TCAF1 and SF3B4

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		TCAF1	SF3B4
Gene Name		TRPM8 channel-associated factor 1	splicing factor 3b, subunit 4, 49kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex
	Molecular Function		Nucleotide Binding Protein Binding Poly(A) RNA Binding
	Biological Process		RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Height ( 20881960 18391951)
Protein-Protein Interactions		11 interactors: COIL EFEMP2 IKZF3 SF3B4 SPRY2 TCF3 TFIP11 TRIP6 ZNF24 ZNF263 ZNF592	42 interactors: APBB1 BAG3 BAIAP2 BMPR1A CHERP CWF19L2 DDX17 DDX42 EFTUD2 EWSR1 FKBP1A FRK GRB2 HNRNPD HNRNPF HNRNPH1 HNRNPUL1 HSPB7 ILF3 ITSN1 MAPK9 METTL17 NCK2 NUB1 PPP1R16B PRPF40A RBM39 RBM4 SEC24D SF1 SF3B2 SRSF6 SS18L1 STK19 SUMO4 TCAF1 TCERG1 UBASH3A UBC WBP4 WDR77 ZCCHC10
Entrez ID		9747	10262
HPRD ID		13813	12028
Ensembl ID		ENSG00000198420	ENSG00000143368
Uniprot IDs		B4DST7 Q9Y4C2	B3KUJ0 Q15427
PDB IDs			1X5T 1X5U
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of B Cell Proliferation Spliceosomal Complex Disassembly Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Mesoderm Development B Cell Activation Release Of Cytoplasmic Sequestered NF-kappaB Axial Mesoderm Morphogenesis Immunoglobulin V(D)J Recombination Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Lung Growth Regulation Of Neurotrophin TRK Receptor Signaling Pathway Axial Mesoderm Development MRNA Splicing, Via Spliceosome Tissue Development RNA Splicing, Via Transesterification Reactions B Cell Lineage Commitment Bud Elongation Involved In Lung Branching Peyer's Patch Development Cell Fate Commitment Biosynthetic Process Negative Regulation Of Peptidyl-threonine Phosphorylation Natural Killer Cell Differentiation Negative Regulation Of Cellular Metabolic Process Anterior/posterior Axis Specification, Embryo Negative Regulation Of Ras GTPase Activity RNA Splicing Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of NF-kappaB Import Into Nucleus Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process	RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Regulation Of Gene Expression Circadian Regulation Of Translation Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Development Cellular Response To Growth Factor Stimulus Regulation Of ERBB Signaling Pathway Response To Growth Factor Negative Regulation Of Protein Metabolic Process Immune System Process Response To External Stimulus Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Development Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Signal Transduction Regulation Of Cellular Process Stress-activated MAPK Cascade Fc Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process
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