TRAF4 and BYSL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRAF4	BYSL
Gene Name		TNF receptor-associated factor 4	bystin-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Plasma Membrane Tight Junction Perinuclear Region Of Cytoplasm	Nucleus Nucleolus Cytoplasm Membrane Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	DNA Binding Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Thioesterase Binding WW Domain Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Apoptotic Process Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity Respiratory Gaseous Exchange Protein Ubiquitination Respiratory Tube Development Regulation Of Apoptotic Process Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Protein Homodimerization Activity	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Trophectodermal Cell Differentiation Cell Adhesion Female Pregnancy Cell Proliferation
Pathways
Drugs
Diseases
GWAS			Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Red blood cell count ( 20139978)
Protein-Protein Interactions		69 interactors: ALKBH4 ARNT2 BAHD1 BANP BCKDK BCL6B BYSL CALCOCO2 CBL CBLC CCHCR1 CENPE CHUK DTX3 EXOC7 FBXL18 FTH1 GORASP2 GPRASP1 HOMEZ IRAK1 ISYNA1 KANSL1 KDM1A KRT31 KRT40 LTBR MAGED1 MAP3K4 MRPL28 NCF1 NGFR NGFRAP1 NOS1AP NPAS2 PDE4DIP PKD1P1 PLSCR1 PSMC3 QARS REXO1L6P RNF114 RPS6KB1 SIGLEC7 SMURF1 SMURF2 SORBS2 SPDL1 SUMO1 TARBP2 TBC1D7 TBC1D8 TGFB1I1 TICAM1 TNFRSF4 TP53BP2 TRAF6 TRIM37 TYK2 UBE2I UBL4A UBL4B USP7 WBP11 WWP1 WWP2 ZNF3 ZNF512B ZNF581	65 interactors: AES AIMP2 APP BEND7 C1orf94 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 EMD EPS8 FAM9B FXR2 GMCL1 GOLGA2 HMBOX1 IKZF1 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LONRF1 LTV1 LZTS2 MID1 MID2 MIPOL1 MRFAP1L1 MTUS2 NECAB2 OLIG3 PDE4DIP PHC2 PNMA1 PNMA2 RALYL SMN2 SSX2IP STX11 TEKT1 THAP1 TNIP1 TRAF4 TRIM27 TRIM37 TRIM54 TRIP6 TRO TROAP UBE2H VPS37B ZBTB14 ZBTB8A ZFP64
Entrez ID		9618	705
HPRD ID		03915	04848
Ensembl ID		ENSG00000076604	ENSG00000112578
Uniprot IDs		Q9BUZ4	Q13895
PDB IDs		2EOD 2YUC 4M4E
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Gene Expression Regulation Of Signal Transduction Regulation Of Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nucleic Acid-templated Transcription Regulation Of Signaling Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Response To Growth Factor Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Signal Transduction Cellular Protein Modification Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Protein Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Innate Immune Response Negative Regulation Of Transcription, DNA-templated Response To Organic Substance Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Programmed Cell Death Proteolysis Involved In Cellular Protein Catabolic Process Response To Cytokine Cellular Protein Catabolic Process Cell Death Death Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Protein Catabolic Process	Gene Expression Protein Localization To Microtubule RNA Metabolic Process Regulation Of Protein Binding Transcription, DNA-templated Negative Regulation Of Cytoskeleton Organization RNA Biosynthetic Process Cell Adhesion Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Protein Complex Disassembly Negative Regulation Of Biosynthetic Process Dendritic Cell Migration Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Protein Modification By Small Protein Conjugation Regulation Of Viral Release From Host Cell Protein K11-linked Ubiquitination Regulation Of Protein Depolymerization Regulation Of Cellular Process Negative Regulation Of RNA Biosynthetic Process Organelle Organization Regulation Of Binding Regulation Of Metabolic Process Regulation Of Protein Complex Disassembly Cellular Macromolecule Biosynthetic Process Immune System Process Macromolecule Biosynthetic Process Negative Regulation Of Microtubule Depolymerization Cellular Component Assembly Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Neutrophil Differentiation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Memory T Cell Proliferation Regulation Of Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Mitotic Cell Cycle Regulation Of Microtubule Cytoskeleton Organization Developmental Process Microtubule-based Process Leukocyte Cell-cell Adhesion Negative Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		bcr cart cd40 cd54 cd95 ciap2 define dr3 driven effector engagement fas icam linking mapk mapkapk minimal p38 permeable perturbed potentiating requirement responsive sb203580 selectively stimulates tonsillar traf1 unaffected	c6ofr49 c6orf49 ccnd2 ccnd3 ccne1 cdk6 cdkn1a cdkn1b cdkn2a cdkn2b cdkn2c cdkn2d datasets disequilibrium frs3 genotyped heredity kip1 p15 p18 p19 p33 participating pgc rs2479717 tagging tags trfp usp49
Tagcloud (Difference) ?		bcr cart cd40 cd54 cd95 ciap2 define dr3 driven effector engagement fas icam linking mapk mapkapk minimal p38 permeable perturbed potentiating requirement responsive sb203580 selectively stimulates tonsillar traf1 unaffected	c6ofr49 c6orf49 ccnd2 ccnd3 ccne1 cdk6 cdkn1a cdkn1b cdkn2a cdkn2b cdkn2c cdkn2d datasets disequilibrium frs3 genotyped heredity kip1 p15 p18 p19 p33 participating pgc rs2479717 tagging tags trfp usp49
Tagcloud (Intersection) ?