MOB3C and NT5C2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MOB3C	NT5C2
Gene Name		MOB kinase activator 3C	5-nucleotidase, cytosolic II
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytosol
	Molecular Function	Metal Ion Binding	Nucleotide Binding Protein Binding 5'-nucleotidase Activity Metal Ion Binding Nucleoside Phosphotransferase Activity
	Biological Process		Purine Nucleobase Metabolic Process Purine Nucleotide Catabolic Process Phosphorylation Dephosphorylation Drug Metabolic Process Small Molecule Metabolic Process IMP Metabolic Process Adenosine Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways			Purine catabolism Purine metabolism Metabolism of nucleotides Abacavir transport and metabolism Abacavir metabolism
Drugs			Adenosine triphosphate Ribavirin
Diseases
GWAS			Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blood pressure ( 21572416 21909110) Coronary heart disease ( 21378990) Schizophrenia ( 21926974 22688191 23894747) Systolic blood pressure ( 19430483 21909115)
Protein-Protein Interactions		12 interactors: APP CMTM3 FAM118A KRT40 LATS1 LATS2 NT5C2 SIAH1 TDO2 TFCP2 TNIP1 ZBTB10	10 interactors: ATP5O CALM1 FXR2 MOB1B MOB3B MOB3C NME7 NOC4L NUDT18 SDCBP
Entrez ID		148932	22978
HPRD ID		17584	02686
Ensembl ID		ENSG00000142961	ENSG00000076685
Uniprot IDs		Q70IA8	A8K6K2 B7Z382 P49902
PDB IDs			2J2C 2JC9 2JCM 2XCV 2XCW 2XCX 2XJB 2XJC 2XJD 2XJE 2XJF 4H4B
Enriched GO Terms of Interacting Partners?		Hippo Signaling Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Neuron Apoptotic Process Neuron Death Regulation Of Signal Transduction Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Negative Regulation Of Phosphorylation Regulation Of Signaling Keratinocyte Differentiation Synaptic Growth At Neuromuscular Junction Tryptophan Catabolic Process To Acetyl-CoA Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Collateral Sprouting In Absence Of Injury Regulation Of Phosphorylation Negative Regulation Of Protein Serine/threonine Kinase Activity Epidermal Cell Differentiation Hormone-mediated Signaling Pathway Chemotaxis Negative Regulation Of Canonical Wnt Signaling Pathway Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Phosphorus Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Cellular Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of Protein Kinase Activity Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Neuron Remodeling Tryptophan Catabolic Process To Kynurenine Skin Development Negative Regulation Of Kinase Activity Kynurenine Metabolic Process Negative Regulation Of Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Epidermis Development Phosphorylation Regulation Of Cell Cycle Regulation Of B Cell Receptor Signaling Pathway Regulation Of Developmental Growth Adenosine Metabolic Process Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Tryptophan Catabolic Process	Purine Nucleoside Metabolic Process Ribonucleotide Metabolic Process Nucleoside Metabolic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Nucleoside Diphosphate Metabolic Process Organophosphate Metabolic Process Nucleoside Triphosphate Biosynthetic Process GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Phosphate-containing Compound Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Regulation Of High Voltage-gated Calcium Channel Activity Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Regulation Of Extracellular Vesicular Exosome Assembly Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Membrane Organization Positive Regulation Of Phosphorylation Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Ribonucleoside Diphosphate Catabolic Process Establishment Of Localization In Cell Nucleoside Diphosphate Catabolic Process Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Deoxyribonucleoside Diphosphate Metabolic Process Detection Of Calcium Ion Substrate-dependent Cell Migration, Cell Extension Energy Derivation By Oxidation Of Organic Compounds Nucleotide Biosynthetic Process Purine Ribonucleoside Catabolic Process Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Small Molecule Metabolic Process Cellular Localization Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Tagcloud ?			atp2b1 atxn2 bdkrb2 cacnb2 csk cyp171a cyp17a1 cyp1a2 eh gwas hfe jan meant mthfr nppa nppb overlapped pharmacogenomics plcd3 plekha7 sh2b3 stk39 tbx3 tbx5 ulk3 ulk4 umod wnk4 znf652
Tagcloud (Difference) ?			atp2b1 atxn2 bdkrb2 cacnb2 csk cyp171a cyp17a1 cyp1a2 eh gwas hfe jan meant mthfr nppa nppb overlapped pharmacogenomics plcd3 plekha7 sh2b3 stk39 tbx3 tbx5 ulk3 ulk4 umod wnk4 znf652
Tagcloud (Intersection) ?