ITM2B and CCDC155

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ITM2B	CCDC155
Gene Name		integral membrane protein 2B	coiled-coil domain containing 155
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Endosome Membrane Membrane Golgi-associated Vesicle Membrane Integral Component Of Organelle Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Chromosome, Telomeric Region Lateral Element Nuclear Outer Membrane Integral Component Of Membrane
	Molecular Function	Beta-amyloid Binding Protein Binding ATP Binding	Identical Protein Binding Dynein Complex Binding
	Biological Process	Nervous System Development Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Double-strand Break Repair Via Homologous Recombination Spermatogenesis Oogenesis Chromosome Localization To Nuclear Envelope Involved In Synapsis
Pathways		Amyloids
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP BCL2 CCDC155 NAALADL2 SYNE4	70 interactors: ABHD1 ADIPOQ ATF7 BAG5 BCL2L2 BET1 C17orf62 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CRABP2 CXCL16 CXCL9 FAM161A FAM90A1 FATE1 FIS1 FRA10AC1 FTCD GABARAPL2 GALNT2 GOSR2 GPATCH4 GPR25 HMOX1 ITM2B JAGN1 KDM1A LARP1 LENG1 LHFPL5 MALL MARCH2 MFSD5 MMP14 MS4A1 MTX2 NRIP3 NSG1 OLFM4 PDGFRA PLP2 PPP1R18 RIPPLY2 RNF146 RSRC2 RTP2 SENP2 SERP2 SGTA SLC30A2 SLC41A2 SLN SMCO4 STBD1 STX5 TCF25 TMEM14C TMEM199 TMEM41A TMPRSS4 TRAF3IP3 TSHZ3 UPK1B UPK2 VAMP1 VAMP4 ZNF250
Entrez ID		9445	147872
HPRD ID		04878	08134
Ensembl ID		ENSG00000136156	ENSG00000161609
Uniprot IDs		Q5W0A3 Q9Y287	Q8N6L0
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Calcium Ion Homeostasis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neuron Apoptotic Process Neuron Death Oogenesis Regulation Of Multicellular Organism Growth Female Gamete Generation Sexual Reproduction Negative Regulation Of Cellular PH Reduction CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Retinal Cell Programmed Cell Death Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of Protein Binding Cell Growth Synaptic Growth At Neuromuscular Junction Reproduction Intracellular Receptor Signaling Pathway Cell Differentiation Regulation Of Retinal Cell Programmed Cell Death Collateral Sprouting In Absence Of Injury Positive Regulation Of Neuron Maturation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Cochlear Nucleus Development Regulation Of Nitrogen Utilization Germ Cell Development Reproductive Process Regulation Of Binding Establishment Of Epithelial Cell Apical/basal Polarity Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Mitochondrial Depolarization Developmental Growth Regulation Of Developmental Growth Cellular Calcium Ion Homeostasis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Neuron Maturation Negative Regulation Of Cell Development Response To Light Stimulus Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Negative Regulation Of Calcium Ion Transport Into Cytosol Neuron Remodeling Regulation Of Cellular Amino Acid Metabolic Process B Cell Lineage Commitment Establishment Of Monopolar Cell Polarity Regulation Of Protein Heterodimerization Activity	Membrane Fusion Organelle Fusion Vesicle Fusion Vesicle Fusion With Golgi Apparatus Negative Regulation Of Binding Membrane Organization Vesicle Organization Organelle Disassembly T Cell Chemotaxis SNARE Complex Assembly Negative Regulation Of Protein Binding Regulation Of Binding Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Intracellular Signal Transduction Regulation Of Intrinsic Apoptotic Signaling Pathway Vesicle-mediated Transport Regulation Of Cellular Component Organization Lymphocyte Chemotaxis Granulocyte Differentiation Endothelial Cell Proliferation T Cell Migration Transport Epithelial Cell Proliferation Low-density Lipoprotein Particle Clearance Embryo Development Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway ER To Golgi Vesicle-mediated Transport Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Metanephros Development Mitochondrion Degradation Lymphocyte Migration Establishment Of Protein Localization Response To Linoleic Acid Positive Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Renal Albumin Absorption Negative Regulation Of Metanephric Mesenchymal Cell Migration Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Positive Regulation Of Metanephric Glomerular Visceral Epithelial Cell Development Detection Of Oxidative Stress Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Regulation Of Primitive Erythrocyte Differentiation Granulocyte Colony-stimulating Factor Signaling Pathway Molybdate Ion Transport
Tagcloud ?		app bace1 bri2 complexin constituted dementias exocytosis grasp interactome munc nsf psens recycling secretases sensors snap25 snap47 snaps snare snares synaptic synaptotagmin syntaxin undergoes underline vamp1 vamp2 vesicles vesicular
Tagcloud (Difference) ?		app bace1 bri2 complexin constituted dementias exocytosis grasp interactome munc nsf psens recycling secretases sensors snap25 snap47 snaps snare snares synaptic synaptotagmin syntaxin undergoes underline vamp1 vamp2 vesicles vesicular
Tagcloud (Intersection) ?