SYNE4 and CSGALNACT2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SYNE4	CSGALNACT2
Gene Name		spectrin repeat containing, nuclear envelope family member 4	chondroitin sulfate N-acetylgalactosaminyltransferase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane LINC Complex	Golgi Membrane Membrane Integral Component Of Golgi Membrane Golgi Cisterna Membrane
	Molecular Function		Acetylgalactosaminyltransferase Activity Metal Ion Binding Glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Carbohydrate Metabolic Process Pathogenesis Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Chondroitin Sulfate Biosynthetic Process Small Molecule Metabolic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process
Pathways			MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective CHST14 causes EDS, musculocontractural type Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Defective CHST6 causes MCDC1 Glycogen storage diseases MPS IIID - Sanfilippo syndrome D Chondroitin sulfate biosynthesis MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A Defective CHSY1 causes TPBS MPS IV - Morquio syndrome B MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-Protein Interactions		52 interactors: ABT1 ADIPOQ BRICD5 C10orf35 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FATE1 GADD45A GSK3B ITM2B KLC4 KLHL12 KLRG1 KTN1 MALL MARCH2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250	1 interactors: SYNE4
Entrez ID		163183	55454
HPRD ID		08776	11348
Ensembl ID		ENSG00000181392	ENSG00000169826
Uniprot IDs		Q8N205	Q8N6G5
PDB IDs
Enriched GO Terms of Interacting Partners?		ER To Golgi Vesicle-mediated Transport Negative Regulation Of Binding Regulation Of Binding Golgi Vesicle Transport Adiponectin-activated Signaling Pathway Vesicle Fusion With Golgi Apparatus Negative Regulation Of Protein Binding Response To External Stimulus Regulation Of Glycogen (starch) Synthase Activity Cellular Response To Mechanical Stimulus Vesicle-mediated Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Intracellular Signal Transduction	Establishment Of Epithelial Cell Apical/basal Polarity Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Establishment Of Monopolar Cell Polarity Establishment Of Epithelial Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Morphogenesis Of A Polarized Epithelium Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Of Cell Polarity Establishment Or Maintenance Of Cell Polarity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis
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