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TRAF4 and QARS1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
TRAF4
QARS1
Description
TNF receptor associated factor 4
glutaminyl-tRNA synthetase 1
Image
GO Annotations
Cellular Component
Fibrillar Center
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Bicellular Tight Junction
Membrane
Perinuclear Region Of Cytoplasm
Anchoring Junction
Cytoplasm
Mitochondrial Matrix
Cytosol
Aminoacyl-tRNA Synthetase Multienzyme Complex
Protein-containing Complex
Molecular Function
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Transferase Activity
Enzyme Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Signaling Adaptor Activity
Identical Protein Binding
Metal Ion Binding
WW Domain Binding
Nucleotide Binding
Aminoacyl-tRNA Ligase Activity
Glutamine-tRNA Ligase Activity
Protein Kinase Inhibitor Activity
Protein Binding
ATP Binding
Ligase Activity
Protein Kinase Binding
Biological Process
Immune System Process
Apoptotic Process
Signal Transduction
Cell Surface Receptor Signaling Pathway
Respiratory Gaseous Exchange By Respiratory System
Respiratory Tube Development
Regulation Of Apoptotic Process
Regulation Of Canonical NF-kappaB Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Innate Immune Response
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Translation
TRNA Aminoacylation For Protein Translation
Glutaminyl-tRNA Aminoacylation
Brain Development
Negative Regulation Of Stress-activated MAPK Cascade
TRNA Aminoacylation
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
Mitochondrial tRNA aminoacylation
Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Diseases
GWAS
Interacting Genes
137 interacting genes:
ABI3
ACTMAP
ALKBH4
ANXA1
AR
ATOSB
ATOX1
BACH2
BAHD1
BANP
BCKDK
BCL6B
BEGAIN
BEX3
BYSL
CALCOCO2
CAV1
CBL
CBLC
CCHCR1
CENPE
CEP85
CHEK1
CHUK
DISC1
DNM2
DPEP2NB
DTX3
EXOC7
EYA2
EZHIP
FAM90A1
FAT1
FBXL18
FRS3
FTH1
GOLGA2
GOLGA6A
GOLGA6L9
GORASP1
GORASP2
GPRASP1
HEY2
HGS
HMG20A
HOMEZ
HOXA1
HOXB5
IRAK1
IRS1
ISYNA1
KANK2
KANSL1
KDM1A
KRT31
KRT36
LENG8
LNX1
LTBR
MAGEC2
MAGED1
MAP3K4
MRPL28
NCF1
NGFR
NHERF2
NOS1AP
NPAS2
NTRK1
NUDT16L1
OGT
PCSK5
PDE4DIP
PHLDA1
PICK1
PKD1P1
PLAGL2
PLEKHA7
PLSCR1
POLR2J
POLR2J3
PSMC3
QARS1
RAD54L2
RBPMS
REXO1L6P
RNF114
RNF144B
RNF4
RPS6KB1
SF3B4
SIGLEC7
SMURF1
SMURF2
SNRPB
SORBS2
SPDL1
SUMO1
TARBP2
TAX1BP1
TBC1D7
TBC1D8
TFAP4
TGFB1I1
TICAM1
TNFRSF4
TP53BP2
TRAF6
TRIM27
TRIM37
TSGA10IP
TYK2
UBC
UBE2D1
UBE2I
UBL4A
UBL4B
USP7
VPS52
WBP11
WWP1
WWP2
ZBTB16
ZBTB26
ZC3H12C
ZMYM5
ZNF177
ZNF275
ZNF3
ZNF512B
ZNF559-ZNF177
ZNF581
ZNF620
ZNF688
ZNF784
ZNF835
ZRANB1
158 interacting genes:
ACTN2
ANXA7
APP
ASL
B9D2
BIRC7
BTG3
CCDC33
CDK4
CDKN1A
CLTC
COG6
CPNE3
CTBP2
DISC1
DNM2
DPPA4
DTX2
DUSP11
EDC3
EFHC2
ESS2
FAM118B
FAM161A
FAM83A
GADD45A
GPBP1
GSK3B
GSTZ1
H2AX
HES7
HMG20A
HOXA1
IK
IKZF1
IRF1
KCNE3
KLC3
KRT36
LAMTOR3
LGALS9B
LGALS9C
LNX1
LZTS1
LZTS2
MAP3K5
MCCD1
MESD
MID2
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR155
MIR15A
MIR15B
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7G
MIRLET7I
NAB2
NEBL
NFKBID
NLGN3
NOXA1
PICK1
PIK3R3
PIN1
PRDM6
PRRC2A
PTPN21
RARS1
RBFOX2
REL
RNF10
RNF11
SAXO4
SF3B4
SHLD1
SLA
SMAD9
SMN1
SNCA
SORBS3
SP7
SPATC1L
SPDYE4
SPRED2
STK3
TADA2A
TCF12
TGM7
TK1
TLE5
TRAF2
TRAF4
TRIM27
TRIM35
TRIP13
TSC22D1
TTR
USHBP1
VPS37B
XIAP
ZMYND12
Entrez ID
9618
5859
HPRD ID
03915
07223
Ensembl ID
ENSG00000076604
ENSG00000172053
Uniprot IDs
Q9BUZ4
B7Z840
P47897
PDB IDs
2EOD
2YUC
3ZJB
4K8U
4M4E
5YC1
4R3Z
4YE6
4YE8
4YE9
Enriched GO Terms of Interacting Partners
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Protein Binding
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of Primary Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Protein Modification Process
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
Cytosol
Protein Modification By Small Protein Conjugation
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Protein Ubiquitination
Regulation Of Transcription By RNA Polymerase II
Ubiquitin-protein Transferase Activity
Regulation Of Gene Expression
Ubiquitin Protein Ligase Activity
Post-translational Protein Modification
Negative Regulation Of RNA Metabolic Process
Modification-dependent Protein Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Cell Surface Toll-like Receptor Signaling Pathway
Identical Protein Binding
Ubiquitin-dependent Protein Catabolic Process
Protein Metabolic Process
Cell Surface Pattern Recognition Receptor Signaling Pathway
Positive Regulation Of Macromolecule Metabolic Process
Proteolysis Involved In Protein Catabolic Process
Cytoplasm
Positive Regulation Of Metabolic Process
Regulation Of Protein Modification Process
Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Protein Ubiquitination
Regulation Of Post-translational Protein Modification
Regulation Of Protein Ubiquitination
PML Body
Regulation Of Programmed Cell Death
Negative Regulation Of Macromolecule Biosynthetic Process
Signaling Adaptor Activity
Zinc Ion Binding
Proteolysis
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Macromolecule Catabolic Process
Positive Regulation Of Protein Metabolic Process
RISC Complex
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Regulatory NcRNA-mediated Gene Silencing
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MiRNA-mediated Gene Silencing By Inhibition Of Translation
MRNA 3'-UTR Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Extracellular Vesicle
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Cytokine Production
MRNA Destabilization
RNA Destabilization
Negative Regulation Of Translation
Positive Regulation Of MRNA Catabolic Process
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Multicellular Organismal Process
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Regulation Of Metabolic Process
Positive Regulation Of MRNA Metabolic Process
Negative Regulation Of Cell Motility
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Cell Migration
Negative Regulation Of Locomotion
Regulation Of MRNA Stability
Negative Regulation Of Developmental Process
Regulation Of Angiogenesis
Regulation Of RNA Stability
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Vasculature Development
Negative Regulation Of Endothelial Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Protein Metabolic Process
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Translation
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Endothelial Cell Migration
Regulation Of Cytokine Production
Regulation Of Developmental Process
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