SSX2IP and MLLT4

Number of citations of the paper that reports this interaction (PMID 12446711)
14

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SSX2IP	MLLT4
Gene Name		synovial sarcoma, X breakpoint 2 interacting protein	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cell-cell Adherens Junction Cell Leading Edge Centriolar Satellite Ciliary Basal Body Protein Complex	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Cell-cell Adherens Junction Cell Junction Apical Part Of Cell
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding Protein C-terminus Binding Ras GTPase Binding Cell Adhesion Molecule Binding
	Biological Process	Cell Adhesion Regulation Of Rac Protein Signal Transduction Intraciliary Transport Involved In Cilium Morphogenesis Cilium Assembly Centrosome Organization Regulation Of Cell Motility	Cell Adhesion Signal Transduction Cell-cell Signaling Positive Regulation Of Rap GTPase Activity Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization Establishment Of Endothelial Intestinal Barrier
Pathways
Drugs
Diseases
GWAS			Metabolite levels (5-HIAA) ( 23319000)
Protein-Protein Interactions		89 interactors: ABLIM3 ACTN1 ACTN2 AEN AP1M1 ARNT2 BEX2 BRCA1 BYSL C11orf54 C14orf105 C19orf66 C20orf195 CARD9 CCHCR1 CCNH CDC23 CDC42 CDCA7L CEP55 CHCHD3 DAXX DRG1 EHHADH EIF4A2 FAM124B FAM161A FAM214A FAM64A FANCL FBF1 FRMD6 GEM GOLGA8F IKBKG INO80B KAT5 KDM1A KIF9 KLHL42 KRT15 KRT31 KRT40 KRTAP10-7 LATS1 LMO2 MFAP1 MLLT4 MORN4 MOS MRPL53 NAA10 NDN NOL12 PHC2 PKN1 POLL PRKAA1 PRMT6 PRPF31 PSMA1 SCNM1 SSX2 SSX3 SYT17 TBP TEAD4 TFIP11 TOP3B TP53BP2 TRIM37 TRIM42 TRIM54 TTC23 WDR5 XIAP YWHAQ YWHAZ ZBTB24 ZGPAT ZMAT2 ZNF124 ZNF250 ZNF3 ZNF417 ZNF587 ZNF792 ZRSR2 ZSCAN12	37 interactors: BCR CTNNA1 EPHA7 EPHB2 EPHB3 EPHB6 F11R HRAS JAG1 LMO2 MRAS NRXN1 NRXN2 NRXN3 PFN1 PICK1 PVRL1 PVRL2 PVRL3 PVRL4 RALGDS RAP1A RAP1GAP RAP2A RIN1 RIT1 RIT2 RRAS RRAS2 SMAD2 SORBS1 SORBS2 SSX2IP TJP1 USP9X YWHAB YWHAG
Entrez ID		117178	4301
HPRD ID		10566	01164
Ensembl ID		ENSG00000117155	ENSG00000130396
Uniprot IDs		B7ZB07 Q9Y2D8	P55196
PDB IDs			1T2M 1XZ9 2AIN 2EXG
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Organelle Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Chromosome Organization Biosynthetic Process Regulation Of Metabolic Process Signal Transduction By P53 Class Mediator Cellular Process Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Intracellular Signal Transduction Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Histone H3-K4 Methylation Regulation Of Apoptotic Process Regulation Of Cellular Process Viral Process Cellular Response To Stress Cell Cycle Regulation Of Cell Death Chromatin Organization Cell Cycle Process Negative Regulation Of Cell Cycle Activation Of MAPK Activity Response To Ionizing Radiation Chromatin Modification Apoptotic Signaling Pathway Regulation Of Organelle Organization DNA Damage Response, Signal Transduction By P53 Class Mediator Establishment Of Golgi Localization Negative Regulation Of Centriole Replication Positive Regulation Of Cellular Protein Metabolic Process Adherens Junction Organization	Signaling Cell Communication Enzyme Linked Receptor Protein Signaling Pathway Anatomical Structure Development Developmental Process Cell Development Cell Projection Organization Signal Transduction Nervous System Development Axon Development Cellular Response To Stimulus Generation Of Neurons Anatomical Structure Morphogenesis Neurogenesis Response To Stimulus Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Axonogenesis Cell Part Morphogenesis System Development Cell Differentiation Neuron Differentiation Ras Protein Signal Transduction Multicellular Organismal Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Development Neuron Projection Development Neuron Projection Morphogenesis Locomotion Cell Projection Morphogenesis Regulation Of Signaling Cell Junction Assembly Cell Morphogenesis Involved In Differentiation Cell-cell Junction Organization Regulation Of Cellular Component Organization Cell Adhesion Chemotaxis Small GTPase Mediated Signal Transduction Movement Of Cell Or Subcellular Component Cell Morphogenesis Response To External Stimulus Adherens Junction Organization Cellular Component Assembly Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Signal Transduction Regulation Of Synapse Assembly Cellular Response To Organic Substance Response To Organic Substance Learning
Tagcloud ?			abl1 aff1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mllt1 mllt10 mllt3 mllt6 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16
Tagcloud (Difference) ?			abl1 aff1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mllt1 mllt10 mllt3 mllt6 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16
Tagcloud (Intersection) ?