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TRAF4 and BEX3
Number of citations of the paper that reports this interaction (PubMedID
10514511
)
0
Data Source:
HPRD
(in vitro, in vivo)
TRAF4
BEX3
Description
TNF receptor associated factor 4
brain expressed X-linked 3
Image
No pdb structure
GO Annotations
Cellular Component
Fibrillar Center
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Bicellular Tight Junction
Membrane
Perinuclear Region Of Cytoplasm
Anchoring Junction
Nucleus
Cytoplasm
Cytosol
Molecular Function
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Transferase Activity
Enzyme Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Signaling Adaptor Activity
Identical Protein Binding
Metal Ion Binding
WW Domain Binding
Signaling Receptor Binding
Death Receptor Binding
Nerve Growth Factor Receptor Binding
Protein Binding
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Identical Protein Binding
Metal Ion Binding
Molecular Function Inhibitor Activity
Biological Process
Immune System Process
Apoptotic Process
Signal Transduction
Cell Surface Receptor Signaling Pathway
Respiratory Gaseous Exchange By Respiratory System
Respiratory Tube Development
Regulation Of Apoptotic Process
Regulation Of Canonical NF-kappaB Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Innate Immune Response
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Apoptotic Process
Signal Transduction
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Protein Ubiquitination
Pathways
NADE modulates death signalling
Drugs
Diseases
GWAS
Interacting Genes
137 interacting genes:
ABI3
ACTMAP
ALKBH4
ANXA1
AR
ATOSB
ATOX1
BACH2
BAHD1
BANP
BCKDK
BCL6B
BEGAIN
BEX3
BYSL
CALCOCO2
CAV1
CBL
CBLC
CCHCR1
CENPE
CEP85
CHEK1
CHUK
DISC1
DNM2
DPEP2NB
DTX3
EXOC7
EYA2
EZHIP
FAM90A1
FAT1
FBXL18
FRS3
FTH1
GOLGA2
GOLGA6A
GOLGA6L9
GORASP1
GORASP2
GPRASP1
HEY2
HGS
HMG20A
HOMEZ
HOXA1
HOXB5
IRAK1
IRS1
ISYNA1
KANK2
KANSL1
KDM1A
KRT31
KRT36
LENG8
LNX1
LTBR
MAGEC2
MAGED1
MAP3K4
MRPL28
NCF1
NGFR
NHERF2
NOS1AP
NPAS2
NTRK1
NUDT16L1
OGT
PCSK5
PDE4DIP
PHLDA1
PICK1
PKD1P1
PLAGL2
PLEKHA7
PLSCR1
POLR2J
POLR2J3
PSMC3
QARS1
RAD54L2
RBPMS
REXO1L6P
RNF114
RNF144B
RNF4
RPS6KB1
SF3B4
SIGLEC7
SMURF1
SMURF2
SNRPB
SORBS2
SPDL1
SUMO1
TARBP2
TAX1BP1
TBC1D7
TBC1D8
TFAP4
TGFB1I1
TICAM1
TNFRSF4
TP53BP2
TRAF6
TRIM27
TRIM37
TSGA10IP
TYK2
UBC
UBE2D1
UBE2I
UBL4A
UBL4B
USP7
VPS52
WBP11
WWP1
WWP2
ZBTB16
ZBTB26
ZC3H12C
ZMYM5
ZNF177
ZNF275
ZNF3
ZNF512B
ZNF559-ZNF177
ZNF581
ZNF620
ZNF688
ZNF784
ZNF835
ZRANB1
43 interacting genes:
AIMP2
BFSP2
CACYBP
CBY2
CCDC116
CCDC85B
CTNNBL1
DIABLO
DSCR9
EMILIN1
ENKD1
FSD2
FTCD
GOLGA8EP
GOLGA8F
ING4
ING5
KRT34
MCCD1
MDFI
MIF
MNAT1
NECAB2
NGFR
NTRK3
PTPN13
S100A1
S100Z
SIVA1
SMARCD1
SMPD1
TACC3
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
TSNAX
USHBP1
VTA1
YWHAE
ZNF417
Entrez ID
9618
27018
HPRD ID
03915
02291
Ensembl ID
ENSG00000076604
ENSG00000166681
Uniprot IDs
Q9BUZ4
Q00994
PDB IDs
2EOD
2YUC
3ZJB
4K8U
4M4E
5YC1
Enriched GO Terms of Interacting Partners
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Protein Binding
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of Primary Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Protein Modification Process
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
Cytosol
Protein Modification By Small Protein Conjugation
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Protein Ubiquitination
Regulation Of Transcription By RNA Polymerase II
Ubiquitin-protein Transferase Activity
Regulation Of Gene Expression
Ubiquitin Protein Ligase Activity
Post-translational Protein Modification
Negative Regulation Of RNA Metabolic Process
Modification-dependent Protein Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Cell Surface Toll-like Receptor Signaling Pathway
Identical Protein Binding
Ubiquitin-dependent Protein Catabolic Process
Protein Metabolic Process
Cell Surface Pattern Recognition Receptor Signaling Pathway
Positive Regulation Of Macromolecule Metabolic Process
Proteolysis Involved In Protein Catabolic Process
Cytoplasm
Positive Regulation Of Metabolic Process
Regulation Of Protein Modification Process
Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Protein Ubiquitination
Regulation Of Post-translational Protein Modification
Regulation Of Protein Ubiquitination
PML Body
Regulation Of Programmed Cell Death
Negative Regulation Of Macromolecule Biosynthetic Process
Signaling Adaptor Activity
Zinc Ion Binding
Proteolysis
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Macromolecule Catabolic Process
Positive Regulation Of Protein Metabolic Process
Tumor Necrosis Factor Receptor Binding
Thioesterase Binding
CD40 Receptor Complex
Signaling Adaptor Activity
Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Apoptotic Process
Ubiquitin Protein Ligase Binding
Positive Regulation Of Programmed Cell Death
CD40 Signaling Pathway
Interleukin-17-mediated Signaling Pathway
Cytoplasmic Side Of Plasma Membrane
Regulation Of Intracellular Signal Transduction
Regulation Of Canonical NF-kappaB Signal Transduction
A2A Adenosine Receptor Binding
DNA Replication-dependent Chromatin Disassembly
Regulation Of MAPK Cascade
Neurotrophin Binding
Positive Regulation Of NF-kappaB Transcription Factor Activity
Apoptotic Process
Identical Protein Binding
Cell Death
Programmed Cell Death
Regulation Of DNA-binding Transcription Factor Activity
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of DNA-binding Transcription Factor Activity
Cell Surface Toll-like Receptor Signaling Pathway
Regulation Of Signal Transduction
Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Cell Surface Pattern Recognition Receptor Signaling Pathway
Positive Regulation Of JUN Kinase Activity
Regulation Of JNK Cascade
Negative Regulation Of Macrophage Migration
S100 Protein Binding
MyD88-independent Toll-like Receptor Signaling Pathway
Cytoplasm
Zinc Ion Binding
Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of MAPK Cascade
Regulation Of Cell Communication
Regulation Of Signaling
Apoptotic Signaling Pathway
Positive Regulation Of Cytokine Production Involved In Immune Response
Histone H3K4me3 Reader Activity
Regulation Of Macromolecule Metabolic Process
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Tagcloud (Intersection)
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