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MOB3C and TDO2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
MOB3C
TDO2
Gene Name
MOB kinase activator 3C
tryptophan 2,3-dioxygenase
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Molecular Function
Metal Ion Binding
Tryptophan 2,3-dioxygenase Activity
Amino Acid Binding
Oxygen Binding
Heme Binding
Metal Ion Binding
Biological Process
Tryptophan Catabolic Process
Tryptophan Catabolic Process To Kynurenine
Tryptophan Catabolic Process To Acetyl-CoA
Cellular Nitrogen Compound Metabolic Process
Small Molecule Metabolic Process
Oxidation-reduction Process
Pathways
Tryptophan catabolism
Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Speech perception in dyslexia (
19786962
)
Protein-Protein Interactions
12 interactors:
APP
CMTM3
FAM118A
KRT40
LATS1
LATS2
NT5C2
SIAH1
TDO2
TFCP2
TNIP1
ZBTB10
15 interactors:
ASMTL
DPM1
EIF4E
KDM1A
MEOX2
MOB1A
MOB3C
NGB
NMNAT1
PRMT6
PSMA1
REL
SDCBP
SDCBP2
ZFYVE26
Entrez ID
148932
6999
HPRD ID
17584
01847
Ensembl ID
ENSG00000142961
ENSG00000151790
Uniprot IDs
Q70IA8
P48775
PDB IDs
Enriched GO Terms of Interacting Partners
?
Hippo Signaling
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Neuron Apoptotic Process
Neuron Death
Regulation Of Signal Transduction
Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Negative Regulation Of Phosphorylation
Regulation Of Signaling
Keratinocyte Differentiation
Synaptic Growth At Neuromuscular Junction
Tryptophan Catabolic Process To Acetyl-CoA
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Collateral Sprouting In Absence Of Injury
Regulation Of Phosphorylation
Negative Regulation Of Protein Serine/threonine Kinase Activity
Epidermal Cell Differentiation
Hormone-mediated Signaling Pathway
Chemotaxis
Negative Regulation Of Canonical Wnt Signaling Pathway
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of Phosphorus Metabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Positive Regulation Of B Cell Receptor Signaling Pathway
Negative Regulation Of Wnt Signaling Pathway
Cellular Metabolic Process
Regulation Of Protein Kinase Activity
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Cellular Protein Metabolic Process
Neuron Remodeling
Tryptophan Catabolic Process To Kynurenine
Skin Development
Negative Regulation Of Kinase Activity
Kynurenine Metabolic Process
Negative Regulation Of Protein Metabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Epidermis Development
Phosphorylation
Regulation Of Cell Cycle
Regulation Of B Cell Receptor Signaling Pathway
Regulation Of Developmental Growth
Adenosine Metabolic Process
Negative Regulation Of Transferase Activity
Regulation Of Wnt Signaling Pathway
Tryptophan Catabolic Process
Tagcloud
?
agt
ass1
beadchip
benjamini
crym
differentiates
egr2
folr3
gja1
hochberg
hrasls
humanref
illumina
leiomyosarcoma
lms
lmss
masp1
nlgn1
nlgn4x
ostn
rorb
shmt1
slitrk4
thbs1
tnnt1
tspan10
tspan7
uterine
xrn2
Tagcloud (Difference)
?
agt
ass1
beadchip
benjamini
crym
differentiates
egr2
folr3
gja1
hochberg
hrasls
humanref
illumina
leiomyosarcoma
lms
lmss
masp1
nlgn1
nlgn4x
ostn
rorb
shmt1
slitrk4
thbs1
tnnt1
tspan10
tspan7
uterine
xrn2
Tagcloud (Intersection)
?