SSX2IP and TEAD4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SSX2IP	TEAD4
Description		SSX family member 2 interacting protein	TEA domain transcription factor 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytoskeleton Adherens Junction Cell Leading Edge Protein-containing Complex Centriolar Satellite Ciliary Basal Body Cell Projection Anchoring Junction	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Protein-DNA Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Centrosome Cycle Cell Adhesion Cell Projection Organization Regulation Of Rac Protein Signal Transduction Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Regulation Of Cell Motility	Skeletal System Development In Utero Embryonic Development Cell Fate Specification Blastocyst Formation Trophectodermal Cell Fate Commitment DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Embryo Implantation Hippo Signaling Cell Fate Commitment Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Positive Regulation Of Stem Cell Population Maintenance
Pathways			YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription Formation of axial mesoderm Zygotic genome activation (ZGA) Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS		Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737) Waist-to-hip ratio adjusted for body mass index ( 28430825)	Narcolepsy with cataplexy ( 23496005)
Interacting Genes		114 interacting genes: ABLIM3 ACTN1 ACTN2 AEN AFDN AP1M1 ARNT2 ATOSA BCL6 BEX2 BKGD BRCA1 BYSL CARD9 CCDC187 CCDC198 CCHCR1 CCNH CDC23 CDC42 CDCA7L CHCHD3 DAXX DRG1 DVL2 EAF2 EHHADH EIF4A2 ERAL1 FAM124B FAM161A FANCG FANCL FBF1 FNDC11 FRMD6 GEM GOLGA2 GOLGA8F GRAP2 HDAC4 HNRNPLL IKBKG INO80B KAT5 KDM1A KIF9 KIFC3 KLHL42 KRT15 KRT31 KRT40 KRTAP10-7 LATS1 LMO2 MCM7 MFAP1 MORN4 MOS MRPL53 NAA10 NDN NIF3L1 NOL12 NTAQ1 PHC2 PIMREG PKN1 PNMA1 POLL PRKAA1 PRKAB2 PRMT6 PRPF3 PRPF31 PSMA1 RAB1A RNF6 SCNM1 SHFL SSX2 SSX3 SYT17 TBP TEAD4 TFIP11 TOP3B TRIM42 TRIM54 TSGA10IP TSTD2 TTC23 WDR5 XIAP YWHAQ YWHAZ ZBTB24 ZFYVE26 ZGPAT ZMAT2 ZNF124 ZNF202 ZNF250 ZNF3 ZNF408 ZNF417 ZNF438 ZNF587 ZNF648 ZNF688 ZNF71 ZNF792 ZRSR2 ZSCAN12	50 interacting genes: CCDC125 CCDC172 CCDC85B CCNDBP1 CDR2 CEP55 CEP70 CRYAA CTBP1 DYDC1 EXOC3-AS1 FBXO7 GOLGA2 GOLGA6L9 HAUS1 HOMEZ INCA1 KIAA0753 KRT27 KRT31 KRT40 KRTAP10-3 LDOC1 LZTS2 MDFI MTUS2 MYH7 NUTM1 PDE4DIP PFKM PNMA1 PRDM14 PRKAR1B RABGEF1 RASSF10 RUNDC3A RUNX1 SAT1 SESTD1 SORBS3 SSX2IP TLE5 TRAF1 TRIM54 VGLL1 VGLL3 VPS52 VTA1 WWTR1 YAP1
Entrez ID		117178	7004
HPRD ID		10566	03421
Ensembl ID		ENSG00000117155	ENSG00000197905
Uniprot IDs		B7ZB07 Q9Y2D8	Q15561
PDB IDs			5GZB 5NO6 5OAQ 6GE3 6GE4 6GE5 6GE6 6GEC 6GEE 6GEG 6GEI 6GEK 6HIK 6Q2X 6Q36 6SEN 6SEO 8A8R 8C17 8CAA
Enriched GO Terms of Interacting Partners?		Nucleus Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Zinc Ion Binding Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Nuclear Androgen Receptor Binding Metal Ion Binding Regulation Of Metabolic Process DNA Damage Response DNA Recombination DNA-binding Transcription Factor Binding Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Spliceosomal Complex Mitotic Spindle U2-type Precatalytic Spliceosome Keratin Filament MRNA Splicing, Via Spliceosome DNA Binding RNA Splicing, Via Transesterification Reactions Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleic Acid Metabolic Process AMP-activated Protein Kinase Activity Transcription Coactivator Activity Protein K6-linked Ubiquitination	Cytoskeleton Microtubule Organizing Center Organization Centrosome Cycle Centrosome Cytoplasm Cardiac Muscle Tissue Regeneration Protein Binding Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Keratin Filament
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