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TRAF4 and TBC1D8
Number of citations of the paper that reports this interaction (PubMedID
12023963
)
0
Data Source:
HPRD
(two hybrid)
TRAF4
TBC1D8
Description
TNF receptor associated factor 4
TBC1 domain family member 8
Image
No pdb structure
GO Annotations
Cellular Component
Fibrillar Center
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Bicellular Tight Junction
Membrane
Perinuclear Region Of Cytoplasm
Anchoring Junction
Membrane
Molecular Function
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Transferase Activity
Enzyme Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Signaling Adaptor Activity
Identical Protein Binding
Metal Ion Binding
WW Domain Binding
GTPase Activator Activity
Protein Binding
Biological Process
Immune System Process
Apoptotic Process
Signal Transduction
Cell Surface Receptor Signaling Pathway
Respiratory Gaseous Exchange By Respiratory System
Respiratory Tube Development
Regulation Of Apoptotic Process
Regulation Of Canonical NF-kappaB Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Innate Immune Response
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
System Process
Blood Circulation
Positive Regulation Of Cell Population Proliferation
Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS
Alanine aminotransferase levels (
34315874
)
Aspartate aminotransferase levels (
34315874
)
Carotid intima media thickness x smoking interaction (
32117412
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Decline in glucose metabolism in posterior cingulate cortex (
29130521
)
Granulocyte count (
27863252
)
Heel bone mineral density x serum urate levels interaction (
34046847
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Intraocular pressure (
29785010
)
Lymphocyte percentage of white cells (
32888494
)
Myeloid white cell count (
27863252
)
Neutrophil count (
32888494
)
Neutrophil percentage of white cells (
32888494
)
Osteoporosis-related phenotypes (
20548944
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Sum neutrophil eosinophil counts (
27863252
)
White blood cell count (
32888494
)
Interacting Genes
137 interacting genes:
ABI3
ACTMAP
ALKBH4
ANXA1
AR
ATOSB
ATOX1
BACH2
BAHD1
BANP
BCKDK
BCL6B
BEGAIN
BEX3
BYSL
CALCOCO2
CAV1
CBL
CBLC
CCHCR1
CENPE
CEP85
CHEK1
CHUK
DISC1
DNM2
DPEP2NB
DTX3
EXOC7
EYA2
EZHIP
FAM90A1
FAT1
FBXL18
FRS3
FTH1
GOLGA2
GOLGA6A
GOLGA6L9
GORASP1
GORASP2
GPRASP1
HEY2
HGS
HMG20A
HOMEZ
HOXA1
HOXB5
IRAK1
IRS1
ISYNA1
KANK2
KANSL1
KDM1A
KRT31
KRT36
LENG8
LNX1
LTBR
MAGEC2
MAGED1
MAP3K4
MRPL28
NCF1
NGFR
NHERF2
NOS1AP
NPAS2
NTRK1
NUDT16L1
OGT
PCSK5
PDE4DIP
PHLDA1
PICK1
PKD1P1
PLAGL2
PLEKHA7
PLSCR1
POLR2J
POLR2J3
PSMC3
QARS1
RAD54L2
RBPMS
REXO1L6P
RNF114
RNF144B
RNF4
RPS6KB1
SF3B4
SIGLEC7
SMURF1
SMURF2
SNRPB
SORBS2
SPDL1
SUMO1
TARBP2
TAX1BP1
TBC1D7
TBC1D8
TFAP4
TGFB1I1
TICAM1
TNFRSF4
TP53BP2
TRAF6
TRIM27
TRIM37
TSGA10IP
TYK2
UBC
UBE2D1
UBE2I
UBL4A
UBL4B
USP7
VPS52
WBP11
WWP1
WWP2
ZBTB16
ZBTB26
ZC3H12C
ZMYM5
ZNF177
ZNF275
ZNF3
ZNF512B
ZNF559-ZNF177
ZNF581
ZNF620
ZNF688
ZNF784
ZNF835
ZRANB1
3 interacting genes:
SPP1
TRAF1
TRAF4
Entrez ID
9618
11138
HPRD ID
03915
06752
Ensembl ID
ENSG00000076604
ENSG00000204634
Uniprot IDs
Q9BUZ4
J3KQ40
O95759
PDB IDs
2EOD
2YUC
3ZJB
4K8U
4M4E
5YC1
Enriched GO Terms of Interacting Partners
?
Protein Binding
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of Primary Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Protein Modification Process
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
Cytosol
Protein Modification By Small Protein Conjugation
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Protein Ubiquitination
Regulation Of Transcription By RNA Polymerase II
Ubiquitin-protein Transferase Activity
Regulation Of Gene Expression
Ubiquitin Protein Ligase Activity
Post-translational Protein Modification
Negative Regulation Of RNA Metabolic Process
Modification-dependent Protein Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Cell Surface Toll-like Receptor Signaling Pathway
Identical Protein Binding
Ubiquitin-dependent Protein Catabolic Process
Protein Metabolic Process
Cell Surface Pattern Recognition Receptor Signaling Pathway
Positive Regulation Of Macromolecule Metabolic Process
Proteolysis Involved In Protein Catabolic Process
Cytoplasm
Positive Regulation Of Metabolic Process
Regulation Of Protein Modification Process
Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Protein Ubiquitination
Regulation Of Post-translational Protein Modification
Regulation Of Protein Ubiquitination
PML Body
Regulation Of Programmed Cell Death
Negative Regulation Of Macromolecule Biosynthetic Process
Signaling Adaptor Activity
Zinc Ion Binding
Proteolysis
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Macromolecule Catabolic Process
Positive Regulation Of Protein Metabolic Process
Thioesterase Binding
Tumor Necrosis Factor Receptor Binding
Signaling Adaptor Activity
Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Positive Regulation Of Estradiol Secretion
Regulation Of Estradiol Secretion
Androgen Catabolic Process
Ubiquitin Protein Ligase Binding
Regulation Of Canonical NF-kappaB Signal Transduction
Cellular Response To Testosterone Stimulus
Response To 2,3,7,8-tetrachlorodibenzodioxine
Positive Regulation Of Bone Resorption
Response To Macrophage Colony-stimulating Factor
Negative Regulation Of Collateral Sprouting
Negative Regulation Of Axon Regeneration
Negative Regulation Of Neuron Projection Regeneration
Respiratory Tube Development
Hormone Catabolic Process
Regulation Of Collateral Sprouting
Decidualization
Regulation Of Neuron Projection Regeneration
Perinuclear Region Of Cytoplasm
Response To Vitamin D
Regulation Of Axon Regeneration
Small Molecule Binding
Androgen Metabolic Process
Steroid Catabolic Process
Respiratory Gaseous Exchange By Respiratory System
WW Domain Binding
Extracellular Matrix Binding
Regulation Of Bone Resorption
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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