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STAM2 and UBE2H
Number of citations of the paper that reports this interaction (PubMedID
17588522
)
0
Data Source:
BioGRID
(enzymatic study)
STAM2
UBE2H
Description
signal transducing adaptor molecule 2
ubiquitin conjugating enzyme E2 H
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Endosome
Cytosol
Membrane
Endocytic Vesicle
Early Endosome Membrane
ESCRT-0 Complex
Nucleus
Cytosol
Molecular Function
Protein Binding
Phosphatidylinositol Binding
Ubiquitin Binding
Nucleotide Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Transferase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Signal Transduction
Protein Transport
Macroautophagy
Multivesicular Body Assembly
Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Membrane Fission
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Pathways
EGFR downregulation
Ub-specific processing proteases
Negative regulation of MET activity
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
InlB-mediated entry of Listeria monocytogenes into host cell
RHOU GTPase cycle
Endosomal Sorting Complex Required For Transport (ESCRT)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Adverse response to chemotherapy in breast cancer (alopecia) (
24025145
)
Metabolic syndrome (
31170924
)
Pulse pressure (
30224653
)
Estimated glomerular filtration rate (
31152163
31451708
)
Lymphocyte count (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Monocyte count (
32888494
)
Response to antidepressants and depression (
27622933
)
White blood cell count (
32888494
)
Interacting Genes
37 interacting genes:
ABI2
ARRDC3
ATXN1
CBX5
CDC7
DAZAP2
EGFR
ENTREP1
EPS15
HGS
ITCH
JAK1
JAK2
JAK3
KLHL42
L3MBTL2
LCP2
LITAF
MAP3K1
PHF10
PLEKHB2
PTPN1
RNF11
SH2D4A
STAMBP
TIMM8A
TYK2
UBE2D1
UBE2D2
UBE2D3
UBE2H
UBQLN1
UBQLN4
USP8
VPS37C
XRN1
ZC3H10
71 interacting genes:
BRAP
CBLC
CD99
CDK2
DTX3
DTX3L
DZIP3
EPS15
GID4
GOLGA2
H2AC18
H2AC20
HBP1
HDAC6
JADE1
LNX2
LRSAM1
MAEA
MARCHF1
MARCHF10
MARCHF2
MARCHF4
MARCHF8
MDM2
MKRN3
NEURL1
NEURL2
NHLRC1
POLL
POLM
PRKN
PSME3
RAG1
RBX1
RELA
RNF10
RNF103
RNF113B
RNF114
RNF128
RNF133
RNF139
RNF144A
RNF146
RNF166
RNF185
RNF186
RNF2
RNF34
RNF38
RNF4
RNF6
STAM2
STUB1
TLE5
TRAIP
TRIM13
TRIM17
TRIM2
TRIM23
TRIM28
TRIM36
TRIM37
TRIM5
TRIM56
TRIM69
TRIM72
UBASH3B
UBOX5
UBR2
UBR3
Entrez ID
10254
7328
HPRD ID
05876
03052
Ensembl ID
ENSG00000115145
ENSG00000186591
Uniprot IDs
O75886
A0A3B3IU20
A4D1L5
P62256
PDB IDs
1X2Q
1X5B
2L0T
5CRV
5IXF
2Z5D
8PJN
Enriched GO Terms of Interacting Partners
?
Endosome
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Growth Hormone Receptor Signaling Pathway
Growth Hormone Receptor Binding
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Modification Process
Proteolysis Involved In Protein Catabolic Process
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Early Endosome
Proteolysis
Cell Surface Receptor Signaling Pathway Via STAT
Extrinsic Component Of Plasma Membrane
Ubiquitin Conjugating Enzyme Activity
Macromolecule Catabolic Process
Protein Metabolic Process
Non-membrane Spanning Protein Tyrosine Kinase Activity
Protein K48-linked Ubiquitination
Protein-containing Complex
Cytoplasmic Side Of Plasma Membrane
Negative Regulation Of Signal Transduction
Early Endosome Membrane
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Type II Interferon-mediated Signaling Pathway
Regulation Of Primary Metabolic Process
Regulation Of Protein Modification Process
Negative Regulation Of Cell Communication
Protein Tyrosine Kinase Activity
Negative Regulation Of Signaling
Post-translational Protein Modification
Regulation Of Macromolecule Metabolic Process
Regulation Of Protein Metabolic Process
Interleukin-12 Receptor Complex
Ubiquitin-protein Transferase Activity
Protein Autoubiquitination
Receptor Internalization
Regulation Of Receptor Signaling Pathway Via JAK-STAT
Positive Regulation Of Macromolecule Metabolic Process
Catabolic Process
Interleukin-23 Receptor Complex
Cytosol
Protein Polyubiquitination
Endosome Membrane
Regulation Of Metabolic Process
Enzyme-linked Receptor Protein Signaling Pathway
Proteasomal Protein Catabolic Process
Interleukin-23-mediated Signaling Pathway
Positive Regulation Of NK T Cell Proliferation
CXCL12-activated CXCR4 Signaling Pathway
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Post-translational Protein Modification
Transferase Activity
Protein Modification Process
Zinc Ion Binding
Protein Metabolic Process
Protein Polyubiquitination
Metal Ion Binding
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Protein Autoubiquitination
Macromolecule Metabolic Process
Macromolecule Catabolic Process
Proteolysis
Protein Catabolic Process
Catabolic Process
Proteasomal Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Ubiquitin Ligase Complex
Protein Monoubiquitination
Ubiquitin Protein Ligase Binding
Protein K63-linked Ubiquitination
Autophagy
Positive Regulation Of Catabolic Process
Cytoplasm
Endoplasmic Reticulum Mannose Trimming
Protein K48-linked Ubiquitination
Regulation Of Protein Catabolic Process
Protein Alpha-1,2-demannosylation
Suppression Of Viral Release By Host
Immune System Process
Protein Deglycosylation
Aggresome Assembly
Innate Immune Response
Positive Regulation Of Protein Catabolic Process
ERAD Pathway
Endoplasmic Reticulum Quality Control Compartment
Cellular Response To Stress
Protein K6-linked Ubiquitination
Ubiquitin Binding
Inclusion Body Assembly
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Autophagy
Aggresome
Defense Response To Symbiont
Defense Response To Other Organism
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Tagcloud (Difference)
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Tagcloud (Intersection)
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