AXIN1 and SMURF2

  • Number of citations of the paper that reports this interaction (PMID 20858899)
  • 10
  • Data Source:
  • BioGRID (enzymatic study, affinity chromatography technology)

AXIN1

SMURF2

Gene Name axin 1 SMAD specific E3 ubiquitin protein ligase 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 43 interactors: AMER1 ANP32A APC BTRC CARM1 CRMP1 CSNK1A1 CSNK1E CTNNB1 DAB2 DIXDC1 DVL1 DVL2 DVL3 EEF1A1 GAK GNAS GSK3B JUP LMO2 LRP5 LRP6 MAP3K4 MYC MYOT NCK2 PIAS1 PML PPP2CA PPP2CB PPP2R5B PPP2R5C PRMT1 RNF111 RUNX2 SENP2 SH3GL1 SMAD2 SMAD3 SMAD7 SMURF1 SMURF2 UTP14A 79 interactors: ACBD3 ACOX3 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FAM175B FKBP4 FLNB GNG2 HDGFRP3 ING2 IRF3 IRF8 KLF5 LAPTM5 LATS1 MAVS NEK6 NKIRAS1 NRAS PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNRNP70 SOCS6 SPG20 SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D3 UBE2L3 YY1 ZBTB44
Entrez ID 8312 64750
HPRD ID 04819 06901
Ensembl ID ENSG00000103126
Uniprot IDs O15169 Q96DE7 Q9HAU4
PDB IDs 1DK8 1EMU 1O9U 3ZDI 4B7T 1ZVD 2DJY 2JQZ 2KXQ 2LTZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aberrations  applying  arid2  cdk15  cps1  creating  deleterious  disruptions  drive  driver  fn1  fusions  genomes  hccs  hnf4a  integrations  intronic  mll4  recurrently  rps6ka3  seq  silent  splice  tert  thrap3  transcriptomes  transcriptomic  tsc1  wgs 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Difference) ?
aberrations  applying  arid2  cdk15  cps1  creating  deleterious  disruptions  drive  driver  fn1  fusions  genomes  hccs  hnf4a  integrations  intronic  mll4  recurrently  rps6ka3  seq  silent  splice  tert  thrap3  transcriptomes  transcriptomic  tsc1  wgs 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Intersection) ?