UTP14A and SSR1

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		UTP14A	SSR1
Name		UTP14A small subunit processome component	signal sequence receptor subunit 1
Structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Small-subunit Processome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	RRNA Processing Ribosome Biogenesis	Cotranslational Protein Targeting To Membrane Positive Regulation Of Cell Population Proliferation
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes
GWAS		No GWAS studies recorded	Brain morphology (MOSTest) ( 32665545 ) Ewing sarcoma ( 30093639 ) Hip circumference adjusted for BMI ( 34021172 ) Spherical equivalent or myopia (age of diagnosis) ( 29808027 ) Subcortical volume (MOSTest) ( 32665545 ) Type 2 diabetes ( 24509480 28869590 30718926 32499647 )
Interacting Genes		54 interacting genes: AKTIP APLP1 APP ARIH2 AXIN1 BICD2 CCDC106 CCDC85B CEP70 CPE CSNK2A1 CSNK2B DLEU1 EXOSC8 GADD45G HNRNPH3 HOOK1 HOOK2 HTT KRT31 LAMTOR5 LDOC1 LMO1 LSM3 NIN NINL PDCD5 PDZK1IP1 PHF10 PRKCZ PSG1 PTEN PTPRS RABIF RGS1 RHOH RNF10 RPA2 RSRC1 SAT1 SMYD1 SNRNP48 SSR1 TERF1 TFIP11 TINAGL1 TP53 TP53BP2 TRDMT1 TXLNB USO1 VIM WDR33 ZNF24	8 interacting genes: DKC1 EEF1A1 HSPA13 NUP54 ODC1 PTN SERPINF2 UTP14A
Entrez ID		10813	6745
HPRD ID		06712	02924
Ensembl ID		ENSG00000156697	ENSG00000124783
Uniprot IDs		Q9BVJ6	C9JBX5 P43307
PDB IDs		7MQ8 7MQ9 7MQA 7WTS	8B6L
GO Terms Enriched among Interactors		FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm Microtubule Cytoskeleton Organization Microtubule Anchoring At Microtubule Organizing Center HOPS Complex MRNA Metabolic Process Identical Protein Binding Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body PML Body Cellular Response To Norepinephrine Stimulus Response To Norepinephrine Cellular Localization Organelle Organization Microtubule Anchoring Early Endosome To Late Endosome Transport P53 Binding Dynein Light Intermediate Chain Binding Apoptotic Process Positive Regulation Of Aggrephagy Central Nervous System Development Cytoplasm Programmed Cell Death Cell Death Positive Regulation Of Excitatory Postsynaptic Potential Fibrillar Center Microtubule-based Process Cytoskeleton Organization Microtubule Organizing Center Intracellular Transport Nucleus Cytoskeleton-dependent Intracellular Transport G-rich Strand Telomeric DNA Binding Cellular Response To Muramyl Dipeptide Modulation Of Excitatory Postsynaptic Potential Developmental Cell Growth Microtubule Anchoring At Centrosome Regulation Of Nervous System Process Endosome To Lysosome Transport Nuclear Matrix Supramolecular Fiber Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cell Cycle Negative Regulation Of Neurogenesis Centrosome Nucleoplasm Dynactin Binding Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Nervous System Development Cytoplasmic Microtubule Organization	None