ITM2B and SYNE4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ITM2B	SYNE4
Gene Name		integral membrane protein 2B	spectrin repeat containing, nuclear envelope family member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Endosome Membrane Membrane Golgi-associated Vesicle Membrane Integral Component Of Organelle Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Integral Component Of Nuclear Outer Membrane LINC Complex
	Molecular Function	Beta-amyloid Binding Protein Binding ATP Binding
	Biological Process	Nervous System Development Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways		Amyloids
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP BCL2 CCDC155 NAALADL2 SYNE4	52 interactors: ABT1 ADIPOQ BRICD5 C10orf35 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FATE1 GADD45A GSK3B ITM2B KLC4 KLHL12 KLRG1 KTN1 MALL MARCH2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250
Entrez ID		9445	163183
HPRD ID		04878	08776
Ensembl ID		ENSG00000136156	ENSG00000181392
Uniprot IDs		Q5W0A3 Q9Y287	Q8N205
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Calcium Ion Homeostasis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neuron Apoptotic Process Neuron Death Oogenesis Regulation Of Multicellular Organism Growth Female Gamete Generation Sexual Reproduction Negative Regulation Of Cellular PH Reduction CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Retinal Cell Programmed Cell Death Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of Protein Binding Cell Growth Synaptic Growth At Neuromuscular Junction Reproduction Intracellular Receptor Signaling Pathway Cell Differentiation Regulation Of Retinal Cell Programmed Cell Death Collateral Sprouting In Absence Of Injury Positive Regulation Of Neuron Maturation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Cochlear Nucleus Development Regulation Of Nitrogen Utilization Germ Cell Development Reproductive Process Regulation Of Binding Establishment Of Epithelial Cell Apical/basal Polarity Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Mitochondrial Depolarization Developmental Growth Regulation Of Developmental Growth Cellular Calcium Ion Homeostasis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Neuron Maturation Negative Regulation Of Cell Development Response To Light Stimulus Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Negative Regulation Of Calcium Ion Transport Into Cytosol Neuron Remodeling Regulation Of Cellular Amino Acid Metabolic Process B Cell Lineage Commitment Establishment Of Monopolar Cell Polarity Regulation Of Protein Heterodimerization Activity	ER To Golgi Vesicle-mediated Transport Negative Regulation Of Binding Regulation Of Binding Golgi Vesicle Transport Adiponectin-activated Signaling Pathway Vesicle Fusion With Golgi Apparatus Negative Regulation Of Protein Binding Response To External Stimulus Regulation Of Glycogen (starch) Synthase Activity Cellular Response To Mechanical Stimulus Vesicle-mediated Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Intracellular Signal Transduction
Tagcloud ?		app bace1 bri2 complexin constituted dementias exocytosis grasp interactome munc nsf psens recycling secretases sensors snap25 snap47 snaps snare snares synaptic synaptotagmin syntaxin undergoes underline vamp1 vamp2 vesicles vesicular
Tagcloud (Difference) ?		app bace1 bri2 complexin constituted dementias exocytosis grasp interactome munc nsf psens recycling secretases sensors snap25 snap47 snaps snare snares synaptic synaptotagmin syntaxin undergoes underline vamp1 vamp2 vesicles vesicular
Tagcloud (Intersection) ?