UTP14A and RHOH

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UTP14A	RHOH
Description		UTP14A small subunit processome component	ras homolog family member H
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Small-subunit Processome	Immunological Synapse Cytoplasm Plasma Membrane Membrane
	Molecular Function	RNA Binding Protein Binding	Nucleotide Binding GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Kinase Inhibitor Activity Protein Kinase Binding Small GTPase Binding
	Biological Process	RRNA Processing Ribosome Biogenesis	Regulation Of DNA-templated Transcription Actin Filament Organization Signal Transduction Small GTPase-mediated Signal Transduction T Cell Differentiation Negative Regulation Of Canonical NF-kappaB Signal Transduction Mast Cell Activation Positive Regulation Of T Cell Differentiation
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	RHOH GTPase cycle
Drugs
Diseases
GWAS			Graves' disease ( 21841780) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		54 interacting genes: AKTIP APLP1 APP ARIH2 AXIN1 BICD2 CCDC106 CCDC85B CEP70 CPE CSNK2A1 CSNK2B DLEU1 EXOSC8 GADD45G HNRNPH3 HOOK1 HOOK2 HTT KRT31 LAMTOR5 LDOC1 LMO1 LSM3 NIN NINL PDCD5 PDZK1IP1 PHF10 PRKCZ PSG1 PTEN PTPRS RABIF RGS1 RHOH RNF10 RPA2 RSRC1 SAT1 SMYD1 SNRNP48 SSR1 TERF1 TFIP11 TINAGL1 TP53 TP53BP2 TRDMT1 TXLNB USO1 VIM WDR33 ZNF24	23 interacting genes: ARHGDIA ARHGDIB ARHGDIG BANP CCNH FAM90A1 GDI1 IQUB ITGB1BP1 KANK2 KCNH2 LRIF1 MBLAC1 MTX2 PLEKHA7 RIPPLY1 SCNM1 SORL1 SUOX TCF19 TGFBR1 UTP14A XPNPEP1
Entrez ID		10813	399
HPRD ID		06712	03616
Ensembl ID		ENSG00000156697	ENSG00000168421
Uniprot IDs		Q9BVJ6	Q15669 Q6ICP4
PDB IDs		7MQ8 7MQ9 7MQA 7WTS
Enriched GO Terms of Interacting Partners?		FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm Microtubule Cytoskeleton Organization Microtubule Anchoring At Microtubule Organizing Center HOPS Complex MRNA Metabolic Process Identical Protein Binding Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body PML Body Cellular Response To Norepinephrine Stimulus Response To Norepinephrine Cellular Localization Organelle Organization Microtubule Anchoring Early Endosome To Late Endosome Transport P53 Binding Dynein Light Intermediate Chain Binding Apoptotic Process Positive Regulation Of Aggrephagy Central Nervous System Development Cytoplasm Programmed Cell Death Cell Death Positive Regulation Of Excitatory Postsynaptic Potential Fibrillar Center Microtubule-based Process Cytoskeleton Organization Microtubule Organizing Center Intracellular Transport Nucleus Cytoskeleton-dependent Intracellular Transport G-rich Strand Telomeric DNA Binding Cellular Response To Muramyl Dipeptide Modulation Of Excitatory Postsynaptic Potential Developmental Cell Growth Microtubule Anchoring At Centrosome Regulation Of Nervous System Process Endosome To Lysosome Transport Nuclear Matrix Supramolecular Fiber Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cell Cycle Negative Regulation Of Neurogenesis Centrosome Nucleoplasm Dynactin Binding Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Nervous System Development Cytoplasmic Microtubule Organization	Rho GDP-dissociation Inhibitor Activity GDP-dissociation Inhibitor Activity Negative Regulation Of Protein Targeting To Membrane Rho Protein Signal Transduction
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