RIMS2 and YWHAH

Number of citations of the paper that reports this interaction (PubMedID 12871946)
0

Data Source:
HPRD (in vitro)

		RIMS2	YWHAH
Description		regulating synaptic membrane exocytosis 2	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Presynaptic Membrane Cell Projection Synapse Presynaptic Active Zone Extracellular Exosome Presynaptic Active Zone Cytoplasmic Component	Cytoplasm Mitochondrion Cytosol Plasma Membrane Intercalated Disc Synapse Extracellular Exosome Presynapse Glutamatergic Synapse Cerebellar Granule Cell To Purkinje Cell Synapse
	Molecular Function	Protein Binding Zinc Ion Binding Small GTPase Binding Transmembrane Transporter Binding Metal Ion Binding Structural Constituent Of Presynaptic Active Zone	Actin Binding Insulin-like Growth Factor Receptor Binding Protein Binding Sodium Channel Regulator Activity Enzyme Binding Protein Domain Specific Binding Nuclear Glucocorticoid Receptor Binding Identical Protein Binding Transmembrane Transporter Binding Protein Heterodimerization Activity
	Biological Process	Intracellular Protein Transport Exocytosis Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Synaptic Vesicle Docking Synaptic Vesicle Priming Calcium-ion Regulated Exocytosis Regulation Of Exocytosis Insulin Secretion Cell Differentiation Regulation Of Membrane Potential Maintenance Of Presynaptic Active Zone Structure Calcium Ion-regulated Exocytosis Of Neurotransmitter Spontaneous Neurotransmitter Secretion Positive Regulation Of Inhibitory Postsynaptic Potential Positive Regulation Of Dendrite Extension Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Excitatory Postsynaptic Potential	Regulation Of Sodium Ion Transport Glucocorticoid Catabolic Process Intracellular Protein Transport Signal Transduction Intracellular Protein Localization Substantia Nigra Development Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Regulation Of Neuron Differentiation Positive Regulation Of DNA-templated Transcription Regulation Of Synaptic Plasticity Negative Regulation Of Dendrite Morphogenesis Membrane Depolarization During Action Potential Presynaptic Modulation Of Chemical Synaptic Transmission
Pathways			Activation of BAD and translocation to mitochondria Translocation of SLC2A4 (GLUT4) to the plasma membrane RHO GTPases activate PKNs TP53 Regulates Metabolic Genes Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex SARS-CoV-1 targets host intracellular signalling and regulatory pathways SARS-CoV-2 targets host intracellular signalling and regulatory pathways Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Cocaine dependence ( 23958962) Dietary fat liking ( 32516399) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) High density lipoprotein cholesterol levels ( 30498476) Monoclonal gammopathy of undetermined significance ( 30737484) Multiple system atrophy (pathologically confirmed) ( 27629089) Parkinson's disease progression (cognitive) ( 33958783)	Post bronchodilator FEV1 ( 26634245) Type 2 diabetes ( 30297969)
Interacting Genes		13 interacting genes: ABCA1 CACNA1S EGFR RAB27A RAB3A RAB3B RAB3C RAB3D RAB8A RABAC1 RAPGEF4 RPH3AL YWHAH	69 interacting genes: ABL1 ARHGEF28 BAD BCR BRAF CCDC125 CDC25B CDC25C CDC42 CDK16 CDKN1B CHRNA4 CREBBP EPB41L2 EPB41L3 ESR1 ESR2 EXO1 GREM1 HSPB1 ILF3 ING1 KANK1 KCNH2 KCNK15 KCNK3 KCNK9 KLC3 KRT18 MAP3K3 MAP3K5 MARK4 MDM4 MED1 MST1R NCAM2 NCOA1 NCOA2 NCOA3 NEDD4L NEK1 NHSL2 NR3C1 NRIP1 PARD3 PARD6A PARD6B PCNT PDPK1 PRKCI PRKN PTH1R RAF1 REM1 RIMS1 RIMS2 RPH3A SAMSN1 SNCA SRC THRA TLX2 TNFAIP3 TPH1 TSC1 TSC2 YWHAE YWHAG ZFP36
Entrez ID		9699	7533
HPRD ID		09436	00215
Ensembl ID		ENSG00000176406	ENSG00000128245
Uniprot IDs		A0A8Q3SIU4 A0A8Q3SJ53 A0A994J503 A0A994J5M6 A0A994J7W6 F8W6W8 Q9UQ26	Q04917 Q9H4N8
PDB IDs		1V27 1WFG	2C63 2C74 7NMZ
Enriched GO Terms of Interacting Partners?		Myosin V Binding Exocytosis Secretion By Cell Secretion Regulation Of Exocytosis Establishment Of Protein Localization Synaptic Vesicle Protein Transport GTP-dependent Protein Binding Endosome Positive Regulation Of Regulated Secretory Pathway Regulation Of Transport Vesicle-mediated Transport GTPase Activity Regulation Of Vesicle-mediated Transport Regulation Of Secretion By Cell Intracellular Protein Localization GTP Binding Regulation Of Secretion Positive Regulation Of Exocytosis Positive Regulation Of Transport Nucleotide Binding Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Regulation Of Regulated Secretory Pathway Positive Regulation Of Secretion By Cell Positive Regulation Of Secretion Plasma Membrane Membrane Peptide Secretion GDP Binding Presynapse Golgi Apparatus Regulation Of Synaptic Vesicle Cycle Peptide Transport Antigen Processing And Presentation Small GTPase Binding Regulation Of Biological Quality Secretory Granule Regulated Exocytosis Vesicle Organization Intracellular Vesicle Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Perinuclear Region Of Cytoplasm Amide Transport Signal Release Calcium-ion Regulated Exocytosis Regulation Of Vesicle Fusion Synaptic Vesicle Transport	Intracellular Signal Transduction Nuclear Receptor-mediated Signaling Pathway Cytosol Regulation Of Cell Communication Regulation Of Signaling Regulation Of Programmed Cell Death Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Developmental Process Regulation Of Biological Quality PAR Polarity Complex Regulation Of Intracellular Signal Transduction Regulation Of Transport Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Protein Phosphorylation Regulation Of Membrane Potential Regulation Of Apoptotic Process Regulation Of Vesicle-mediated Transport Cell Junction Organization Negative Regulation Of Apoptotic Process Phosphorylation Positive Regulation Of Metabolic Process Enzyme Binding Negative Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Metabolic Process Regulation Of Multicellular Organismal Process Response To Lipid Cellular Response To Hormone Stimulus Hormone-mediated Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Developmental Process Positive Regulation Of Protein Localization Protein Kinase Binding Regulation Of Anatomical Structure Morphogenesis Developmental Process Cytoskeleton Organization Cellular Response To Lipid Positive Regulation Of Intracellular Signal Transduction Regulation Of Secretion By Cell Regulation Of Phosphorus Metabolic Process Regulation Of Protein Localization Positive Regulation Of Biosynthetic Process Protein Serine/threonine Kinase Activity Synaptic Vesicle Priming Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Protein Kinase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?