ITM2B and NAALADL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ITM2B	NAALADL2
Gene Name		integral membrane protein 2B	N-acetylated alpha-linked acidic dipeptidase-like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Endosome Membrane Membrane Golgi-associated Vesicle Membrane Integral Component Of Organelle Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Integral Component Of Membrane
	Molecular Function	Beta-amyloid Binding Protein Binding ATP Binding
	Biological Process	Nervous System Development Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Amyloids
Drugs
Diseases
GWAS			Height ( 23456168) Kawasaki disease ( 19132087) Metabolite levels (MHPG) ( 23319000) Sleep duration ( 23728906) Systemic lupus erythematosus ( 21408207)
Protein-Protein Interactions		5 interactors: APP BCL2 CCDC155 NAALADL2 SYNE4	6 interactors: APP GPR25 GRM2 ITM2B LAPTM4B SLC30A3
Entrez ID		9445	254827
HPRD ID		04878	16388
Ensembl ID		ENSG00000136156	ENSG00000177694
Uniprot IDs		Q5W0A3 Q9Y287	Q58DX5
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Calcium Ion Homeostasis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neuron Apoptotic Process Neuron Death Oogenesis Regulation Of Multicellular Organism Growth Female Gamete Generation Sexual Reproduction Negative Regulation Of Cellular PH Reduction CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Retinal Cell Programmed Cell Death Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of Protein Binding Cell Growth Synaptic Growth At Neuromuscular Junction Reproduction Intracellular Receptor Signaling Pathway Cell Differentiation Regulation Of Retinal Cell Programmed Cell Death Collateral Sprouting In Absence Of Injury Positive Regulation Of Neuron Maturation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Cochlear Nucleus Development Regulation Of Nitrogen Utilization Germ Cell Development Reproductive Process Regulation Of Binding Establishment Of Epithelial Cell Apical/basal Polarity Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Mitochondrial Depolarization Developmental Growth Regulation Of Developmental Growth Cellular Calcium Ion Homeostasis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Neuron Maturation Negative Regulation Of Cell Development Response To Light Stimulus Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Negative Regulation Of Calcium Ion Transport Into Cytosol Neuron Remodeling Regulation Of Cellular Amino Acid Metabolic Process B Cell Lineage Commitment Establishment Of Monopolar Cell Polarity Regulation Of Protein Heterodimerization Activity See more	Glutamate Receptor Signaling Pathway
Tagcloud ?		app bace1 bri2 complexin constituted dementias exocytosis grasp interactome munc nsf psens recycling secretases sensors snap25 snap47 snaps snare snares synaptic synaptotagmin syntaxin undergoes underline vamp1 vamp2 vesicles vesicular
Tagcloud (Difference) ?		app bace1 bri2 complexin constituted dementias exocytosis grasp interactome munc nsf psens recycling secretases sensors snap25 snap47 snaps snare snares synaptic synaptotagmin syntaxin undergoes underline vamp1 vamp2 vesicles vesicular
Tagcloud (Intersection) ?