UTP14A and RNF10

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UTP14A	RNF10
Gene Name		UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	ring finger protein 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Small-subunit Processome	Nucleus Cytoplasm
	Molecular Function	Protein Binding Poly(A) RNA Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transcription Regulatory Region DNA Binding
	Biological Process	Maturation Of SSU-rRNA	Transcription, DNA-templated Negative Regulation Of Schwann Cell Proliferation Positive Regulation Of Myelination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS			Type 1 diabetes nephropathy ( 23028342)
Protein-Protein Interactions		43 interactors: AKTIP APLP1 ARIH2 AXIN1 CCDC106 CCDC85B CEP70 CPE CSNK2A1 CSNK2B DLEU1 GADD45G HNRNPH3 HOOK2 HTT LAMTOR5 LDOC1 LSM3 NINL PDCD5 PDZK1IP1 PHF10 PRKCZ PSG1 PTEN PTPRS RABIF RGS1 RHOH RNF10 RPA2 RSRC1 SAT1 SMYD1 SSR1 TERF1 TINAGL1 TP53 TP53BP2 TRDMT1 VIM WDR33 ZNF24	28 interactors: CCDC90B COL4A5 EEF1A1 GRB2 KDM1A LRIF1 MDM2 SETDB1 SNCA TERF1 TLE1 TRIM26 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2J2 UBE2O UBE2U UBE2V1 UBE2W UBTD1 UTP14A
Entrez ID		10813	9921
HPRD ID		06712	11496
Ensembl ID		ENSG00000156697	ENSG00000022840
Uniprot IDs		F8WD00 Q9BVJ6	B3KWY9 Q8N5U6
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Developmental Process Regulation Of Catalytic Activity Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Nervous System Development System Development Mitotic Cell Cycle Process Multicellular Organismal Development Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Positive Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Catalytic Activity Regulation Of Cell Cycle Phase Transition Regulation Of Metabolic Process Cell Cycle Positive Regulation Of Metabolic Process Response To Stimulus Positive Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Protein Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Protein Modification Process Negative Regulation Of Cell Proliferation Negative Regulation Of Neurogenesis Regulation Of Cell Cycle Cytoplasmic Transport Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Protein Phosphorylation Mitotic Cell Cycle Checkpoint Central Nervous System Development Negative Regulation Of Cell Differentiation Cell Differentiation Negative Regulation Of Cell Development Regulation Of Phosphorylation Neurotransmitter Uptake	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Cellular Protein Modification Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Negative Regulation Of Chromosome Organization Protein Metabolic Process Protein Monoubiquitination Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Catabolic Process Innate Immune Response Toll-like Receptor 4 Signaling Pathway Cellular Response To Stress Proteolysis Regulation Of Chromosome Organization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Mitotic Cell Cycle Phase Transition Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Cell Cycle Phase Transition Toll-like Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Cellular Response To Oxygen Levels Mitotic Spindle Assembly Checkpoint Immune Response-regulating Signaling Pathway Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Transcription, DNA-templated Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Negative Regulation Of Chromosome Segregation Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of RNA Biosynthetic Process Activation Of Innate Immune Response Response To Stress Negative Regulation Of Mitotic Cell Cycle Phase Transition
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