UTP14A and RHOH

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UTP14A	RHOH
Gene Name		UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	ras homolog family member H
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Small-subunit Processome	Immunological Synapse Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Poly(A) RNA Binding	GTPase Inhibitor Activity Protein Binding GTP Binding Rho GTPase Binding Kinase Inhibitor Activity
	Biological Process	Maturation Of SSU-rRNA	Regulation Of Transcription, DNA-templated Small GTPase Mediated Signal Transduction T Cell Differentiation Negative Regulation Of Phosphorylation Negative Regulation Of Catalytic Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Mast Cell Activation Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS			Graves' disease ( 21841780)
Protein-Protein Interactions		43 interactors: AKTIP APLP1 ARIH2 AXIN1 CCDC106 CCDC85B CEP70 CPE CSNK2A1 CSNK2B DLEU1 GADD45G HNRNPH3 HOOK2 HTT LAMTOR5 LDOC1 LSM3 NINL PDCD5 PDZK1IP1 PHF10 PRKCZ PSG1 PTEN PTPRS RABIF RGS1 RHOH RNF10 RPA2 RSRC1 SAT1 SMYD1 SSR1 TERF1 TINAGL1 TP53 TP53BP2 TRDMT1 VIM WDR33 ZNF24	8 interactors: ARHGDIA ARHGDIB ARHGDIG GDI1 KCNH2 LRIF1 TGFBR1 UTP14A
Entrez ID		10813	399
HPRD ID		06712	03616
Ensembl ID		ENSG00000156697
Uniprot IDs		F8WD00 Q9BVJ6	Q15669 Q6ICP4
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Developmental Process Regulation Of Catalytic Activity Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Nervous System Development System Development Mitotic Cell Cycle Process Multicellular Organismal Development Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Positive Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Catalytic Activity Regulation Of Cell Cycle Phase Transition Regulation Of Metabolic Process Cell Cycle Positive Regulation Of Metabolic Process Response To Stimulus Positive Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Protein Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Protein Modification Process Negative Regulation Of Cell Proliferation Negative Regulation Of Neurogenesis Regulation Of Cell Cycle Cytoplasmic Transport Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Protein Phosphorylation Mitotic Cell Cycle Checkpoint Central Nervous System Development Negative Regulation Of Cell Differentiation Cell Differentiation Negative Regulation Of Cell Development Regulation Of Phosphorylation Neurotransmitter Uptake	Ras Protein Signal Transduction Rho Protein Signal Transduction Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Negative Regulation Of Cell Adhesion Positive Regulation Of Catalytic Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Regulation Of Protein Localization Regulation Of Intracellular Signal Transduction Negative Regulation Of Axonogenesis Positive Regulation Of Hydrolase Activity Negative Regulation Of Potassium Ion Export Regulation Of Cell Morphogenesis Regulation Of Catalytic Activity Regulation Of Cell Projection Organization Negative Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Heart Rate By Hormone Negative Regulation Of Neuron Projection Development Regulation Of Signal Transduction Regulation Of Cell Adhesion Negative Regulation Of Cell Projection Organization Regulation Of Axonogenesis Regulation Of Cellular Component Movement Negative Regulation Of Cell Differentiation Regulation Of Signaling Negative Regulation Of Neuron Differentiation Negative Regulation Of Protein Targeting To Membrane Signal Transduction Regulation Of Cell Development Positive Regulation Of Metabolic Process Parathyroid Gland Development Peptidyl-histidine Phosphorylation Regulation Of Heart Rate By Chemical Signal Signaling Regulation Of Intracellular Protein Transport Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Cell Communication Signal Transduction By Phosphorylation Positive Regulation Of Cell Projection Organization Potassium Ion Export Endothelial Cell Activation Negative Regulation Of Neurogenesis Pathway-restricted SMAD Protein Phosphorylation Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization Positive Regulation Of SMAD Protein Import Into Nucleus Negative Regulation Of Potassium Ion Transmembrane Transport
Tagcloud ?			ar autosomal broaden cutaneous deficiencies deficiency discovery epidermodysplasia ercc3 etiology ev ever1 ever2 exome fungal homozygous hpvs infections kindreds manifestations mst1 otherwise profound recessive siblings thirds tumoral unrelated verruciformis
Tagcloud (Difference) ?			ar autosomal broaden cutaneous deficiencies deficiency discovery epidermodysplasia ercc3 etiology ev ever1 ever2 exome fungal homozygous hpvs infections kindreds manifestations mst1 otherwise profound recessive siblings thirds tumoral unrelated verruciformis
Tagcloud (Intersection) ?