LATS1 and MOB3C

Number of citations of the paper that reports this interaction (PMID 19739119)
11

Data Source:
BioGRID (pull down)

		LATS1	MOB3C
Gene Name		large tumor suppressor kinase 1	MOB kinase activator 3C
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Microtubule Organizing Center Cytosol
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding	Metal Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Sister Chromatid Segregation Protein Phosphorylation Mitotic Nuclear Division Hormone-mediated Signaling Pathway Keratinocyte Differentiation Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Hippo Signaling Regulation Of Protein Complex Assembly Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cytoplasmic Sequestering Of Protein Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: ALPP AMOT APP AURKB CAV1 CDK1 CEP76 EIF4EBP1 FOXL2 FSD2 GOLGA2 ITCH KRT31 LDOC1 LIMK1 MAGI3 MOAP1 MOB3A MOB3B MOB3C MOB4 NEDD4 NUAK1 NUAK2 PABPN1 PPP1R11 PPP6R3 PTEN RAC1 SMURF1 SMURF2 SPERT SSX2IP STK3 STK4 TAZ TFIP11 TRAF1 WWOX WWP1 WWTR1 YAP1 ZYX	12 interactors: APP CMTM3 FAM118A KRT40 LATS1 LATS2 NT5C2 SIAH1 TDO2 TFCP2 TNIP1 ZBTB10
Entrez ID		9113	148932
HPRD ID		09147	17584
Ensembl ID		ENSG00000131023	ENSG00000142961
Uniprot IDs		O95835	Q70IA8
PDB IDs
Enriched GO Terms of Interacting Partners?		Hippo Signaling Regulation Of Signal Transduction Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Signaling Intracellular Signal Transduction Regulation Of Wnt Signaling Pathway Regulation Of Apoptotic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Death Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Metabolic Process Regulation Of Protein Binding Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Signaling Tissue Development Cellular Protein Catabolic Process Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Cellular Response To Growth Factor Stimulus Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Anatomical Structure Morphogenesis Regulation Of Kinase Activity Signal Transduction Response To Growth Factor Cell Communication Positive Regulation Of Signal Transduction Regulation Of Developmental Growth Protein Catabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Protein Metabolic Process Response To Transforming Growth Factor Beta Cellular Macromolecule Catabolic Process Regulation Of Cell Development Negative Regulation Of Wnt Signaling Pathway Regulation Of Organ Growth Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Protein Kinase Activity Negative Regulation Of Cellular Metabolic Process	Hippo Signaling Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Neuron Apoptotic Process Neuron Death Regulation Of Signal Transduction Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Negative Regulation Of Phosphorylation Regulation Of Signaling Keratinocyte Differentiation Synaptic Growth At Neuromuscular Junction Tryptophan Catabolic Process To Acetyl-CoA Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Collateral Sprouting In Absence Of Injury Regulation Of Phosphorylation Negative Regulation Of Protein Serine/threonine Kinase Activity Epidermal Cell Differentiation Hormone-mediated Signaling Pathway Chemotaxis Negative Regulation Of Canonical Wnt Signaling Pathway Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Phosphorus Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Cellular Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of Protein Kinase Activity Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Neuron Remodeling Tryptophan Catabolic Process To Kynurenine Skin Development Negative Regulation Of Kinase Activity Kynurenine Metabolic Process Negative Regulation Of Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Epidermis Development Phosphorylation Regulation Of Cell Cycle Regulation Of B Cell Receptor Signaling Pathway Regulation Of Developmental Growth Adenosine Metabolic Process Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Tryptophan Catabolic Process
Tagcloud ?		accompanying carcinogenic cdc2 conservation corpus flies homologue hyperplastic hypogonadism hypogonadotropic infertility insufficiency lethality lh luteum mammalian melanogaster mosaic pituitary ref reminiscent reproductive rescues retardation sarcomas screens tumorigenesis tumours
Tagcloud (Difference) ?		accompanying carcinogenic cdc2 conservation corpus flies homologue hyperplastic hypogonadism hypogonadotropic infertility insufficiency lethality lh luteum mammalian melanogaster mosaic pituitary ref reminiscent reproductive rescues retardation sarcomas screens tumorigenesis tumours
Tagcloud (Intersection) ?