| Description | tankyrase | axin 1 | 
    
      | Image |  |  | 
    
 
     | Cellular Component |  |  | 
    
      | Molecular Function |  |  | 
    
      | Biological Process |  |  | 
    
      | Pathways |  |  | 
    
      | Drugs |  |  | 
    
      | Diseases |  |  | 
    
      | GWAS | 
                          A body shape index ( 34021172)Acne (severe) ( 24927181)Age at first birth ( 34211149)Alanine aminotransferase levels ( 34315874 33547301)Aspartate aminotransferase levels ( 34315874)Bipolar disorder ( 31043756)Bone mineral density (Ward's triangle area) ( 27397699)Brain morphology (MOSTest) ( 32665545)Cataracts (operation) ( 31816047)Deep white matter hyperintensities ( 32517579)Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)Fish- and plant-related diet ( 32066663)General risk tolerance (MTAG) ( 30643258)Joint mobility (Beighton score) ( 27182965)LDL cholesterol levels ( 32203549)Metabolite levels ( 22916037)Mosquito bite size ( 28199695)Nose size ( 27182965)Obesity (early onset extreme) ( 20421936)Oily fish consumption ( 32066663)Pork consumption ( 32066663)Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)Refractive error ( 32231278)Regular attendance at a religious group ( 29970889)Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382)Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578)Schizophrenia ( 26198764)Serum alkaline phosphatase levels ( 33547301)Systemic lupus erythematosus ( 28714469)Systolic blood pressure ( 30224653)Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)Triglyceride levels ( 32154731)Type 2 diabetes ( 30054458)Waist circumference adjusted for body mass index ( 34021172)Waist-hip index ( 34021172)Waist-to-hip ratio adjusted for BMI ( 34021172)White matter hyperintensity volume ( 33293549)White matter hyperintensity volume (adjusted for hypertension) ( 33293549)White matter hyperintensity volume x hypertension interaction (2df) ( 33293549) |  | 
    
	
    
				
    
      | Interacting Genes | 34 interacting genes:
                  ADPRS
                  ANKRD28
                  AXIN1
                  CACNA1S
                  CDKN1A
                  DTNBP1
                  EIF4A1
                  ENDOG
                  EPM2AIP1
                  FANCD2
                  FNBP1
                  GMDS
                  HNRNPM
                  INPP5K
                  LNPEP
                  MAVS
                  MCL1
                  NELFE
                  NUMA1
                  OARD1
                  PLCH2
                  POT1
                  PTEN
                  RNF146
                  RUNDC1
                  SDCBP
                  TCL1A
                  TERF1
                  TNIK
                  TNKS1BP1
                  TNKS2
                  UBASH3B
                  USP25
                  VPS33A | 91 interacting genes:
                  AMER1
                  ANP32A
                  APC
                  BTRC
                  CALCOCO2
                  CARD9
                  CARM1
                  CCDC57
                  CDCA7L
                  CRMP1
                  CSNK1A1
                  CSNK1E
                  CTNNB1
                  DAB2
                  DIXDC1
                  DVL1
                  DVL2
                  DVL3
                  EEF1A1
                  ENTR1
                  ETV6
                  FXR1
                  FXR2
                  GAK
                  GMCL1
                  GNAS
                  GOLGA2
                  GSK3B
                  HOMEZ
                  JUP
                  KAT5
                  KRT40
                  KRTAP10-3
                  KRTAP4-12
                  KRTAP4-2
                  LHX4
                  LHX8
                  LMO2
                  LRP5
                  LRP6
                  MAP3K4
                  MDFI
                  MEOX2
                  MID2
                  MTUS2
                  MYC
                  MYOT
                  NBR1
                  NCK2
                  NUTM1
                  PIAS1
                  PML
                  PPP2CA
                  PPP2CB
                  PPP2R5B
                  PPP2R5C
                  PRMT1
                  PSTPIP1
                  RCHY1
                  RNF111
                  RUNX2
                  SCYL1
                  SENP2
                  SH3GL1
                  SIAH1
                  SMAD2
                  SMAD3
                  SMAD7
                  SMURF1
                  SMURF2
                  STX11
                  SUMO1
                  SUMO1P1
                  TFIP11
                  TNKS
                  TP53BP2
                  TRAF2
                  TRIM15
                  TRIM27
                  TRIM37
                  TRIM42
                  TRIP6
                  TSC1
                  TSGA10
                  UCHL5
                  USP10
                  USP7
                  UTP14A
                  WSB1
                  ZBTB26
                  ZFYVE19 | 
				
    
      | Entrez ID | 8658 | 8312 | 
    
      | HPRD ID | 04490 | 04819 | 
    
      | Ensembl ID | ENSG00000173273 | ENSG00000103126 | 
    
      | Uniprot IDs | H0YAW5 
                O95271 | A0A0S2Z4R0 
                A0A0S2Z4S3 
                O15169 | 
    
      | PDB IDs | 2RF5 
                    3UDD 
                    3UH2 
                    3UH4 
                    4DVI 
                    4I9I 
                    4K4E 
                    4K4F 
                    4KRS 
                    4LI6 
                    4LI7 
                    4LI8 
                    4MSG 
                    4MSK 
                    4MT9 
                    4N3R 
                    4N4V 
                    4OA7 
                    4TOR 
                    4TOS 
                    4U6A 
                    4UUH 
                    4UW1 
                    4W5S 
                    4W6E 
                    5EBT 
                    5ECE 
                    5ETY 
                    5GP7 
                    5JHQ 
                    5JTI 
                    5JU5 
                    5KNI 
                    6QXU 
                    6URQ 
                    7KKM 
                    7KKN 
                    7KKO 
                    7KKP 
                    7KKQ 
                    7OCV 
                    8X5J | 1DK8 
                    1EMU 
                    1O9U 
                    3ZDI 
                    4B7T 
                    4NM0 
                    4NM3 
                    4NM5 
                    4NM7 
                    4NU1 
                    5WZZ 
                    6JCK 
                    7SXF 
                    7SXG 
                    7SXH 
                    7SXJ 
                    7Y1P 
                    8RU3 
                    8RU4 
                    8VMG | 
    
      | Enriched GO Terms of Interacting Partners? |  |  | 
    
      | Tagcloud ? |  |  | 
    
      | Tagcloud (Difference) ? |  |  | 
    
      | Tagcloud (Intersection) ? |  |