RGL2 and KAT7

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RGL2	KAT7
Gene Name		ral guanine nucleotide dissociation stimulator-like 2	K(lysine) acetyltransferase 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Intracellular	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Ras Guanyl-nucleotide Exchange Factor Activity	Sequence-specific DNA Binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding
	Biological Process	Ras Protein Signal Transduction Positive Regulation Of Ras GTPase Activity	DNA Replication Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CCDC90B CRMP1 EEF1G HRAS KAT5 KAT7 KPNA2 KRAS NOTCH2NL NRAS RAC1 RALA RAP1B UNC119	43 interactors: APP AR ATN1 BARD1 CAAP1 CALCOCO2 CBX8 CDC6 CDK11B CEP70 CSNK1E DDX11 DVL3 DYNC1I1 GMNN HAP1 HIST1H3A HIST1H4A HIST2H2AC HOOK2 ING4 JADE1 KATNBL1 KCTD13 KIAA1377 LRIF1 MCM2 NINL ORC1 ORC2 PACSIN1 POLB PPID RGL2 RPS10 SAT1 SEPT5 SNAPIN TP53 VIM WDR33 ZBTB8A ZNF165
Entrez ID		5863	11143
HPRD ID		03810	07135
Ensembl ID		ENSG00000237441	ENSG00000136504
Uniprot IDs		O15211	O95251
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rac Protein Signal Transduction Neurotrophin Signaling Pathway Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Small GTPase Mediated Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Positive Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Transferase Activity Cellular Response To Growth Factor Stimulus Chemotaxis Response To Growth Factor Small GTPase Mediated Signal Transduction Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Synaptic Transmission, GABAergic Regulation Of Rac Protein Signal Transduction Response To External Stimulus Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Axon Guidance Cellular Response To Organic Substance Regulation Of Kinase Activity Blood Coagulation Hemostasis Epithelial Tube Branching Involved In Lung Morphogenesis Response To Radiation Positive Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Neuronal Synaptic Plasticity Visual Learning Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Activation Of MAPKK Activity Lung Morphogenesis Visual Behavior Axonogenesis Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Protein Phosphorylation Fc Receptor Signaling Pathway Wound Healing Actin Cytoskeleton Organization Response To Abiotic Stimulus Associative Learning Positive Regulation Of Cell Projection Organization Response To Organic Substance Neuron Projection Morphogenesis	Cell Cycle Cell Cycle Process Mitotic Cell Cycle DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Organelle Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Replication Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA-dependent DNA Replication Negative Regulation Of Biosynthetic Process Neuron Apoptotic Process Regulation Of RNA Metabolic Process Apoptotic Process Neuron Death Programmed Cell Death Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Replication Initiation Regulation Of Cell Cycle Establishment Of Vesicle Localization Vesicle Localization Negative Regulation Of Cellular Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Viral Process Chromosome Organization Regulation Of Cell Cycle Phase Transition Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of DNA Replication Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Microtubule-based Transport
Tagcloud ?		21d abi3 abscisic aco4 albeit alternating biosynthetic della disparate domesticated dormancy dormant ethylene germinate germinating germination gibberellin hub hy5 imbibed imbibition leafy phenylpropanoid seeds spurge surge temperate temporary transcriptome	acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts
Tagcloud (Difference) ?		21d abi3 abscisic aco4 albeit alternating biosynthetic della disparate domesticated dormancy dormant ethylene germinate germinating germination gibberellin hub hy5 imbibed imbibition leafy phenylpropanoid seeds spurge surge temperate temporary transcriptome	acetyltransferase acetyltransferases analogs anticancer assayed campaign cascades deacetylases discover docked extremely gcn5 ic50 kat3b kat5 kat6b l002 mb mda methyltransferases mumol nci nsc764414 paralog potently therapeutics throughput tnbc xenografts
Tagcloud (Intersection) ?