UTP14A and CEP70

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UTP14A	CEP70
Gene Name		UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	centrosomal protein 70kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Small-subunit Processome	Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Membrane
	Molecular Function	Protein Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Maturation Of SSU-rRNA	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: AKTIP APLP1 ARIH2 AXIN1 CCDC106 CCDC85B CEP70 CPE CSNK2A1 CSNK2B DLEU1 GADD45G HNRNPH3 HOOK2 HTT LAMTOR5 LDOC1 LSM3 NINL PDCD5 PDZK1IP1 PHF10 PRKCZ PSG1 PTEN PTPRS RABIF RGS1 RHOH RNF10 RPA2 RSRC1 SAT1 SMYD1 SSR1 TERF1 TINAGL1 TP53 TP53BP2 TRDMT1 VIM WDR33 ZNF24	134 interactors: ABT1 AKAP17A ARHGEF3 ATP5O ATXN7 BARD1 BEX2 BRMS1 BYSL C11orf57 C1orf35 C7orf25 C8orf33 CARD9 CCDC85B CCDC94 CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL DAZAP2 DDX41 DDX6 DIEXF DNAJB11 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM214B FAM64A GATAD2B GCC1 GPATCH2L GPATCH4 GPX7 HAUS1 HMGB4 HSPD1 IK IQCE KANK2 KANSL1 KAT7 KDM1A KRT31 LAMTOR5 LENG1 LENG8 LIN37 MCM10 MEST METTL17 MFAP1 MRPL44 NIPSNAP3A NKAP NOL12 NOP2 NRIP1 NUSAP1 PAM16 PLA2G2A PPFIA1 PPIG PPP1R16B PRKRIP1 PRPF31 PSMA1 RCOR3 RPL13 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TCEB3 TCEB3B TEAD4 TRIM29 TRIM42 TSGA10IP TSHZ3 TTC25 TTLL10 TXLNB UTP11L UTP14A ZBTB16 ZBTB24 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZGPAT ZNF136 ZNF148 ZNF169 ZNF227 ZNF239 ZNF266 ZNF302 ZNF329 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF439 ZNF490 ZNF555 ZNF572 ZNF578 ZNF587 ZSCAN12
Entrez ID		10813	80321
HPRD ID		06712	16779
Ensembl ID		ENSG00000156697	ENSG00000114107
Uniprot IDs		F8WD00 Q9BVJ6	B7Z2D2 Q8NHQ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Developmental Process Regulation Of Catalytic Activity Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Nervous System Development System Development Mitotic Cell Cycle Process Multicellular Organismal Development Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Positive Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Catalytic Activity Regulation Of Cell Cycle Phase Transition Regulation Of Metabolic Process Cell Cycle Positive Regulation Of Metabolic Process Response To Stimulus Positive Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Protein Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Protein Modification Process Negative Regulation Of Cell Proliferation Negative Regulation Of Neurogenesis Regulation Of Cell Cycle Cytoplasmic Transport Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Protein Phosphorylation Mitotic Cell Cycle Checkpoint Central Nervous System Development Negative Regulation Of Cell Differentiation Cell Differentiation Negative Regulation Of Cell Development Regulation Of Phosphorylation Neurotransmitter Uptake	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Ribonucleoprotein Complex Biogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process RRNA Processing Regulation Of Cellular Process RRNA Metabolic Process Ribosomal Small Subunit Biogenesis Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification MRNA Metabolic Process Metabolic Process Ribosome Biogenesis Histone H3-K9 Dimethylation RNA Processing Chromatin Organization Histone Modification Maturation Of SSU-rRNA Chromosome Organization Cell Death Death Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Apoptotic Process
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