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MOB3C and KANK2
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
MOB3C
KANK2
Description
MOB kinase activator 3C
KN motif and ankyrin repeat domains 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytoplasm
Mitochondrion
Molecular Function
Protein Binding
Protein Kinase Activator Activity
Metal Ion Binding
Protein Binding
Biological Process
Signal Transduction
Negative Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Actin Filament Polymerization
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Regulation Of Rho Protein Signal Transduction
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Vitamin D Receptor Signaling Pathway
Kidney Epithelium Development
Podocyte Cell Migration
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS
Chronic kidney disease (
30226566
)
Hypertension (
30226566
)
Apolipoprotein B levels (
32203549
)
Cholesterol, total (
26780889
)
Coronary artery disease (
29212778
)
HDL cholesterol (
23505323
)
High light scatter reticulocyte count (
27863252
32888494
)
High light scatter reticulocyte percentage of red cells (
27863252
32888494
)
Immature fraction of reticulocytes (
27863252
32888494
)
Intraocular pressure (
31959993
)
Low density lipoprotein cholesterol levels (
32154731
32902719
)
Mean spheric corpuscular volume (
32888494
)
Non-HDL cholesterol levels (
32902719
)
Red cell distribution width (
28957414
32888494
27863252
)
Reticulocyte count (
27863252
32888494
)
Reticulocyte fraction of red cells (
27863252
32888494
)
Triglyceride levels (
32203549
)
Interacting Genes
18 interacting genes:
APP
CMTM3
FAM118A
FBXO7
IKZF4
KANK2
KRT40
LATS1
LATS2
NT5C2
PCYT1A
PICK1
PTPN21
SIAH1
TDO2
TFCP2
TNIP1
ZBTB10
187 interacting genes:
ABI3
AEN
ANKRD11
AP2B1
ARL14EP
ASB15
BEND7
BIRC7
BLZF1
BORCS6
C2orf68
CADPS
CAMK2G
CAPN3
CARD10
CARD9
CBX8
CCDC33
CCDC57
CCDC88B
CDC20B
CDC5L
CDKL3
CEACAM6
CEP55
CEP63
CEP70
CFAP68
CHCHD3
CHIC2
CINP
COG6
CRX
CSNK2A1
CUTC
CWF19L2
CYTH4
DDIT4L
DLGAP3
DPEP2NB
DTX2
DYNLL1
EFHC2
EIF4E
ELOA
EXOSC8
FAM161A
FAM90A1
FHL2
FHL3
FKBP6
GADD45GIP1
GATA1
GEMIN4
GKAP1
GMCL1
GMNN
GOLGA2
GOLGA6A
GOLGA6L9
GPANK1
GPKOW
GPSM1
GRB10
HAND2
HOMER3
HSF2BP
HSPB2
HSPB2-C11orf52
IHO1
IKZF3
IL16
KIF9
KIFAP3
KIFC3
KRT27
KRT31
KRT34
KRT40
KRT75
KRT86
KRTAP6-3
L3MBTL3
LBX1
LENG1
LHX1
LHX3
LMO1
LMO2
LMO3
LMO4
LZTS1
MAGEB4
MCCD1
MCRS1
MED19
MEOX1
MEOX2
MID2
MITD1
MKRN3
MOB1A
MOB3C
MORN3
MSS51
MTUS2
MYOZ3
NCOA1
NCOA5
NECAB2
NOS3
NRIP1
NUTM1
OIP5
PAX6
PCBD1
PDE9A
PDLIM7
PFDN6
PIBF1
PLAGL2
PLEKHA2
PNKP
PPP1CB
PRDM14
PRDM6
PRKAR1B
PRMT5
PRPF18
PRPF31
PRR5L
PSEN1
PSMB4
PSTPIP1
RAB11FIP2
RALBP1
RBCK1
RHOH
SCARA5
SCNM1
SERTAD3
SNAPIN
SNW1
SORBS3
SRPK2
STAC
SYT6
TAX1BP1
TEX11
TFIP11
TGM5
THAP1
THAP6
TIFA
TLE5
TOP3B
TRAF1
TRAF2
TRAF4
TRIB3
TRIM35
TRIM54
TSGA10
TSGA10IP
TSPYL6
TXLNA
UBAP2
UBC
USHBP1
UTP14C
VMAC
VPS52
VWC2
WASF3
WASHC1
ZBTB42
ZFP57
ZMAT2
ZMYND12
ZNF212
ZNF414
ZNF512
ZNF648
ZNF774
ZNF784
ZNHIT1
ZRANB1
Entrez ID
148932
25959
HPRD ID
17584
12463
Ensembl ID
ENSG00000142961
ENSG00000197256
Uniprot IDs
Q70IA8
X6R3L3
Q63ZY3
PDB IDs
4HBD
5YBV
6TMD
Enriched GO Terms of Interacting Partners
?
Inner Cell Mass Cell Fate Commitment
Inner Cell Mass Cellular Morphogenesis
Negative Regulation Of Protein Localization To Nucleus
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Cyclin-dependent Protein Kinase Activity
Amide Catabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Signaling
Amyloid Fibril Formation
Regulation Of Protein Localization To Nucleus
Cytosol
Positive Regulation Of Receptor Internalization
Negative Regulation Of Cell Communication
Identical Protein Binding
Phosphate-containing Compound Metabolic Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Hippo Signaling
Negative Regulation Of Cell Cycle
Negative Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of NLRP3 Inflammasome Complex Assembly
Positive Regulation Of Hippo Signaling
Amyloid-beta Complex
Protein Homooligomerization
Growth Cone Lamellipodium
Neuron Projection Organization
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Response To Calcium Ion
Amylin Binding
Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Supramolecular Fiber Organization
Positive Regulation Of Toll Signaling Pathway
Protein Modification Process
L-tryptophan Catabolic Process To Acetyl-CoA
Regulation Of Hippo Signaling
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Nucleoside Phosphotransferase Activity
GMP Catabolic Process To Guanine
Glial Cytoplasmic Inclusion
Classical Lewy Body
Lewy Body Corona
Lewy Neurite
Regulation Of NLRP3 Inflammasome Complex Assembly
Protein Metabolic Process
Negative Regulation Of Protein Localization
Positive Regulation Of Receptor-mediated Endocytosis
Acetylcholine Receptor Activator Activity
Positive Regulation Of Apoptotic Process
Lipoprotein Particle
Positive Regulation Of Protein Import
Glial Cell Development
Protein Binding
Identical Protein Binding
Nucleus
Structural Constituent Of Skin Epidermis
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Tagcloud (Intersection)
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