To Abiotic Stimulus Establishment Of Localization In Cell Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Protein Ubiquitination Interaction With Host Cerebellum Structural Organization Synaptic Growth At Neuromuscular Junction Secretion By Cell Protein Localization To Organelle Regulation Of Protein Metabolic Process Locomotion Collateral Sprouting In Absence Of Injury Regulation Of Fibril Organization Viral Process
Tagcloud ?		aging apply characterizing composition dysfunctional enrich immunopurified involves isolation isotope labelling polypeptides pot1 qtip shelterin shelterins silac smchd1 states syndromes telomere telomeres telomeric tho tin2 tpp1 trf1 tumourigenesis validate	accelerating associates bag biogenesis cftr cochaperone compartments conductance cystic deltaf508 export fibrosis folding hsc70 hsp105 hsp105alpha impairing inform interferes misfolded misfolding multilevel opportunities phe potently relates serves stabilizes super
Tagcloud (Difference) ?		aging apply characterizing composition dysfunctional enrich immunopurified involves isolation isotope labelling polypeptides pot1 qtip shelterin shelterins silac smchd1 states syndromes telomere telomeres telomeric tho tin2 tpp1 trf1 tumourigenesis validate	accelerating associates bag biogenesis cftr cochaperone compartments conductance cystic deltaf508 export fibrosis folding hsc70 hsp105 hsp105alpha impairing inform interferes misfolded misfolding multilevel opportunities phe potently relates serves stabilizes super
Tagcloud (Intersection) ?