TOPORS and TOP1

  • Number of citations of the paper that reports this interaction (PMID 10352183)
  • 13
  • Data Source:
  • HPRD (two hybrid, in vivo, in vitro)

TOPORS

TOP1

Gene Name topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase topoisomerase (DNA) I
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Immune response to smallpox vaccine (IL-6) ( 22610502)
Protein-Protein Interactions 24 interactors: CASP8 H2AFX HABP4 MTDH NKX3-1 SATB1 SERBP1 SIN3A SNIP1 SUMO1 SUMO2 TOP1 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2I UBE2J1 UBE2L6 UBE2N UBE2W 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I
Entrez ID 10210 7150
HPRD ID 11642 00535
Ensembl ID ENSG00000197579 ENSG00000198900
Uniprot IDs Q9NS56 P11387
PDB IDs 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bindingprotein  blockade  condition  deprivation  diphosphate  e3  eliminates  ern1  finction  finger  glioma  glutamine  matrin  nm23  nme  nme6  nucleoside  ofrybpi  oftumor  regulatedpa26  rybp  sesn1  tp53  tp53bp1  tp53bpi  tp53tg1  u87  zmat3 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Difference) ?
bindingprotein  blockade  condition  deprivation  diphosphate  e3  eliminates  ern1  finction  finger  glioma  glutamine  matrin  nm23  nme  nme6  nucleoside  ofrybpi  oftumor  regulatedpa26  rybp  sesn1  tp53  tp53bp1  tp53bpi  tp53tg1  u87  zmat3 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Intersection) ?
topoisomerase