HNRNPDL and ERG

Number of citations of the paper that reports this interaction (PMID 21575865)
67

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		HNRNPDL	ERG
Gene Name		heterogeneous nuclear ribonucleoprotein D-like	v-ets avian erythroblastosis virus E26 oncogene homolog
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Extracellular Vesicular Exosome	Nucleus Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Poly(A) Binding Poly(G) Binding Poly(A) RNA Binding	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Signal Transducer Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing Regulation Of Gene Expression	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Phosphorylation Signal Transduction Multicellular Organismal Development Cell Proliferation Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Metabolite levels (HVA) ( 23319000) Neonatal lupus ( 20662065) White blood cell types ( 21738478)
Protein-Protein Interactions		6 interactors: CSNK2A1 ERG HGS HMGA1 IL7R LRP1	61 interactors: ACTB ADAR APP CDC5L CLTC DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 FBL FLI1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 ILF2 ILF3 JUN LANCL1 MATR3 NCL NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 POLR2A PRKDC PRPF40A PRPF8 PUF60 RCC2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SNRNP200 SPI1 SYN1 TOP1 TOP2B USP9X XRN2
Entrez ID		9987	2078
HPRD ID		06185	01298
Ensembl ID		ENSG00000152795	ENSG00000157554
Uniprot IDs		O14979	B4DN83 B4DVX5 P11308
PDB IDs			1SXE 4IRG 4IRH 4IRI
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Potassium Ion Export Beta-amyloid Clearance Cellular Response To Stimulus Interleukin-7-mediated Signaling Pathway Oncogene-induced Cell Senescence Regulation Of Heart Rate By Hormone Cell Proliferation Positive Regulation Of Transport Senescence-associated Heterochromatin Focus Assembly Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Positive Regulation Of Cellular Senescence Regulation Of Metabolic Process Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of Chromatin Silencing Response To Stimulus Establishment Of Integrated Proviral Latency Regulation Of Gene Expression Positive Regulation Of Cell Aging Establishment Of Viral Latency Regulation Of Heart Rate By Chemical Signal Regulation Of Wnt Signaling Pathway Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Peptidyl-histidine Phosphorylation Signal Transduction Aging Potassium Ion Export Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Heterochromatin Assembly Protein Targeting To Lysosome Regulation Of Phospholipase A2 Activity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Developmental Process Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization DNA Unwinding Involved In DNA Replication Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of Potassium Ion Transmembrane Transport Protein Localization To Lysosome Potassium Ion Homeostasis Cell Surface Receptor Signaling Pathway Signaling Nucleosome Disassembly Lymph Node Development Heterochromatin Organization Regulation Of Protein Catabolic Process Cell Communication Positive Regulation Of T Cell Differentiation In Thymus Phosphorelay Signal Transduction System	MRNA Processing RNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Metabolic Process Osteoblast Differentiation Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Protein Refolding Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Ribosome Biogenesis Chromosome Organization Ossification Cis Assembly Of Pre-catalytic Spliceosome DNA Metabolic Process Regulation Of MRNA Stability Cell Differentiation Rhythmic Process Developmental Process Regulation Of RNA Stability Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Cellular Process Negative Regulation Of Cellular Metabolic Process MRNA Stabilization Negative Regulation Of Transcription, DNA-templated Circadian Rhythm Ribonucleoprotein Complex Assembly
Tagcloud ?			antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Difference) ?			antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Intersection) ?