RIMS2 and RAB3C

Number of citations of the paper that reports this interaction (PubMedID 12578829)
0

Data Source:
HPRD (in vitro)

		RIMS2	RAB3C
Description		regulating synaptic membrane exocytosis 2	RAB3C, member RAS oncogene family
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GO Annotations	Cellular Component	Plasma Membrane Membrane Presynaptic Membrane Cell Projection Synapse Presynaptic Active Zone Extracellular Exosome Presynaptic Active Zone Cytoplasmic Component	Endosome Plasma Membrane Synaptic Vesicle Membrane Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Small GTPase Binding Transmembrane Transporter Binding Metal Ion Binding Structural Constituent Of Presynaptic Active Zone	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GTP-dependent Protein Binding Myosin V Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Exocytosis Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Synaptic Vesicle Docking Synaptic Vesicle Priming Calcium-ion Regulated Exocytosis Regulation Of Exocytosis Insulin Secretion Cell Differentiation Regulation Of Membrane Potential Maintenance Of Presynaptic Active Zone Structure Calcium Ion-regulated Exocytosis Of Neurotransmitter Spontaneous Neurotransmitter Secretion Positive Regulation Of Inhibitory Postsynaptic Potential Positive Regulation Of Dendrite Extension Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Excitatory Postsynaptic Potential	Exocytosis Protein Transport Regulation Of Exocytosis Antigen Processing And Presentation
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS		Cocaine dependence ( 23958962) Dietary fat liking ( 32516399) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) High density lipoprotein cholesterol levels ( 30498476) Monoclonal gammopathy of undetermined significance ( 30737484) Multiple system atrophy (pathologically confirmed) ( 27629089) Parkinson's disease progression (cognitive) ( 33958783)	Breast cancer ( 23535729 29059683) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Perceived intensity of sweet substances ( 31005972) Sleep duration (long sleep) ( 30846698)
Interacting Genes		13 interacting genes: ABCA1 CACNA1S EGFR RAB27A RAB3A RAB3B RAB3C RAB3D RAB8A RABAC1 RAPGEF4 RPH3AL YWHAH	7 interacting genes: CRYAA FKBP2 RABIF REP15 RIMS2 RPH3AL VRTN
Entrez ID		9699	115827
HPRD ID		09436	06704
Ensembl ID		ENSG00000176406	ENSG00000152932
Uniprot IDs		A0A8Q3SIU4 A0A8Q3SJ53 A0A994J503 A0A994J5M6 A0A994J7W6 F8W6W8 Q9UQ26	Q96E17
PDB IDs		1V27 1WFG	6Y7G
Enriched GO Terms of Interacting Partners?		Myosin V Binding Exocytosis Secretion By Cell Secretion Regulation Of Exocytosis Establishment Of Protein Localization Synaptic Vesicle Protein Transport GTP-dependent Protein Binding Endosome Positive Regulation Of Regulated Secretory Pathway Regulation Of Transport Vesicle-mediated Transport GTPase Activity Regulation Of Vesicle-mediated Transport Regulation Of Secretion By Cell Intracellular Protein Localization GTP Binding Regulation Of Secretion Positive Regulation Of Exocytosis Positive Regulation Of Transport Nucleotide Binding Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Regulation Of Regulated Secretory Pathway Positive Regulation Of Secretion By Cell Positive Regulation Of Secretion Plasma Membrane Membrane Peptide Secretion GDP Binding Presynapse Golgi Apparatus Regulation Of Synaptic Vesicle Cycle Peptide Transport Antigen Processing And Presentation Small GTPase Binding Regulation Of Biological Quality Secretory Granule Regulated Exocytosis Vesicle Organization Intracellular Vesicle Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Perinuclear Region Of Cytoplasm Amide Transport Signal Release Calcium-ion Regulated Exocytosis Regulation Of Vesicle Fusion Synaptic Vesicle Transport
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