TCAF1 and ZNF592

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		TCAF1	ZNF592
Name		TRPM8 channel associated factor 1	zinc finger protein 592
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus
	Molecular Function	Protein Binding Transmembrane Transporter Binding	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding PH Domain Binding Insulin Receptor Substrate Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Migration Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Anion Channel Activity	Regulation Of DNA-templated Transcription Negative Regulation Of Insulin Receptor Signaling Pathway
Diseases		None	Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		No GWAS studies recorded	Alzheimer's disease (age of onset) ( 22005931 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Bipolar disorder ( 31043756 33263727 34002096 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Electrocardiographic traits (multivariate) ( 32602732 ) Hypertrophic cardiomyopathy ( 33495596 ) Hypertrophic cardiomyopathy (MTAG) ( 33495596 ) Schizophrenia ( 29483656 )
Interacting Genes		36 interacting genes: BIRC2 CAMK2A CEP70 CNKSR1 COIL CYSRT1 DISC1 EFEMP2 IKZF3 IKZF4 KRTAP1-3 KRTAP10-8 KRTAP13-2 KRTAP6-3 MAD1L1 MID2 NBPF19 NFYA PRDM14 PRDM6 RBAK SCYL3 SF3B4 SPRY2 TAX1BP1 TCF3 TFIP11 TRAF2 TRIM42 TRIM54 TRIP6 UBC ZNF143 ZNF24 ZNF263 ZNF592	6 interacting genes: BTG3 GRIK1 LAMTOR5 SMAD9 SRPK2 TCAF1
Entrez ID		9747	9640
HPRD ID		13813	10339
Ensembl ID		ENSG00000198420	ENSG00000166716
Uniprot IDs		B4DST7 Q9Y4C2	Q92610
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Zinc Ion Binding Identical Protein Binding	None