LATS1 and SSX2IP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LATS1	SSX2IP
Gene Name		large tumor suppressor kinase 1	synovial sarcoma, X breakpoint 2 interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Microtubule Organizing Center Cytosol	Nucleus Cell-cell Adherens Junction Cell Leading Edge Centriolar Satellite Ciliary Basal Body Protein Complex
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Sister Chromatid Segregation Protein Phosphorylation Mitotic Nuclear Division Hormone-mediated Signaling Pathway Keratinocyte Differentiation Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Hippo Signaling Regulation Of Protein Complex Assembly Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cytoplasmic Sequestering Of Protein Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway	Cell Adhesion Regulation Of Rac Protein Signal Transduction Intraciliary Transport Involved In Cilium Morphogenesis Cilium Assembly Centrosome Organization Regulation Of Cell Motility
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS
Protein-Protein Interactions		43 interactors: ALPP AMOT APP AURKB CAV1 CDK1 CEP76 EIF4EBP1 FOXL2 FSD2 GOLGA2 ITCH KRT31 LDOC1 LIMK1 MAGI3 MOAP1 MOB3A MOB3B MOB3C MOB4 NEDD4 NUAK1 NUAK2 PABPN1 PPP1R11 PPP6R3 PTEN RAC1 SMURF1 SMURF2 SPERT SSX2IP STK3 STK4 TAZ TFIP11 TRAF1 WWOX WWP1 WWTR1 YAP1 ZYX	89 interactors: ABLIM3 ACTN1 ACTN2 AEN AP1M1 ARNT2 BEX2 BRCA1 BYSL C11orf54 C14orf105 C19orf66 C20orf195 CARD9 CCHCR1 CCNH CDC23 CDC42 CDCA7L CEP55 CHCHD3 DAXX DRG1 EHHADH EIF4A2 FAM124B FAM161A FAM214A FAM64A FANCL FBF1 FRMD6 GEM GOLGA8F IKBKG INO80B KAT5 KDM1A KIF9 KLHL42 KRT15 KRT31 KRT40 KRTAP10-7 LATS1 LMO2 MFAP1 MLLT4 MORN4 MOS MRPL53 NAA10 NDN NOL12 PHC2 PKN1 POLL PRKAA1 PRMT6 PRPF31 PSMA1 SCNM1 SSX2 SSX3 SYT17 TBP TEAD4 TFIP11 TOP3B TP53BP2 TRIM37 TRIM42 TRIM54 TTC23 WDR5 XIAP YWHAQ YWHAZ ZBTB24 ZGPAT ZMAT2 ZNF124 ZNF250 ZNF3 ZNF417 ZNF587 ZNF792 ZRSR2 ZSCAN12
Entrez ID		9113	117178
HPRD ID		09147	10566
Ensembl ID		ENSG00000131023	ENSG00000117155
Uniprot IDs		O95835	B7ZB07 Q9Y2D8
PDB IDs
Enriched GO Terms of Interacting Partners?		Hippo Signaling Regulation Of Signal Transduction Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Signaling Intracellular Signal Transduction Regulation Of Wnt Signaling Pathway Regulation Of Apoptotic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Death Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Metabolic Process Regulation Of Protein Binding Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Signaling Tissue Development Cellular Protein Catabolic Process Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Cellular Response To Growth Factor Stimulus Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Anatomical Structure Morphogenesis Regulation Of Kinase Activity Signal Transduction Response To Growth Factor Cell Communication Positive Regulation Of Signal Transduction Regulation Of Developmental Growth Protein Catabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Protein Metabolic Process Response To Transforming Growth Factor Beta Cellular Macromolecule Catabolic Process Regulation Of Cell Development Negative Regulation Of Wnt Signaling Pathway Regulation Of Organ Growth Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Protein Kinase Activity Negative Regulation Of Cellular Metabolic Process	Gene Expression RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Organelle Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Chromosome Organization Biosynthetic Process Regulation Of Metabolic Process Signal Transduction By P53 Class Mediator Cellular Process Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Intracellular Signal Transduction Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Histone H3-K4 Methylation Regulation Of Apoptotic Process Regulation Of Cellular Process Viral Process Cellular Response To Stress Cell Cycle Regulation Of Cell Death Chromatin Organization Cell Cycle Process Negative Regulation Of Cell Cycle Activation Of MAPK Activity Response To Ionizing Radiation Chromatin Modification Apoptotic Signaling Pathway Regulation Of Organelle Organization DNA Damage Response, Signal Transduction By P53 Class Mediator Establishment Of Golgi Localization Negative Regulation Of Centriole Replication Positive Regulation Of Cellular Protein Metabolic Process Adherens Junction Organization
Tagcloud ?		accompanying carcinogenic cdc2 conservation corpus flies homologue hyperplastic hypogonadism hypogonadotropic infertility insufficiency lethality lh luteum mammalian melanogaster mosaic pituitary ref reminiscent reproductive rescues retardation sarcomas screens tumorigenesis tumours
Tagcloud (Difference) ?		accompanying carcinogenic cdc2 conservation corpus flies homologue hyperplastic hypogonadism hypogonadotropic infertility insufficiency lethality lh luteum mammalian melanogaster mosaic pituitary ref reminiscent reproductive rescues retardation sarcomas screens tumorigenesis tumours
Tagcloud (Intersection) ?