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SSX2IP and PRKAA1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SSX2IP
PRKAA1
Gene Name
synovial sarcoma, X breakpoint 2 interacting protein
protein kinase, AMP-activated, alpha 1 catalytic subunit
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cell-cell Adherens Junction
Cell Leading Edge
Centriolar Satellite
Ciliary Basal Body
Protein Complex
Intracellular
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Apical Plasma Membrane
AMP-activated Protein Kinase Complex
Molecular Function
Protein Binding
Protein Domain Specific Binding
Chromatin Binding
Protein Kinase Activity
AMP-activated Protein Kinase Activity
CAMP-dependent Protein Kinase Activity
Protein Binding
ATP Binding
Protein C-terminus Binding
Kinase Binding
Histone Serine Kinase Activity
Metal Ion Binding
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
Tau-protein Kinase Activity
[acetyl-CoA Carboxylase] Kinase Activity
Biological Process
Cell Adhesion
Regulation Of Rac Protein Signal Transduction
Intraciliary Transport Involved In Cilium Morphogenesis
Cilium Assembly
Centrosome Organization
Regulation Of Cell Motility
Activation Of MAPK Activity
Response To Hypoxia
Glucose Metabolic Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Cholesterol Biosynthetic Process
Autophagy
Cell Cycle Arrest
Signal Transduction
Positive Regulation Of Cell Proliferation
Insulin Receptor Signaling Pathway
Lipid Biosynthetic Process
Response To UV
Cold Acclimation
Response To Gamma Radiation
Positive Regulation Of Autophagy
Positive Regulation Of Gene Expression
Response To Activity
Wnt Signaling Pathway
Fatty Acid Oxidation
Response To Caffeine
Cellular Response To Nutrient Levels
Negative Regulation Of TOR Signaling
Histone-serine Phosphorylation
Cellular Response To Glucose Starvation
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cholesterol Biosynthetic Process
Positive Regulation Of Glycolytic Process
Negative Regulation Of Glucosylceramide Biosynthetic Process
Rhythmic Process
Negative Regulation Of Lipid Catabolic Process
Protein Heterooligomerization
Fatty Acid Homeostasis
Regulation Of Vesicle-mediated Transport
Cellular Response To Hydrogen Peroxide
Cellular Response To Ethanol
Cellular Response To Hypoxia
Response To Camptothecin
Regulation Of Energy Homeostasis
Negative Regulation Of Glucose Import In Response To Insulin Stimulus
Pathways
Insulin receptor signalling cascade
Regulation of AMPK activity via LKB1
IRS-mediated signalling
Regulation of Rheb GTPase activity by AMPK
mTOR signalling
IRS-related events
mTOR signalling
IGF1R signaling cascade
IRS-related events triggered by IGF1R
IRS-mediated signalling
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
Energy dependent regulation of mTOR by LKB1-AMPK
PKB-mediated events
PI3K Cascade
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Drugs
Adenosine monophosphate
Adenosine triphosphate
Phenformin
Diseases
GWAS
Gastric cancer (
22037551
)
Protein-Protein Interactions
89 interactors:
ABLIM3
ACTN1
ACTN2
AEN
AP1M1
ARNT2
BEX2
BRCA1
BYSL
C11orf54
C14orf105
C19orf66
C20orf195
CARD9
CCHCR1
CCNH
CDC23
CDC42
CDCA7L
CEP55
CHCHD3
DAXX
DRG1
EHHADH
EIF4A2
FAM124B
FAM161A
FAM214A
FAM64A
FANCL
FBF1
FRMD6
GEM
GOLGA8F
IKBKG
INO80B
KAT5
KDM1A
KIF9
KLHL42
KRT15
KRT31
KRT40
KRTAP10-7
LATS1
LMO2
MFAP1
MLLT4
MORN4
MOS
MRPL53
NAA10
NDN
NOL12
PHC2
PKN1
POLL
PRKAA1
PRMT6
PRPF31
PSMA1
SCNM1
SSX2
SSX3
SYT17
TBP
TEAD4
TFIP11
TOP3B
TP53BP2
TRIM37
TRIM42
TRIM54
TTC23
WDR5
XIAP
YWHAQ
YWHAZ
ZBTB24
ZGPAT
ZMAT2
ZNF124
ZNF250
ZNF3
ZNF417
ZNF587
ZNF792
ZRSR2
ZSCAN12
58 interactors:
ABI2
ACACA
AES
BHLHE40
CAB39
CDX4
CFTR
CRTC2
CTBP1
EEF2K
EPM2A
FNIP1
GATA1
GOLGA2
GRIK2
HDAC5
HMBOX1
HOMEZ
IKZF3
INO80E
KRT40
L3MBTL3
MAP3K7
MDM4
MORC4
MTOR
MTUS2
PFKFB2
PHC2
PLEKHA4
PNMA5
PPP2CA
PRKAB1
PRKAB2
PRKAG1
PRKAG3
PSMD11
RAD54B
RAF1
RBPMS
RFX6
RIMBP3
ROPN1
RPTOR
SRPK2
SSX2IP
STK11
THAP1
TOMM34
TRIM27
TRIP6
TSC2
TSC22D4
TXNIP
UBXN11
VPS37B
VPS52
ZBED1
Entrez ID
117178
5562
HPRD ID
10566
04115
Ensembl ID
ENSG00000117155
ENSG00000132356
Uniprot IDs
B7ZB07
Q9Y2D8
Q13131
PDB IDs
Enriched GO Terms of Interacting Partners
?
Gene Expression
RNA Metabolic Process
Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Organelle Organization
Regulation Of Transcription, DNA-templated
Regulation Of Gene Expression
Chromosome Organization
Biosynthetic Process
Regulation Of Metabolic Process
Signal Transduction By P53 Class Mediator
Cellular Process
Cellular Metabolic Process
Cellular Response To DNA Damage Stimulus
Intracellular Signal Transduction
Positive Regulation Of Protein Modification Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle
Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Histone H3-K4 Methylation
Regulation Of Apoptotic Process
Regulation Of Cellular Process
Viral Process
Cellular Response To Stress
Cell Cycle
Regulation Of Cell Death
Chromatin Organization
Cell Cycle Process
Negative Regulation Of Cell Cycle
Activation Of MAPK Activity
Response To Ionizing Radiation
Chromatin Modification
Apoptotic Signaling Pathway
Regulation Of Organelle Organization
DNA Damage Response, Signal Transduction By P53 Class Mediator
Establishment Of Golgi Localization
Negative Regulation Of Centriole Replication
Positive Regulation Of Cellular Protein Metabolic Process
Adherens Junction Organization
Insulin Receptor Signaling Pathway
Cellular Response To Insulin Stimulus
Response To Insulin
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Response To Peptide Hormone
Cellular Response To Hormone Stimulus
Cellular Response To Organonitrogen Compound
Response To Peptide
Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Regulation Of Phosphorus Metabolic Process
Response To Hormone
Cell Cycle Arrest
Regulation Of Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Kinase Activity
Gene Expression
Response To Organonitrogen Compound
Transcription, DNA-templated
Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Cell Cycle
Regulation Of Protein Kinase Activity
Positive Regulation Of Protein Modification Process
RNA Biosynthetic Process
Regulation Of Cell Cycle
Regulation Of Protein Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cellular Ketone Metabolic Process
Biosynthetic Process
Cell Cycle
Response To Organic Substance
Regulation Of Cellular Amino Acid Metabolic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Cellular Metabolic Process
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Phosphorylation
Cellular Response To Organic Substance
Protein Oligomerization
RNA Metabolic Process
Positive Regulation Of Protein Phosphorylation
Protein Heterooligomerization
Negative Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Tagcloud
?
abeta
anticipate
atg7
autophagic
autophagy
catabolic
clearance
cultures
degraded
degrades
enhancing
extracellular
fibrils
inflammasome
ingests
interacts
knockout
lysosomal
map1lc3b
microglia
microglial
native
nlr
nlrp3
optineurin
optn
promising
pyrin
resultant
Tagcloud (Difference)
?
abeta
anticipate
atg7
autophagic
autophagy
catabolic
clearance
cultures
degraded
degrades
enhancing
extracellular
fibrils
inflammasome
ingests
interacts
knockout
lysosomal
map1lc3b
microglia
microglial
native
nlr
nlrp3
optineurin
optn
promising
pyrin
resultant
Tagcloud (Intersection)
?