HNRNPDL and LRP1

Number of citations of the paper that reports this interaction (PMID 20205790)
0

Data Source:
BioGRID (two hybrid)

		HNRNPDL	LRP1
Gene Name		heterogeneous nuclear ribonucleoprotein D-like	low density lipoprotein receptor-related protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Extracellular Vesicular Exosome	Nucleolus Cytoplasm Lysosomal Membrane Endosome Plasma Membrane Integral Component Of Plasma Membrane Coated Pit Focal Adhesion Clathrin-coated Vesicle Dendrite Endocytic Vesicle Membrane Neuronal Cell Body Receptor Complex
	Molecular Function	Nucleotide Binding DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Poly(A) Binding Poly(G) Binding Poly(A) RNA Binding	Protease Binding Receptor Activity Calcium Ion Binding Protein Binding Protein Complex Binding Apolipoprotein Binding Lipoprotein Transporter Activity Poly(A) RNA Binding Lipoprotein Particle Receptor Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing Regulation Of Gene Expression	Retinoid Metabolic Process Receptor-mediated Endocytosis Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Aging Phototransduction, Visible Light Cholesterol Metabolic Process Cell Proliferation Positive Regulation Of Cholesterol Efflux Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Lipid Transport Regulation Of Cholesterol Transport Regulation Of Phospholipase A2 Activity Regulation Of Actin Cytoskeleton Organization Aorta Morphogenesis Lipoprotein Metabolic Process Lipoprotein Transport Apoptotic Cell Clearance Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Protein Transport Beta-amyloid Clearance Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Pathways			Scavenging of heme from plasma Visual phototransduction Diseases associated with visual transduction Retinoid metabolism and transport
Drugs
Diseases
GWAS			Abdominal aortic aneurysm ( 22055160) HDL cholesterol ( 20686565) Migraine ( 22683712 21666692) Pulmonary function ( 21946350) Pulmonary function (interaction) ( 23284291) Triglycerides ( 20686565)
Protein-Protein Interactions		6 interactors: CSNK2A1 ERG HGS HMGA1 IL7R LRP1	63 interactors: A2M ANAPC10 ANKS1B APBA2 APBB1 APOE APP BACE1 C3 C4BPA CACNA1A CALR CANX CAV1 CC2D1A CD82 CTGF CTSG DAB1 DAB2 DLG4 ELANE F8 F9 FURIN GIPC1 GTPBP1 GULP1 HNRNPDL HSP90B1 ITGB1BP1 KAT5 LIPC LPL LRPAP1 LTF MAPK8IP1 MAPK8IP2 MAPRE1 MDK MMP13 MMP14 MMP15 MMP16 MMP17 NOS1AP PDGFB PID1 PLAT PLAUR PRKACA RIC8B SCN3A SERPINA1 SERPINE1 SHC1 SKIL SNRNP70 SNX17 SRC SYNJ2BP THBS1 WNT3A
Entrez ID		9987	4035
HPRD ID		06185	00138
Ensembl ID		ENSG00000152795	ENSG00000123384
Uniprot IDs		O14979	Q07954 Q59FG2
PDB IDs			1CR8 1D2L 1J8E 2FYJ 2FYL 2KNX 2KNY
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Potassium Ion Export Beta-amyloid Clearance Cellular Response To Stimulus Interleukin-7-mediated Signaling Pathway Oncogene-induced Cell Senescence Regulation Of Heart Rate By Hormone Cell Proliferation Positive Regulation Of Transport Senescence-associated Heterochromatin Focus Assembly Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Positive Regulation Of Cellular Senescence Regulation Of Metabolic Process Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of Chromatin Silencing Response To Stimulus Establishment Of Integrated Proviral Latency Regulation Of Gene Expression Positive Regulation Of Cell Aging Establishment Of Viral Latency Regulation Of Heart Rate By Chemical Signal Regulation Of Wnt Signaling Pathway Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Peptidyl-histidine Phosphorylation Signal Transduction Aging Potassium Ion Export Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Heterochromatin Assembly Protein Targeting To Lysosome Regulation Of Phospholipase A2 Activity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Developmental Process Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization DNA Unwinding Involved In DNA Replication Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of Potassium Ion Transmembrane Transport Protein Localization To Lysosome Potassium Ion Homeostasis Cell Surface Receptor Signaling Pathway Signaling Nucleosome Disassembly Lymph Node Development Heterochromatin Organization Regulation Of Protein Catabolic Process Cell Communication Positive Regulation Of T Cell Differentiation In Thymus Phosphorelay Signal Transduction System	Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Protein Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Catalytic Activity Regulation Of Proteolysis Negative Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Signaling Positive Regulation Of Protein Modification Process Regulation Of Signal Transduction Response To Wounding Regulation Of Protein Phosphorylation Blood Coagulation Hemostasis Regulation Of Protein Kinase Activity Response To Stress Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Endocytosis Negative Regulation Of Cellular Metabolic Process Response To Lipid Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Platelet Activation Regulation Of Phosphorylation Positive Regulation Of Transferase Activity Positive Regulation Of Protein Kinase Activity Regulation Of Body Fluid Levels Positive Regulation Of Kinase Activity Positive Regulation Of Signal Transduction Wound Healing Regulation Of Protein Processing Vesicle-mediated Transport Positive Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Negative Regulation Of Protein Processing Locomotion Extracellular Matrix Disassembly Regulation Of Protein Binding Regulation Of Vesicle-mediated Transport Regulation Of Blood Coagulation Anatomical Structure Morphogenesis Response To Stimulus Secretion By Cell
Tagcloud ?			aacr an2 ang4043 angiopep bbb biologics bt confers conjugate conjugated conjugation crosses endows entity extending implanted indications intracarotid intracranially kin mab neuro penetrant penetrates penetration retains systemically ther transcytosis
Tagcloud (Difference) ?			aacr an2 ang4043 angiopep bbb biologics bt confers conjugate conjugated conjugation crosses endows entity extending implanted indications intracarotid intracranially kin mab neuro penetrant penetrates penetration retains systemically ther transcytosis
Tagcloud (Intersection) ?